Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAM17 | APP | ENSCAFP00000051611 | ENSCAFP00000012583 | Uncharacterized protein. | Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...] | 0.615 |
| ADAM17 | EGF | ENSCAFP00000051611 | ENSCAFP00000016954 | Uncharacterized protein. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). | 0.435 |
| ADAM17 | EGFR | ENSCAFP00000051611 | ENSCAFP00000005164 | Uncharacterized protein. | Receptor protein-tyrosine kinase. | 0.620 |
| ADAM17 | GSK3B | ENSCAFP00000051611 | ENSCAFP00000034412 | Uncharacterized protein. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.401 |
| ADAM17 | JAG1 | ENSCAFP00000051611 | ENSCAFP00000008417 | Uncharacterized protein. | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.466 |
| ADAM17 | NOTCH1 | ENSCAFP00000051611 | ENSCAFP00000029073 | Uncharacterized protein. | Notch receptor 1. | 0.937 |
| ADAM17 | NOTCH2 | ENSCAFP00000051611 | ENSCAFP00000015629 | Uncharacterized protein. | Notch receptor 2. | 0.921 |
| ADAM17 | NOTCH3 | ENSCAFP00000051611 | ENSCAFP00000023739 | Uncharacterized protein. | Notch receptor 3. | 0.942 |
| ADAM17 | NUMB | ENSCAFP00000051611 | ENSCAFP00000024755 | Uncharacterized protein. | NUMB endocytic adaptor protein. | 0.551 |
| ADAM17 | PSEN1 | ENSCAFP00000051611 | ENSCAFP00000024732 | Uncharacterized protein. | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels. Stimulates cell-cell adhesion via its interaction with CDH1; this stabili [...] | 0.620 |
| ADAM17 | PSEN2 | ENSCAFP00000051611 | ENSCAFP00000060221 | Uncharacterized protein. | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. | 0.501 |
| ADAM17 | PSENEN | ENSCAFP00000051611 | ENSCAFP00000039072 | Uncharacterized protein. | Presenilin enhancer, gamma-secretase subunit. | 0.483 |
| AKT1 | EGFR | ENSCAFP00000027133 | ENSCAFP00000005164 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Receptor protein-tyrosine kinase. | 0.441 |
| AKT1 | GSK3B | ENSCAFP00000027133 | ENSCAFP00000034412 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. | 0.951 |
| AKT1 | LCK | ENSCAFP00000027133 | ENSCAFP00000015667 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Tyrosine-protein kinase. | 0.656 |
| AKT1 | MAPK1 | ENSCAFP00000027133 | ENSCAFP00000030998 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.927 |
| AKT1 | PIK3R1 | ENSCAFP00000027133 | ENSCAFP00000011322 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.955 |
| AKT1 | PIK3R2 | ENSCAFP00000027133 | ENSCAFP00000022072 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Uncharacterized protein. | 0.924 |
| AKT1 | SKP2 | ENSCAFP00000027133 | ENSCAFP00000027621 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | S-phase kinase associated protein 2. | 0.415 |
| AKT1 | SMAD4 | ENSCAFP00000027133 | ENSCAFP00000052646 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.496 |
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