STRINGSTRING
MYO1H MYO1H ADGB ADGB MYO3A MYO3A IQCA1L IQCA1L SCN5A SCN5A RNF32 RNF32 MYO7A MYO7A CEP131 CEP131 XKR7 XKR7 SCN8A SCN8A IQCM IQCM MYH7B MYH7B IQCD IQCD CEP97 CEP97 IQCF1 IQCF1 IQCF2 IQCF2 IQCF5 IQCF5 MYO1B MYO1B GAP43 GAP43 SCN3A SCN3A NRGN NRGN ASPM ASPM SCN1A SCN1A SCN9A SCN9A IQCB1 IQCB1 SCN7A SCN7A MYO18B MYO18B IQCA1 IQCA1 SCN4A SCN4A MYO3B MYO3B IQCG IQCG IQGAP1 IQGAP1 PPEF1 PPEF1 LRRIQ4 LRRIQ4 IQCN IQCN MYH16 MYH16 CAMTA2 CAMTA2 IQCH IQCH MYH13 MYH13 MYH8 MYH8 MYH1 MYH1 MYH2 MYH2 MYH3 MYH3 MYH4 MYH4 MYO9A MYO9A MYO19 MYO19 IQCK IQCK MYO1F MYO1F MYO1C MYO1C LRRIQ3 LRRIQ3 MYO7B MYO7B SPA17 SPA17 RASGRF2 RASGRF2 IQCF6 IQCF6 SPEGNB SPEGNB MARF1 MARF1 MYO5B MYO5B SPATA17 SPATA17 INVS INVS MYO5A MYO5A MYH15 MYH15 IQCE IQCE MYH6 MYH6 RASGRF1 RASGRF1 MYO1A MYO1A MYO18A MYO18A MYH9 MYH9 MYO6 MYO6 LRRIQ1 LRRIQ1 SCN2A SCN2A PPEF2 PPEF2 MYO9B MYO9B IQCF3 IQCF3 UBE3B UBE3B CAMTA1 CAMTA1 IQGAP2 IQGAP2 MYH10 MYH10 DCAF6 DCAF6 MYH14 MYH14 MYO10 MYO10 UBE3C UBE3C MYO1D MYO1D IQGAP3 IQGAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1164 aa)
ADGBAndroglobin; Belongs to the peptidase C2 family. (1653 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1614 aa)
IQCA1LIQ motif containing with AAA domain 1 like. (815 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2013 aa)
RNF32Ring finger protein 32. (369 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2215 aa)
CEP131Centrosomal protein 131. (1000 aa)
XKR7XK-related protein. (581 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1991 aa)
IQCMIQ motif containing M. (462 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1844 aa)
IQCDIQ motif containing D. (451 aa)
CEP97Centrosomal protein 97. (852 aa)
IQCF1IQ motif containing F1. (207 aa)
IQCF2IQ motif containing F2. (162 aa)
IQCF5IQ motif containing F5. (147 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
GAP43Growth associated protein 43. (291 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1998 aa)
NRGNNeurogranin. (78 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3469 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1938 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1986 aa)
IQCB1IQ motif containing B1. (598 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1677 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2557 aa)
IQCA1IQ motif containing with AAA domain 1. (792 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1837 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1342 aa)
IQCGIQ motif containing G. (438 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (661 aa)
LRRIQ4Leucine rich repeats and IQ motif containing 4. (559 aa)
IQCNUncharacterized protein. (1575 aa)
MYH16Myosin-16; May play a role in masticatory muscles contraction. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1945 aa)
CAMTA2Calmodulin binding transcription activator 2. (1298 aa)
IQCHIQ motif containing H. (1029 aa)
MYH13Myosin-13; Fast twitching myosin mediating the high-velocity and low- tension contractions of specific striated muscles; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
MYH8Myosin-8; Muscle contraction. (1940 aa)
MYH1Myosin-1; Muscle contraction. (1953 aa)
MYH2Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1940 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
MYH4Myosin-4; Muscle contraction. (1939 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2628 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (984 aa)
IQCKIQ motif containing K. (287 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1069 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
LRRIQ3Leucine rich repeats and IQ motif containing 3. (621 aa)
MYO7BMyosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2143 aa)
SPA17Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates. (151 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1215 aa)
IQCF6IQ motif containing F6. (127 aa)
SPEGNBSPEG neighbor. (238 aa)
MARF1Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
MYO5BMyosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1873 aa)
SPATA17Spermatogenesis associated 17. (392 aa)
INVSInversin; Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin- proteasome. This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity). Does n [...] (1083 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1908 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1807 aa)
IQCEIQ motif containing E. (886 aa)
MYH6Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1306 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1103 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2704 aa)
MYH9Myosin-9; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa)
LRRIQ1Leucine rich repeats and IQ motif containing 1. (1697 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
PPEF2Uncharacterized protein. (153 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2271 aa)
IQCF3Uncharacterized protein. (233 aa)
UBE3BUbiquitin protein ligase E3B. (1132 aa)
CAMTA1Calmodulin binding transcription activator 1. (1673 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1621 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2077 aa)
DCAF6DDB1 and CUL4 associated factor 6. (977 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2072 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2035 aa)
UBE3CUbiquitin protein ligase E3C. (1273 aa)
MYO1DUnconventional myosin-Id; Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity). (958 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1733 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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