Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARAF | GRB2 | ENSCAFP00000022298 | ENSCAFP00000049390 | A-Raf proto-oncogene, serine/threonine kinase. | Growth factor receptor bound protein 2. | 0.526 |
| ARAF | HRAS | ENSCAFP00000022298 | ENSCAFP00000040726 | A-Raf proto-oncogene, serine/threonine kinase. | Uncharacterized protein. | 0.960 |
| ARAF | MAP2K1 | ENSCAFP00000022298 | ENSCAFP00000045279 | A-Raf proto-oncogene, serine/threonine kinase. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.964 |
| ARAF | MAP2K2 | ENSCAFP00000022298 | ENSCAFP00000043510 | A-Raf proto-oncogene, serine/threonine kinase. | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (By similarity). | 0.966 |
| ARAF | MAPK1 | ENSCAFP00000022298 | ENSCAFP00000030998 | A-Raf proto-oncogene, serine/threonine kinase. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.653 |
| ARAF | NRAS | ENSCAFP00000022298 | ENSCAFP00000014016 | A-Raf proto-oncogene, serine/threonine kinase. | Uncharacterized protein. | 0.972 |
| ARAF | PIK3CB | ENSCAFP00000022298 | ENSCAFP00000011245 | A-Raf proto-oncogene, serine/threonine kinase. | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. | 0.516 |
| ARAF | PRKCA | ENSCAFP00000022298 | ENSCAFP00000016686 | A-Raf proto-oncogene, serine/threonine kinase. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.903 |
| ARAF | PRKCB | ENSCAFP00000022298 | ENSCAFP00000025992 | A-Raf proto-oncogene, serine/threonine kinase. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.903 |
| ARAF | PRKCG | ENSCAFP00000022298 | ENSCAFP00000003976 | A-Raf proto-oncogene, serine/threonine kinase. | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.903 |
| ARAF | RAF1 | ENSCAFP00000022298 | ENSCAFP00000007376 | A-Raf proto-oncogene, serine/threonine kinase. | Raf-1 proto-oncogene, serine/threonine kinase. | 0.903 |
| BID | CASP3 | ENSCAFP00000052515 | ENSCAFP00000011475 | BH3 interacting domain death agonist. | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | 0.641 |
| BID | FAS | ENSCAFP00000052515 | ENSCAFP00000023091 | BH3 interacting domain death agonist. | Fas cell surface death receptor. | 0.620 |
| BID | FASLG | ENSCAFP00000052515 | ENSCAFP00000021643 | BH3 interacting domain death agonist. | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. | 0.535 |
| CASP3 | BID | ENSCAFP00000011475 | ENSCAFP00000052515 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | BH3 interacting domain death agonist. | 0.641 |
| CASP3 | CSF2 | ENSCAFP00000011475 | ENSCAFP00000032076 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. | 0.426 |
| CASP3 | FAS | ENSCAFP00000011475 | ENSCAFP00000023091 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Fas cell surface death receptor. | 0.682 |
| CASP3 | FASLG | ENSCAFP00000011475 | ENSCAFP00000021643 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Tumor necrosis factor ligand 1A; Belongs to the tumor necrosis factor family. | 0.730 |
| CASP3 | ICAM1 | ENSCAFP00000011475 | ENSCAFP00000026375 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Intercellular adhesion molecule 1; ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity). Belongs to the immunoglobulin superfamily. ICAM family. | 0.597 |
| CASP3 | IFNG | ENSCAFP00000011475 | ENSCAFP00000000588 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. | 0.737 |
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