(13 nodes) Mixed, incl. Insulin-like growth factor-binding protein family 1-6, chordata, and Pappalysin-1/2 network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IGFBP4	Insulin-like growth factor-binding protein 4. (258 aa)
	STC2	Stanniocalcin-2. (302 aa)
	IGFBP7	Insulin-like growth factor-binding protein 7. (183 aa)
	IGFBP5	Insulin-like growth factor-binding protein 5. (271 aa)
	IGFBP2	Insulin-like growth factor-binding protein 2. (185 aa)
	IGFALS	Insulin-like growth factor-binding protein complex acid labile subunit. (654 aa)
	PAPPA	Pappalysin-1. (1572 aa)
	PAPPA2	Pappalysin-2. (1781 aa)
	PRG2	Bone marrow proteoglycan. (260 aa)
	IGF1	Insulin-like growth factor I isoform X1. (187 aa)
	IGFBP6	Insulin-like growth factor-binding protein 6. (238 aa)
	ENSVVUP00000041494	annotation not available (120 aa)
	IGFBP1	Insulin-like growth factor-binding protein 1. (249 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVVUP00000041494	IGF1	ENSVVUP00000041494	ENSVVUP00000024480	annotation not available	Insulin-like growth factor I isoform X1.	0.992
ENSVVUP00000041494	IGFALS	ENSVVUP00000041494	ENSVVUP00000013543	annotation not available	Insulin-like growth factor-binding protein complex acid labile subunit.	0.965
ENSVVUP00000041494	IGFBP1	ENSVVUP00000041494	ENSVVUP00000041496	annotation not available	Insulin-like growth factor-binding protein 1.	0.762
ENSVVUP00000041494	IGFBP2	ENSVVUP00000041494	ENSVVUP00000010331	annotation not available	Insulin-like growth factor-binding protein 2.	0.436
ENSVVUP00000041494	IGFBP4	ENSVVUP00000041494	ENSVVUP00000000953	annotation not available	Insulin-like growth factor-binding protein 4.	0.757
ENSVVUP00000041494	IGFBP5	ENSVVUP00000041494	ENSVVUP00000010322	annotation not available	Insulin-like growth factor-binding protein 5.	0.413
ENSVVUP00000041494	IGFBP7	ENSVVUP00000041494	ENSVVUP00000007911	annotation not available	Insulin-like growth factor-binding protein 7.	0.733
IGF1	ENSVVUP00000041494	ENSVVUP00000024480	ENSVVUP00000041494	Insulin-like growth factor I isoform X1.	annotation not available	0.992
IGF1	IGFALS	ENSVVUP00000024480	ENSVVUP00000013543	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein complex acid labile subunit.	0.940
IGF1	IGFBP1	ENSVVUP00000024480	ENSVVUP00000041496	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 1.	0.994
IGF1	IGFBP2	ENSVVUP00000024480	ENSVVUP00000010331	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 2.	0.985
IGF1	IGFBP4	ENSVVUP00000024480	ENSVVUP00000000953	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 4.	0.971
IGF1	IGFBP5	ENSVVUP00000024480	ENSVVUP00000010322	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 5.	0.991
IGF1	IGFBP6	ENSVVUP00000024480	ENSVVUP00000039351	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 6.	0.986
IGF1	IGFBP7	ENSVVUP00000024480	ENSVVUP00000007911	Insulin-like growth factor I isoform X1.	Insulin-like growth factor-binding protein 7.	0.811
IGF1	PAPPA	ENSVVUP00000024480	ENSVVUP00000015573	Insulin-like growth factor I isoform X1.	Pappalysin-1.	0.600
IGF1	PAPPA2	ENSVVUP00000024480	ENSVVUP00000017696	Insulin-like growth factor I isoform X1.	Pappalysin-2.	0.450
IGFALS	ENSVVUP00000041494	ENSVVUP00000013543	ENSVVUP00000041494	Insulin-like growth factor-binding protein complex acid labile subunit.	annotation not available	0.965
IGFALS	IGF1	ENSVVUP00000013543	ENSVVUP00000024480	Insulin-like growth factor-binding protein complex acid labile subunit.	Insulin-like growth factor I isoform X1.	0.940
IGFALS	IGFBP1	ENSVVUP00000013543	ENSVVUP00000041496	Insulin-like growth factor-binding protein complex acid labile subunit.	Insulin-like growth factor-binding protein 1.	0.525