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| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | SHC3 | SHC adaptor protein 3. (458 aa) |
| | RHOQ | Ras homolog family member Q. (126 aa) |
| | CALM2 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | GCK | Phosphotransferase. (226 aa) |
| | GYS1 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (735 aa) |
| | MKNK1 | MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (421 aa) |
| | F1PIN6_CANLF | Uncharacterized protein; Belongs to the calmodulin family. (364 aa) |
| | PIK3R3 | Uncharacterized protein. (461 aa) |
| | PYGB | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (950 aa) |
| | LIPE | Lipase E, hormone sensitive type. (1097 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (545 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (597 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | CALML5 | Calmodulin like 5. (169 aa) |
| | AKT2 | AKT serine/threonine kinase 2. (557 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1264 aa) |
| | FOXO1 | Forkhead box O1. (654 aa) |
| | FASN | Fatty acid synthase. (2478 aa) |
| | IRS2 | Insulin receptor substrate 2. (1382 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | SOCS2 | Suppressor of cytokine signaling 2. (299 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1353 aa) |
| | PPP1R3B | Protein phosphatase 1 regulatory subunit. (378 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (725 aa) |
| | HK2 | Hexokinase 2. (930 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | NRAS | Uncharacterized protein. (189 aa) |
| | CBLB | Cbl proto-oncogene B. (1004 aa) |
| | PHKG1 | Phosphorylase kinase catalytic subunit gamma 1. (530 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2431 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (443 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin de [...] (330 aa) |
| | G6PC2 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (794 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (399 aa) |
| | GYS2 | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa) |
| | PPP1R3D | Protein phosphatase 1 regulatory subunit. (299 aa) |
| | HK1 | Hexokinase 1. (935 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1375 aa) |
| | PYGM | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa) |
| | PYGL | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (870 aa) |
| | E2RL59_CANLF | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (270 aa) |
| | G6PC | Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity). (357 aa) |
| | SHC4 | SHC adaptor protein 4. (632 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa) |
| | PIK3R2 | Uncharacterized protein. (726 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (605 aa) |
| | ELK1 | ETS transcription factor ELK1. (515 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PPP1R3F | Protein phosphatase 1 regulatory subunit 3F. (812 aa) |
| | HK3 | Hexokinase 3. (953 aa) |
| | EIF4E1B | Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (234 aa) |
| | PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2647 aa) |
| | SHC1 | SHC adaptor protein 1. (577 aa) |
| | CALML4 | Calmodulin like 4. (120 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | IRS4 | Insulin receptor substrate 4. (1275 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1147 aa) |
| | TRIP10 | Thyroid hormone receptor interactor 10. (634 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (197 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (532 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (385 aa) |
| | CALML6 | Calmodulin like 6. (156 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa) |
| | MKNK2 | MAPK interacting serine/threonine kinase 2. (352 aa) |
| | SHC2 | Uncharacterized protein. (636 aa) |
| | PIK3CD | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta; Belongs to the PI3/PI4-kinase family. (1083 aa) |
| | TSC1 | TSC complex subunit 1. (1169 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (397 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Dephosphorylates RPS6KB1. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density- asso [...] (499 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (354 aa) |
| | HKDC1 | Hexokinase domain containing 1. (917 aa) |
| | RPS6KB2 | Non-specific serine/threonine protein kinase. (510 aa) |
| | LOC100685282 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (262 aa) |
| | TSC2 | TSC complex subunit 2. (1783 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1406 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | PHKA1 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1239 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | PPP1R3C | Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (317 aa) |
| | SH2B2 | SH2B adaptor protein 2. (626 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (By similarity). (442 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (478 aa) |
| | FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (363 aa) |
| | CBL | Cbl proto-oncogene. (895 aa) |
| | EIF4E2 | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (238 aa) |
| | PHKB | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1153 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (385 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (250 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (275 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (232 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (891 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (573 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (337 aa) |
| | EIF4E | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (246 aa) |
| | INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (232 aa) |
| | PHKA2 | Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1335 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (551 aa) |
| | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...] (350 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (485 aa) |
| | RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1297 aa) |
| | FLOT1 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (429 aa) |
| | PPP1R3A | Protein phosphatase 1 regulatory subunit 3A. (1084 aa) |
| | INPP5A | Inositol polyphosphate-5-phosphatase A; Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. (430 aa) |
| | PTPRF | Protein tyrosine phosphatase receptor type F. (1927 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (427 aa) |
| | PKLR | Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family. (640 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (553 aa) |
| | PDE3B | Phosphodiesterase. (1069 aa) |
