STRINGSTRING
UBE2E2 UBE2E2 SAE1 SAE1 ENSVVUP00000000469 ENSVVUP00000000469 ENSVVUP00000000682 ENSVVUP00000000682 RNF44 RNF44 UBE2Q1 UBE2Q1 WAC WAC ENSVVUP00000002517 ENSVVUP00000002517 ENSVVUP00000003072 ENSVVUP00000003072 TDP2 TDP2 ENSVVUP00000003930 ENSVVUP00000003930 UBE2Z UBE2Z RANGAP1 RANGAP1 LOC112913025 LOC112913025 C1QTNF12 C1QTNF12 MIB2 MIB2 ENSVVUP00000006033 ENSVVUP00000006033 ENSVVUP00000007041 ENSVVUP00000007041 UBA6 UBA6 ENSVVUP00000007999 ENSVVUP00000007999 LOC112921655 LOC112921655 LOC112919013 LOC112919013 LOC112928967 LOC112928967 UBQLN1 UBQLN1 UBA52 UBA52 PIAS4 PIAS4 ENSVVUP00000011053 ENSVVUP00000011053 UBE2D1 UBE2D1 SUMO3-2 SUMO3-2 ZNF451 ZNF451 SENP5 SENP5 DSPP DSPP UBE2D3 UBE2D3 TRAF7 TRAF7 ENSVVUP00000013261 ENSVVUP00000013261 RPS27A RPS27A UBE2D2 UBE2D2 UBE2I-2 UBE2I-2 UBE2J1 UBE2J1 ENSVVUP00000014764 ENSVVUP00000014764 SUMO2 SUMO2 UBE2I UBE2I UBE2A UBE2A ENSVVUP00000015831 ENSVVUP00000015831 ENSVVUP00000016091 ENSVVUP00000016091 SUMO3 SUMO3 ENSVVUP00000016420 ENSVVUP00000016420 HLTF HLTF UBE2H UBE2H STUB1 STUB1 ENSVVUP00000017554 ENSVVUP00000017554 SUMO2-2 SUMO2-2 LOC112932868 LOC112932868 ATXN3 ATXN3 ENSVVUP00000018544 ENSVVUP00000018544 ENSVVUP00000018664 ENSVVUP00000018664 UBE2U UBE2U SENP6 SENP6 UBA1 UBA1 PIAS1 PIAS1 UBE2K UBE2K UBE2O UBE2O ANKIB1 ANKIB1 UBQLN2 UBQLN2 UBQLN3 UBQLN3 LOC112911787 LOC112911787 LOC112919619 LOC112919619 UBA2 UBA2 UBE2E3 UBE2E3 ENSVVUP00000023416 ENSVVUP00000023416 ENSVVUP00000023942 ENSVVUP00000023942 UBE2V2 UBE2V2 UBE2QL1 UBE2QL1 ENSVVUP00000024657 ENSVVUP00000024657 SENP1 SENP1 SUMO1 SUMO1 ARIH1 ARIH1 CCDC197 CCDC197 RNF20 RNF20 UBE2W UBE2W ENSVVUP00000027292 ENSVVUP00000027292 RANBP2 RANBP2 ENSVVUP00000028044 ENSVVUP00000028044 UBE2L3 UBE2L3 LOC112926351 LOC112926351 UBE2Q2 UBE2Q2 UBE2R2 UBE2R2 ZFAND4 ZFAND4 UBE2B UBE2B LOC112934935 LOC112934935 ENSVVUP00000029422 ENSVVUP00000029422 SENP7 SENP7 HECTD2 HECTD2 ENSVVUP00000029828 ENSVVUP00000029828 UBE2V1 UBE2V1 LOC112917600 LOC112917600 CDC34 CDC34 UBE4B UBE4B AQP12B AQP12B RNF4 RNF4 SUMO2-3 SUMO2-3 UBE2G2 UBE2G2 NFATC2IP NFATC2IP RAD23A RAD23A LOC112910913 LOC112910913 ENSVVUP00000034103 ENSVVUP00000034103 RAD18 RAD18 UBOX5 UBOX5 ZMIZ1 ZMIZ1 UBC UBC RNF8 RNF8 UBE2G1 UBE2G1 LOC112922823 LOC112922823 RAD23B RAD23B RNF40 RNF40 LOC112921255 LOC112921255 TDP1 TDP1 RNF165 RNF165 NGLY1 NGLY1 PIAS2 PIAS2 TOP2B TOP2B UBE2E1 UBE2E1 ENSVVUP00000040094 ENSVVUP00000040094 TOP1 TOP1 UBB UBB ENSVVUP00000042833 ENSVVUP00000042833
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBE2E2Ubiquitin-conjugating enzyme E2 E2. (202 aa)
SAE1SUMO-activating enzyme subunit 1. (380 aa)
ENSVVUP00000000469annotation not available (147 aa)
ENSVVUP00000000682annotation not available (176 aa)
RNF44RING finger protein 44 isoform X2. (460 aa)
UBE2Q1Ubiquitin-conjugating enzyme E2 Q1. (455 aa)
WACWW domain-containing adapter protein with coiled-coil isoform X2. (646 aa)
ENSVVUP00000002517annotation not available (161 aa)
ENSVVUP00000003072annotation not available (119 aa)
TDP2tyrosyl-DNA phosphodiesterase 2. (180 aa)
ENSVVUP00000003930annotation not available (62 aa)
UBE2ZUbiquitin-conjugating enzyme E2 Z. (328 aa)
RANGAP1Ran GTPase-activating protein 1 isoform X1. (587 aa)
LOC112913025Ubiquitin-like. (77 aa)
C1QTNF12Adipolin. (297 aa)
