(5 nodes) MCM N-terminal domain, and Minichromosome maintenance proteins network (Vulpes vulpes)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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textmining

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protein homology

Your Input:
	MCM6	DNA helicase; Belongs to the MCM family. (821 aa)
	MCM4	DNA helicase; Belongs to the MCM family. (865 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (653 aa)
	MCM5	DNA helicase; Belongs to the MCM family. (763 aa)
	CDC45	Cell division control protein 45 homolog. (569 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC45	MCM4	ENSVVUP00000035259	ENSVVUP00000023909	Cell division control protein 45 homolog.	DNA helicase; Belongs to the MCM family.	0.999
CDC45	MCM5	ENSVVUP00000035259	ENSVVUP00000032458	Cell division control protein 45 homolog.	DNA helicase; Belongs to the MCM family.	0.999
CDC45	MCM6	ENSVVUP00000035259	ENSVVUP00000009534	Cell division control protein 45 homolog.	DNA helicase; Belongs to the MCM family.	0.999
CDC45	MCM7	ENSVVUP00000035259	ENSVVUP00000032124	Cell division control protein 45 homolog.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MCM4	CDC45	ENSVVUP00000023909	ENSVVUP00000035259	DNA helicase; Belongs to the MCM family.	Cell division control protein 45 homolog.	0.999
MCM4	MCM5	ENSVVUP00000023909	ENSVVUP00000032458	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM4	MCM6	ENSVVUP00000023909	ENSVVUP00000009534	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM4	MCM7	ENSVVUP00000023909	ENSVVUP00000032124	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MCM5	CDC45	ENSVVUP00000032458	ENSVVUP00000035259	DNA helicase; Belongs to the MCM family.	Cell division control protein 45 homolog.	0.999
MCM5	MCM4	ENSVVUP00000032458	ENSVVUP00000023909	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM5	MCM6	ENSVVUP00000032458	ENSVVUP00000009534	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM5	MCM7	ENSVVUP00000032458	ENSVVUP00000032124	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MCM6	CDC45	ENSVVUP00000009534	ENSVVUP00000035259	DNA helicase; Belongs to the MCM family.	Cell division control protein 45 homolog.	0.999
MCM6	MCM4	ENSVVUP00000009534	ENSVVUP00000023909	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM6	MCM5	ENSVVUP00000009534	ENSVVUP00000032458	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM6	MCM7	ENSVVUP00000009534	ENSVVUP00000032124	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MCM7	CDC45	ENSVVUP00000032124	ENSVVUP00000035259	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Cell division control protein 45 homolog.	0.999
MCM7	MCM4	ENSVVUP00000032124	ENSVVUP00000023909	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MCM5	ENSVVUP00000032124	ENSVVUP00000032458	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
MCM7	MCM6	ENSVVUP00000032124	ENSVVUP00000009534	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999