STRINGSTRING
EIF4E3 EIF4E3 EIF4G3 EIF4G3 EIF4E2 EIF4E2 EIF3D EIF3D EIF4E-2 EIF4E-2 LSM1 LSM1 DCPS DCPS NCBP1 NCBP1 ENSVVUP00000020147 ENSVVUP00000020147 AGO2 AGO2 LOC112916519 LOC112916519 ENSVVUP00000015198 ENSVVUP00000015198 NCBP2L NCBP2L NCBP2 NCBP2 ENSVVUP00000011053 ENSVVUP00000011053 EIF4E EIF4E LARP1 LARP1 GEMIN5 GEMIN5 LOC112928517 LOC112928517 EIF4E1B EIF4E1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4E3Eukaryotic translation initiation factor 4E type 3 isoform X2; Belongs to the eukaryotic initiation factor 4E family. (142 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3 isoform X6. (1745 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family. (250 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (563 aa)
EIF4E-2Eukaryotic translation initiation factor 4E isoform X1; Belongs to the eukaryotic initiation factor 4E family. (222 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
DCPSm7GpppX diphosphatase. (388 aa)
NCBP1Nuclear cap-binding protein subunit 1 isoform X1. (790 aa)
ENSVVUP00000020147annotation not available (94 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (813 aa)
LOC112916519Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
ENSVVUP00000015198annotation not available (200 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (141 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
ENSVVUP00000011053annotation not available (235 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family. (302 aa)
LARP1La-related protein 1 isoform X1. (895 aa)
GEMIN5Gem-associated protein 5 isoform X1. (1508 aa)
LOC112928517Eukaryotic translation initiation factor 4E type 2-like isoform X2; Belongs to the eukaryotic initiation factor 4E family. (200 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (241 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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