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| | ME2 | Malic enzyme. (607 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (549 aa) |
| | ACAT2 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa) |
| | MMUT | Methylmalonyl-CoA mutase. (750 aa) |
| | GCK | Phosphotransferase. (226 aa) |
| | DLD | Dihydrolipoyl dehydrogenase, mitochondrial; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched- chain amino acid-dehydrogenase complex). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT [...] (509 aa) |
| | GLUD1-2 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (490 aa) |
| | HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa) |
| | ME3 | Malic enzyme. (692 aa) |
| | SUCLA2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (433 aa) |
| | PCCA | Propionyl-CoA carboxylase subunit alpha. (731 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (406 aa) |
| | IDH3B | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa) |
| | SUCLG2 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (451 aa) |
| | OGDHL | Oxoglutarate dehydrogenase like. (1006 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells. (528 aa) |
| | GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (560 aa) |
| | PDHB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa) |
| | SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa) |
| | HK2 | Hexokinase 2. (930 aa) |
| | GOT2 | Aspartate aminotransferase. (430 aa) |
| | PFKM | ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (853 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | HIBCH | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa) |
| | HAO2 | Hydroxyacid oxidase 2. (389 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa) |
| | PFKL | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa) |
| | PRPS2 | Phosphoribosyl pyrophosphate synthetase 2. (318 aa) |
| | LOC607355 | Aminotran_5 domain-containing protein. (463 aa) |
| | SDHC | Succinate dehydrogenase complex subunit C. (271 aa) |
| | EHHADH | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa) |
| | ECHS1 | Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa) |
| | RPE | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa) |
| | HK1 | Hexokinase 1. (935 aa) |
| | DLAT | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa) |
| | IDH3A | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa) |
| | ACOX3 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa) |
| | TPI1 | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (286 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) |
| | PGLS | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (258 aa) |
| | FH | Fumarate hydratase. (508 aa) |
| | SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) |
| | HK3 | Hexokinase 3. (953 aa) |
| | PGD | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (480 aa) |
| | PGK1 | Phosphoglycerate kinase. (417 aa) |
| | LOC100683724 | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | ADPGK | ADP dependent glucokinase. (495 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa) |
| | IDH3G | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa) |
| | TKTL1 | Transketolase like 1. (596 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (624 aa) |
| | ENO1 | Enolase 1. (191 aa) |
| | GCSH | Glycine cleavage system protein H. (306 aa) |
| | ME1 | Malic enzyme. (563 aa) |
| | LOC608055 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (572 aa) |
| | ACADS | Acyl-CoA dehydrogenase short chain. (396 aa) |
| | AMT | Aminomethyltransferase, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (403 aa) |
| | ALDOA | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (416 aa) |
| | MDH1 | Malate dehydrogenase. (334 aa) |
| | LOC106558132 | Glyceraldehyde-3-phosphate dehydrogenase. (368 aa) |
| | RGN | Regucalcin. (299 aa) |
| | ALDOC | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa) |
| | LOC100688969 | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (433 aa) |
| | HKDC1 | Hexokinase domain containing 1. (917 aa) |
| | LOC106560188 | Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (358 aa) |
| | LOC106558049 | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | RPIA | Uncharacterized protein. (311 aa) |
| | ENO4 | Enolase 4. (624 aa) |
| | MDH2-2 | Malate dehydrogenase. (347 aa) |
| | ALDH6A1 | Aldehyde dehydrogenase 6 family member A1. (543 aa) |
| | LOC477441 | Glyceraldehyde-3-phosphate dehydrogenase. (334 aa) |
| | ACO1 | Aconitase 1; Belongs to the aconitase/IPM isomerase family. (901 aa) |
| | GLYCTK | Glycerate kinase. (523 aa) |
| | TALDO1 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa) |
| | TKT | Transketolase. (705 aa) |
| | TKFC | Triokinase and FMN cyclase. (593 aa) |
| | FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (363 aa) |
| | ENO3 | Enolase 3. (489 aa) |
| | CS | Citrate synthase; Belongs to the citrate synthase family. (493 aa) |
| | ACO2 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (816 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1532 aa) |
| | ALDOB | Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (381 aa) |
| | GLDC | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1032 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (590 aa) |
| | ENO2 | Enolase 2. (566 aa) |
| | ESD | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa) |
| | ACOX1 | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (735 aa) |
| | SDSL | Serine dehydratase like. (396 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (824 aa) |
| | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (405 aa) |
| | ENSCAFP00000056413 | Pribosyltran_N domain-containing protein. (401 aa) |
| | PFKP | Phosphofructokinase, platelet. (870 aa) |
| | LOC100855679 | Aminotran_5 domain-containing protein. (537 aa) |
| | SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (734 aa) |
| | PGAM2 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (296 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (900 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (749 aa) |
| | IDNK | IDNK gluconokinase. (354 aa) |
| | PKLR | Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family. (640 aa) |
| | DLST | Dihydrolipoamide S-succinyltransferase. (652 aa) |
| | PGK2 | Phosphoglycerate kinase. (448 aa) |
| | IDH2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (441 aa) |
| | PC | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1206 aa) |
| | LOC475755 | Uncharacterized protein. (239 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (391 aa) |
| | OGDH | Transket_pyr domain-containing protein. (998 aa) |
| | PKM | Multifunctional fusion protein; Belongs to the pyruvate kinase family. (1112 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (734 aa) |
