(12 nodes) ESCRT I complex, and ESCRT II complex network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TSG101	LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein. (373 aa)
	SNF8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	VPS37C	Vacuolar protein sorting-associated protein 37C isoform X1. (379 aa)
	VPS28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
	VPS37A	Vacuolar protein sorting-associated protein 37A isoform X1. (396 aa)
	MVB12B	Multivesicular body subunit 12B isoform X2. (306 aa)
	MVB12A	Multivesicular body subunit 12A isoform X1. (298 aa)
	UBAP1	LOW QUALITY PROTEIN: ubiquitin-associated protein 1. (466 aa)
	VPS25	Vacuolar protein-sorting-associated protein 25. (176 aa)
	ENSVVUP00000036810	annotation not available (68 aa)
	VPS36	Vacuolar protein-sorting-associated protein 36 isoform X2. (367 aa)
	VPS37B	Vacuolar protein sorting-associated protein 37B. (332 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVVUP00000036810	MVB12A	ENSVVUP00000036810	ENSVVUP00000021912	annotation not available	Multivesicular body subunit 12A isoform X1.	0.935
ENSVVUP00000036810	MVB12B	ENSVVUP00000036810	ENSVVUP00000013967	annotation not available	Multivesicular body subunit 12B isoform X2.	0.929
ENSVVUP00000036810	SNF8	ENSVVUP00000036810	ENSVVUP00000004362	annotation not available	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.637
ENSVVUP00000036810	UBAP1	ENSVVUP00000036810	ENSVVUP00000028744	annotation not available	LOW QUALITY PROTEIN: ubiquitin-associated protein 1.	0.819
ENSVVUP00000036810	VPS25	ENSVVUP00000036810	ENSVVUP00000033010	annotation not available	Vacuolar protein-sorting-associated protein 25.	0.771
ENSVVUP00000036810	VPS28	ENSVVUP00000036810	ENSVVUP00000007862	annotation not available	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.990
ENSVVUP00000036810	VPS36	ENSVVUP00000036810	ENSVVUP00000037450	annotation not available	Vacuolar protein-sorting-associated protein 36 isoform X2.	0.914
ENSVVUP00000036810	VPS37A	ENSVVUP00000036810	ENSVVUP00000010035	annotation not available	Vacuolar protein sorting-associated protein 37A isoform X1.	0.909
ENSVVUP00000036810	VPS37B	ENSVVUP00000036810	ENSVVUP00000039430	annotation not available	Vacuolar protein sorting-associated protein 37B.	0.960
ENSVVUP00000036810	VPS37C	ENSVVUP00000036810	ENSVVUP00000006512	annotation not available	Vacuolar protein sorting-associated protein 37C isoform X1.	0.828
MVB12A	ENSVVUP00000036810	ENSVVUP00000021912	ENSVVUP00000036810	Multivesicular body subunit 12A isoform X1.	annotation not available	0.935
MVB12A	MVB12B	ENSVVUP00000021912	ENSVVUP00000013967	Multivesicular body subunit 12A isoform X1.	Multivesicular body subunit 12B isoform X2.	0.678
MVB12A	SNF8	ENSVVUP00000021912	ENSVVUP00000004362	Multivesicular body subunit 12A isoform X1.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.684
MVB12A	TSG101	ENSVVUP00000021912	ENSVVUP00000003418	Multivesicular body subunit 12A isoform X1.	LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein.	0.935
MVB12A	UBAP1	ENSVVUP00000021912	ENSVVUP00000028744	Multivesicular body subunit 12A isoform X1.	LOW QUALITY PROTEIN: ubiquitin-associated protein 1.	0.843
MVB12A	VPS25	ENSVVUP00000021912	ENSVVUP00000033010	Multivesicular body subunit 12A isoform X1.	Vacuolar protein-sorting-associated protein 25.	0.852
MVB12A	VPS28	ENSVVUP00000021912	ENSVVUP00000007862	Multivesicular body subunit 12A isoform X1.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.993
MVB12A	VPS36	ENSVVUP00000021912	ENSVVUP00000037450	Multivesicular body subunit 12A isoform X1.	Vacuolar protein-sorting-associated protein 36 isoform X2.	0.829
MVB12A	VPS37A	ENSVVUP00000021912	ENSVVUP00000010035	Multivesicular body subunit 12A isoform X1.	Vacuolar protein sorting-associated protein 37A isoform X1.	0.957
MVB12A	VPS37B	ENSVVUP00000021912	ENSVVUP00000039430	Multivesicular body subunit 12A isoform X1.	Vacuolar protein sorting-associated protein 37B.	0.987