MIB2E3 ubiquitin-protein ligase MIB2 isoform X1. (957 aa)
ENSVVUP00000006033annotation not available (102 aa)
ENSVVUP00000007041annotation not available (62 aa)
UBA6Ubiquitin-like modifier-activating enzyme 6 isoform X1. (1097 aa)
ENSVVUP00000007999annotation not available (96 aa)
LOC112921655Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC112919013E3 ubiquitin-protein ligase RLIM-like. (638 aa)
LOC112928967Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
UBQLN1Ubiquilin-1 isoform X1. (585 aa)
UBA52ubiquitin-60S ribosomal protein L40. (231 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (597 aa)
ENSVVUP00000011053annotation not available (235 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
SUMO3-2Small ubiquitin-related modifier 3. (52 aa)
ZNF451E3 SUMO-protein ligase ZNF451 isoform X1. (1047 aa)
SENP5Sentrin-specific protease 5 isoform X1. (754 aa)
DSPPDentin sialophosphoprotein. (362 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3. (175 aa)
TRAF7E3 ubiquitin-protein ligase TRAF7 isoform X1. (701 aa)
ENSVVUP00000013261annotation not available (158 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
UBE2I-2SUMO-conjugating enzyme UBC9; Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
UBE2J1Ubiquitin-conjugating enzyme E2 J1. (303 aa)
ENSVVUP00000014764annotation not available (139 aa)
SUMO2Small ubiquitin-related modifier 2-like isoform X2. (71 aa)
UBE2IUbiquitin-conjugating enzyme E2 I. (184 aa)
UBE2AUbiquitin-conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (173 aa)
ENSVVUP00000015831annotation not available (189 aa)
ENSVVUP00000016091annotation not available (109 aa)
SUMO3Small ubiquitin-related modifier 3. (102 aa)
ENSVVUP00000016420annotation not available (71 aa)
HLTFHelicase-like transcription factor isoform X3. (1007 aa)
UBE2HUbiquitin-conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
ENSVVUP00000017554annotation not available (71 aa)
SUMO2-2Small ubiquitin-related modifier. (104 aa)
LOC112932868Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
ATXN3Ataxin-3 isoform X7. (95 aa)
ENSVVUP00000018544annotation not available (52 aa)
ENSVVUP00000018664Small ubiquitin-related modifier 2-A-like. (80 aa)
UBE2UUbiquitin-conjugating enzyme E2 U isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (232 aa)
SENP6Sentrin-specific protease 6 isoform X1. (1115 aa)
UBA1Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
PIAS1E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa)
UBE2KUbiquitin-conjugating enzyme E2 K isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
UBE2O(E3-independent) E2 ubiquitin-conjugating enzyme isoform X1. (1140 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1092 aa)
UBQLN2Ubiquilin-2. (623 aa)
UBQLN3Ubiquilin-3. (655 aa)
LOC112911787Ubiquilin-3-like. (527 aa)
LOC112919619Placenta-specific gene 8 protein-like. (152 aa)
UBA2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (779 aa)
UBE2E3Ubiquitin-conjugating enzyme E2 E3; Belongs to the ubiquitin-conjugating enzyme family. (304 aa)
ENSVVUP00000023416Ubiquitin-conjugating enzyme E2 N-like. (105 aa)
ENSVVUP00000023942Ubiquitin-conjugating enzyme E2 N-like. (93 aa)
UBE2V2Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. (152 aa)
