STRINGSTRING
IL1RL1 IL1RL1 IL18RAP IL18RAP IL1RL2 IL1RL2 MYD88 MYD88 TLR2 TLR2 TLR5 TLR5 IL1RAPL1 IL1RAPL1 IL1RAP IL1RAP TLR6 TLR6 TLR10 TLR10 IL1RAPL2 IL1RAPL2 SARM1 SARM1 TLR4 TLR4 TLR1 TLR1 TLR3 TLR3 IL1R1 IL1R1 IL18R1 IL18R1 LOC491698 LOC491698
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL1RL1Interleukin 1 receptor like 1. (557 aa)
IL18RAPInterleukin 18 receptor accessory protein. (582 aa)
IL1RL2Interleukin 1 receptor like 2. (578 aa)
MYD88MYD88 innate immune signal transduction adaptor. (398 aa)
TLR2Toll-like receptor 2; Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequentl [...] (802 aa)
TLR5TIR domain-containing protein; Belongs to the Toll-like receptor family. (1093 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (696 aa)
IL1RAPInterleukin 1 receptor accessory protein. (685 aa)
TLR6Toll like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
TLR10Toll like receptor 10; Belongs to the Toll-like receptor family. (807 aa)
IL1RAPL2Interleukin 1 receptor accessory protein like 2. (686 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (833 aa)
TLR1Toll like receptor 1; Belongs to the Toll-like receptor family. (760 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (967 aa)
IL1R1Interleukin 1 receptor type 1. (629 aa)
IL18R1Interleukin 18 receptor 1. (718 aa)
LOC491698TIR domain-containing protein. (409 aa)
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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