(46 nodes) Ubiquitin homologues network (Canis lupus familiaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCAFP00000050780	Ubiquitin-like domain-containing protein. (151 aa)
	ENSCAFP00000054759	Ubiquitin-like domain-containing protein. (144 aa)
	RAD23A	RAD23 homolog A, nucleotide excision repair protein. (528 aa)
	ENSCAFP00000058401	annotation not available (128 aa)
	ENSCAFP00000059052	Ubiquitin-like domain-containing protein. (241 aa)
	ENSCAFP00000061156	Ubiquitin-like domain-containing protein. (109 aa)
	ENSCAFP00000063070	Ubiquitin-like domain-containing protein. (62 aa)
	UBB	Ubiquitin B. (174 aa)
	UBL7	Ubiquitin like 7. (428 aa)
	UHRF2	Ubiquitin like with PHD and ring finger domains 2. (803 aa)
	LOC100685053	Ubiquitin-like domain-containing protein. (77 aa)
	BAG6	BCL2 associated athanogene 6. (1167 aa)
	UBQLN1	Ubiquilin 1. (637 aa)
	BAG1	BCL2 associated athanogene 1. (458 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (406 aa)
	HERPUD2	HERPUD family member 2. (406 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)
	TMUB1	Transmembrane and ubiquitin like domain containing 1. (294 aa)
	ZFAND4	Uncharacterized protein. (740 aa)
	SACS	Sacsin molecular chaperone. (4561 aa)
	OASL	2'-5' oligoadenylate synthetase-like 1. (515 aa)
	OASL-2	Oligoadenylate synthetase-like 2. (519 aa)
	NEDD8	NEDD8 ubiquitin like modifier. (81 aa)
	SF3A1	Splicing factor 3a subunit 1. (793 aa)
	UBA52	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (128 aa)
	UBTD2	Ubiquitin domain containing 2. (236 aa)
	UBQLN4	Ubiquilin 4. (600 aa)
	UBLCP1	Ubiquitin like domain containing CTD phosphatase 1. (318 aa)
	NFATC2IP	Nuclear factor of activated T cells 2 interacting protein. (410 aa)
	UBFD1	Ubiquitin family domain containing 1. (310 aa)
	USP14	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (545 aa)
	UHRF1	Ubiquitin like with PHD and ring finger domains 1. (792 aa)
	ISG15	ISG15 ubiquitin like modifier. (168 aa)
	ELOB	Elongin B. (115 aa)
	UBL4A	Ubiquitin like 4A. (159 aa)
	DDI1	DNA damage inducible 1 homolog 1. (395 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	LOC102152113	Uncharacterized protein. (547 aa)
	FAU	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa)
	UBQLN3	Ubiquilin 3. (705 aa)
	HERPUD1	Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)
	TMUB2	Transmembrane and ubiquitin like domain containing 2. (286 aa)
	UBQLNL	Ubiquilin like. (583 aa)
	TINCR	TINCR ubiquitin domain containing. (87 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (464 aa)
	UBL4B	Ubiquitin like 4B. (202 aa)

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG6	ENSCAFP00000054759	ENSCAFP00000000828	ENSCAFP00000054759	BCL2 associated athanogene 6.	Ubiquitin-like domain-containing protein.	0.443
BAG6	ENSCAFP00000061156	ENSCAFP00000000828	ENSCAFP00000061156	BCL2 associated athanogene 6.	Ubiquitin-like domain-containing protein.	0.443
BAG6	FAU	ENSCAFP00000000828	ENSCAFP00000033982	BCL2 associated athanogene 6.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.443
BAG6	UBL4A	ENSCAFP00000000828	ENSCAFP00000028970	BCL2 associated athanogene 6.	Ubiquitin like 4A.	0.767
BAG6	UBL4B	ENSCAFP00000000828	ENSCAFP00000053162	BCL2 associated athanogene 6.	Ubiquitin like 4B.	0.767
BAG6	UBL7	ENSCAFP00000000828	ENSCAFP00000063414	BCL2 associated athanogene 6.	Ubiquitin like 7.	0.503
BAG6	UBQLN4	ENSCAFP00000000828	ENSCAFP00000024831	BCL2 associated athanogene 6.	Ubiquilin 4.	0.633
DDI1	RAD23A	ENSCAFP00000031155	ENSCAFP00000055222	DNA damage inducible 1 homolog 1.	RAD23 homolog A, nucleotide excision repair protein.	0.689
DDI1	RAD23B	ENSCAFP00000031155	ENSCAFP00000004125	DNA damage inducible 1 homolog 1.	RAD23 homolog B, nucleotide excision repair protein.	0.620
DDI1	UBLCP1	ENSCAFP00000031155	ENSCAFP00000025471	DNA damage inducible 1 homolog 1.	Ubiquitin like domain containing CTD phosphatase 1.	0.495
DDI1	UBQLN1	ENSCAFP00000031155	ENSCAFP00000002072	DNA damage inducible 1 homolog 1.	Ubiquilin 1.	0.415
DDI1	UBQLNL	ENSCAFP00000031155	ENSCAFP00000040806	DNA damage inducible 1 homolog 1.	Ubiquilin like.	0.415
ELOB	ENSCAFP00000050780	ENSCAFP00000028588	ENSCAFP00000050780	Elongin B.	Ubiquitin-like domain-containing protein.	0.629
ELOB	NEDD8	ENSCAFP00000028588	ENSCAFP00000017809	Elongin B.	NEDD8 ubiquitin like modifier.	0.926
ELOB	RPS27A	ENSCAFP00000028588	ENSCAFP00000031429	Elongin B.	Ubiquitin-like domain-containing protein.	0.629
ELOB	UBA52	ENSCAFP00000028588	ENSCAFP00000021714	Elongin B.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.559
ELOB	UBB	ENSCAFP00000028588	ENSCAFP00000063279	Elongin B.	Ubiquitin B.	0.624
ENSCAFP00000050780	ELOB	ENSCAFP00000050780	ENSCAFP00000028588	Ubiquitin-like domain-containing protein.	Elongin B.	0.629
ENSCAFP00000050780	ENSCAFP00000054759	ENSCAFP00000050780	ENSCAFP00000054759	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.995
ENSCAFP00000050780	ENSCAFP00000058401	ENSCAFP00000050780	ENSCAFP00000058401	Ubiquitin-like domain-containing protein.	annotation not available	0.956