UBE2QL1Ubiquitin-conjugating enzyme E2Q-like protein 1. (161 aa)
ENSVVUP00000024657annotation not available (103 aa)
SENP1Sentrin-specific protease 1 isoform X1. (690 aa)
SUMO1Small ubiquitin-related modifier. (62 aa)
ARIH1RBR-type E3 ubiquitin transferase. (539 aa)
CCDC197Uncharacterized protein CCDC197. (311 aa)
RNF20E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1024 aa)
UBE2WUbiquitin-conjugating enzyme E2 W. (198 aa)
ENSVVUP00000027292Ubiquitin-conjugating enzyme E2 N-like. (146 aa)
RANBP2E3 SUMO-protein ligase RanBP2 isoform X4. (3265 aa)
ENSVVUP00000028044annotation not available (77 aa)
UBE2L3Ubiquitin-conjugating enzyme E2 L3 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC112926351Ubiquitin-conjugating enzyme E2 variant 1-like. (80 aa)
UBE2Q2Ubiquitin-conjugating enzyme E2 Q2. (358 aa)
UBE2R2Ubiquitin-conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
ZFAND4AN1-type zinc finger protein 4 isoform X1. (740 aa)
UBE2BUbiquitin-conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC112934935Small ubiquitin-related modifier. (95 aa)
ENSVVUP00000029422Ubiquitin-conjugating enzyme E2 N-like. (89 aa)
SENP7Sentrin-specific protease 7 isoform X2. (1013 aa)
HECTD2Probable E3 ubiquitin-protein ligase HECTD2. (733 aa)
ENSVVUP00000029828annotation not available (92 aa)
UBE2V1Ubiquitin-conjugating enzyme E2 variant 1 isoform X3. (105 aa)
LOC112917600Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
CDC34Ubiquitin-conjugating enzyme E2 R1; Belongs to the ubiquitin-conjugating enzyme family. (306 aa)
UBE4BUbiquitin conjugation factor E4 B isoform X3. (1339 aa)
AQP12BAquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (314 aa)
RNF4E3 ubiquitin-protein ligase RNF4. (191 aa)
SUMO2-3Small ubiquitin-related modifier 2. (120 aa)
UBE2G2Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (232 aa)
NFATC2IPNFATC2-interacting protein. (421 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (370 aa)
LOC112910913Ubiquitin-like. (77 aa)
ENSVVUP00000034103annotation not available (101 aa)
RAD18E3 ubiquitin-protein ligase RAD18. (503 aa)
UBOX5RING finger protein 37 isoform X1. (541 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1 isoform X1. (1072 aa)
UBCpolyubiquitin-C. (190 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (539 aa)
UBE2G1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (171 aa)
LOC112922823Ubiquitin-like. (77 aa)
RAD23BUV excision repair protein RAD23 homolog B. (387 aa)
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1000 aa)
LOC112921255Keratin, type II microfibrillar, component 7C-like; Belongs to the intermediate filament family. (162 aa)
TDP1tyrosyl-DNA phosphodiesterase 1. (609 aa)
RNF165E3 ubiquitin-protein ligase RNF165. (378 aa)
NGLY1peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase isoform X1. (774 aa)
PIAS2E3 SUMO-protein ligase PIAS2 isoform X2. (612 aa)
TOP2BDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1682 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
ENSVVUP00000040094annotation not available (128 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (657 aa)
UBBpolyubiquitin-B. (153 aa)
ENSVVUP00000042833annotation not available (82 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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