(4 nodes) (2023) Aging affects the number and morphological heterogeneity of rat phrenic motor neurons and phrenic motor axons. network (Canis lupus familiaris)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	MYH1	Myosin-1; Muscle contraction. (1953 aa)
	MYH2	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1940 aa)
	MYH6	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
	MYH4	Myosin-4; Muscle contraction. (1939 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYH1	MYH2	ENSCAFP00000025847	ENSCAFP00000025869	Myosin-1; Muscle contraction.	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	0.644
MYH1	MYH4	ENSCAFP00000025847	ENSCAFP00000025934	Myosin-1; Muscle contraction.	Myosin-4; Muscle contraction.	0.573
MYH1	MYH6	ENSCAFP00000025847	ENSCAFP00000053932	Myosin-1; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.654
MYH2	MYH1	ENSCAFP00000025869	ENSCAFP00000025847	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	Myosin-1; Muscle contraction.	0.644
MYH2	MYH4	ENSCAFP00000025869	ENSCAFP00000025934	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	Myosin-4; Muscle contraction.	0.556
MYH2	MYH6	ENSCAFP00000025869	ENSCAFP00000053932	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.655
MYH4	MYH1	ENSCAFP00000025934	ENSCAFP00000025847	Myosin-4; Muscle contraction.	Myosin-1; Muscle contraction.	0.573
MYH4	MYH2	ENSCAFP00000025934	ENSCAFP00000025869	Myosin-4; Muscle contraction.	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	0.556
MYH4	MYH6	ENSCAFP00000025934	ENSCAFP00000053932	Myosin-4; Muscle contraction.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.637
MYH6	MYH1	ENSCAFP00000053932	ENSCAFP00000025847	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-1; Muscle contraction.	0.654
MYH6	MYH2	ENSCAFP00000053932	ENSCAFP00000025869	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity).	0.655
MYH6	MYH4	ENSCAFP00000053932	ENSCAFP00000025934	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin-4; Muscle contraction.	0.637