(6 nodes) Repression of WNT target genes network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLE4	Transducin-like enhancer protein 4 isoform X2. (711 aa)
	TCF7L1	Transcription factor 7-like 1. (567 aa)
	CTBP2	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	CTBP1	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (422 aa)
	TCF7	LOW QUALITY PROTEIN: transcription factor 7. (517 aa)
	TLE1	Transducin-like enhancer protein 1. (714 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP1	CTBP2	ENSVVUP00000017768	ENSVVUP00000007910	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.932
CTBP1	TCF7	ENSVVUP00000017768	ENSVVUP00000029284	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	LOW QUALITY PROTEIN: transcription factor 7.	0.770
CTBP1	TCF7L1	ENSVVUP00000017768	ENSVVUP00000002948	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7-like 1.	0.977
CTBP1	TLE1	ENSVVUP00000017768	ENSVVUP00000033854	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 1.	0.480
CTBP1	TLE4	ENSVVUP00000017768	ENSVVUP00000001748	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 4 isoform X2.	0.440
CTBP2	CTBP1	ENSVVUP00000007910	ENSVVUP00000017768	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.932
CTBP2	TCF7	ENSVVUP00000007910	ENSVVUP00000029284	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	LOW QUALITY PROTEIN: transcription factor 7.	0.574
CTBP2	TCF7L1	ENSVVUP00000007910	ENSVVUP00000002948	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7-like 1.	0.969
CTBP2	TLE1	ENSVVUP00000007910	ENSVVUP00000033854	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 1.	0.493
CTBP2	TLE4	ENSVVUP00000007910	ENSVVUP00000001748	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 4 isoform X2.	0.440
TCF7	CTBP1	ENSVVUP00000029284	ENSVVUP00000017768	LOW QUALITY PROTEIN: transcription factor 7.	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.770
TCF7	CTBP2	ENSVVUP00000029284	ENSVVUP00000007910	LOW QUALITY PROTEIN: transcription factor 7.	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.574
TCF7	TLE1	ENSVVUP00000029284	ENSVVUP00000033854	LOW QUALITY PROTEIN: transcription factor 7.	Transducin-like enhancer protein 1.	0.680
TCF7	TLE4	ENSVVUP00000029284	ENSVVUP00000001748	LOW QUALITY PROTEIN: transcription factor 7.	Transducin-like enhancer protein 4 isoform X2.	0.624
TCF7L1	CTBP1	ENSVVUP00000002948	ENSVVUP00000017768	Transcription factor 7-like 1.	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.977
TCF7L1	CTBP2	ENSVVUP00000002948	ENSVVUP00000007910	Transcription factor 7-like 1.	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.969
TCF7L1	TLE1	ENSVVUP00000002948	ENSVVUP00000033854	Transcription factor 7-like 1.	Transducin-like enhancer protein 1.	0.711
TCF7L1	TLE4	ENSVVUP00000002948	ENSVVUP00000001748	Transcription factor 7-like 1.	Transducin-like enhancer protein 4 isoform X2.	0.624
TLE1	CTBP1	ENSVVUP00000033854	ENSVVUP00000017768	Transducin-like enhancer protein 1.	C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.480
TLE1	CTBP2	ENSVVUP00000033854	ENSVVUP00000007910	Transducin-like enhancer protein 1.	C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.493