(17 nodes) Mixed, incl. Relaxin receptors, and R-spondin, Fu-CRD domain network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LGR4	Leucine-rich repeat-containing G-protein coupled receptor 4. (955 aa)
	RSPO3	R-spondin-3 isoform X1. (279 aa)
	LGR6	Leucine-rich repeat-containing G-protein coupled receptor 6. (893 aa)
	INSL6	Insulin-like peptide INSL6. (212 aa)
	LOC112922149	Prorelaxin isoform X2. (177 aa)
	PLGRKT	Plasminogen receptor (KT). (147 aa)
	RSPO4	R-spondin-4. (371 aa)
	LGR5	Leucine-rich repeat-containing G-protein coupled receptor 5. (296 aa)
	INSL3	Insulin-like 3. (144 aa)
	RNF43	E3 ubiquitin-protein ligase RNF43. (778 aa)
	RSPO2	R-spondin-2. (243 aa)
	RXFP2	Relaxin receptor 2. (728 aa)
	RXFP1	Relaxin receptor 1. (758 aa)
	RXFP3	Relaxin-3 receptor 1. (468 aa)
	RSPO1	R-spondin-1. (265 aa)
	RLN3	Relaxin-3. (172 aa)
	RNF149	E3 ubiquitin-protein ligase RNF149. (363 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INSL3	INSL6	ENSVVUP00000014004	ENSVVUP00000009907	Insulin-like 3.	Insulin-like peptide INSL6.	0.557
INSL3	LGR4	ENSVVUP00000014004	ENSVVUP00000000623	Insulin-like 3.	Leucine-rich repeat-containing G-protein coupled receptor 4.	0.640
INSL3	LGR5	ENSVVUP00000014004	ENSVVUP00000011804	Insulin-like 3.	Leucine-rich repeat-containing G-protein coupled receptor 5.	0.640
INSL3	LGR6	ENSVVUP00000014004	ENSVVUP00000008668	Insulin-like 3.	Leucine-rich repeat-containing G-protein coupled receptor 6.	0.449
INSL3	LOC112922149	ENSVVUP00000014004	ENSVVUP00000009949	Insulin-like 3.	Prorelaxin isoform X2.	0.986
INSL3	RLN3	ENSVVUP00000014004	ENSVVUP00000037423	Insulin-like 3.	Relaxin-3.	0.935
INSL3	RXFP1	ENSVVUP00000014004	ENSVVUP00000028776	Insulin-like 3.	Relaxin receptor 1.	0.982
INSL3	RXFP2	ENSVVUP00000014004	ENSVVUP00000026835	Insulin-like 3.	Relaxin receptor 2.	0.997
INSL3	RXFP3	ENSVVUP00000014004	ENSVVUP00000030332	Insulin-like 3.	Relaxin-3 receptor 1.	0.949
INSL6	INSL3	ENSVVUP00000009907	ENSVVUP00000014004	Insulin-like peptide INSL6.	Insulin-like 3.	0.557
INSL6	LOC112922149	ENSVVUP00000009907	ENSVVUP00000009949	Insulin-like peptide INSL6.	Prorelaxin isoform X2.	0.536
INSL6	PLGRKT	ENSVVUP00000009907	ENSVVUP00000009950	Insulin-like peptide INSL6.	Plasminogen receptor (KT).	0.603
INSL6	RLN3	ENSVVUP00000009907	ENSVVUP00000037423	Insulin-like peptide INSL6.	Relaxin-3.	0.607
INSL6	RXFP1	ENSVVUP00000009907	ENSVVUP00000028776	Insulin-like peptide INSL6.	Relaxin receptor 1.	0.501
INSL6	RXFP3	ENSVVUP00000009907	ENSVVUP00000030332	Insulin-like peptide INSL6.	Relaxin-3 receptor 1.	0.547
LGR4	INSL3	ENSVVUP00000000623	ENSVVUP00000014004	Leucine-rich repeat-containing G-protein coupled receptor 4.	Insulin-like 3.	0.640
LGR4	LGR5	ENSVVUP00000000623	ENSVVUP00000011804	Leucine-rich repeat-containing G-protein coupled receptor 4.	Leucine-rich repeat-containing G-protein coupled receptor 5.	0.961
LGR4	LGR6	ENSVVUP00000000623	ENSVVUP00000008668	Leucine-rich repeat-containing G-protein coupled receptor 4.	Leucine-rich repeat-containing G-protein coupled receptor 6.	0.933
LGR4	LOC112922149	ENSVVUP00000000623	ENSVVUP00000009949	Leucine-rich repeat-containing G-protein coupled receptor 4.	Prorelaxin isoform X2.	0.608
LGR4	RLN3	ENSVVUP00000000623	ENSVVUP00000037423	Leucine-rich repeat-containing G-protein coupled receptor 4.	Relaxin-3.	0.668