(19 nodes) Formation of translation preinitiation complex network (Vulpes vulpes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	ENSVVUP00000000375	annotation not available (252 aa)
	EIF5	Eukaryotic translation initiation factor 5. (430 aa)
	LOC112912280	Eukaryotic translation initiation factor 2 subunit 3, X-linked-like isoform X1. (469 aa)
	EIF2S2	Eukaryotic translation initiation factor 2 subunit 2. (348 aa)
	LOC112933756	Malignant T-cell-amplified sequence. (207 aa)
	EIF2S3	Eukaryotic translation initiation factor 2 subunit 3. (472 aa)
	EIF2D	Eukaryotic translation initiation factor 2D isoform X2. (583 aa)
	EIF4B	Eukaryotic translation initiation factor 4B isoform X1. (581 aa)
	ENSVVUP00000028365	annotation not available (145 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1367 aa)
	LOC112927932-2	Eukaryotic translation initiation factor 2 subunit 2-like. (269 aa)
	ENSVVUP00000033256	annotation not available (64 aa)
	EIF4H	Eukaryotic translation initiation factor 4H. (312 aa)
	LOC112927932	Eukaryotic translation initiation factor 2 subunit 2-like. (304 aa)
	ENSVVUP00000039325	annotation not available (175 aa)
	EIF4B-2	Eukaryotic translation initiation factor 4B isoform X1. (364 aa)
	DENR	Density-regulated protein; Belongs to the DENR family. (275 aa)
	MCTS1	MCTS1 re-initiation and release factor. (163 aa)
	LOC112928080	Malignant T-cell-amplified sequence. (189 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENR	EIF2D	ENSVVUP00000039447	ENSVVUP00000018360	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2D isoform X2.	0.743
DENR	EIF2S2	ENSVVUP00000039447	ENSVVUP00000005796	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2 subunit 2.	0.658
DENR	EIF2S3	ENSVVUP00000039447	ENSVVUP00000017265	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2 subunit 3.	0.557
DENR	EIF4H	ENSVVUP00000039447	ENSVVUP00000034390	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 4H.	0.492
DENR	EIF5	ENSVVUP00000039447	ENSVVUP00000000534	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 5.	0.767
DENR	ENSVVUP00000028365	ENSVVUP00000039447	ENSVVUP00000028365	Density-regulated protein; Belongs to the DENR family.	annotation not available	0.557
DENR	LOC112912280	ENSVVUP00000039447	ENSVVUP00000005245	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2 subunit 3, X-linked-like isoform X1.	0.557
DENR	LOC112927932	ENSVVUP00000039447	ENSVVUP00000036231	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2 subunit 2-like.	0.658
DENR	LOC112927932-2	ENSVVUP00000039447	ENSVVUP00000029768	Density-regulated protein; Belongs to the DENR family.	Eukaryotic translation initiation factor 2 subunit 2-like.	0.658
DENR	LOC112928080	ENSVVUP00000039447	ENSVVUP00000039987	Density-regulated protein; Belongs to the DENR family.	Malignant T-cell-amplified sequence.	0.877
DENR	LOC112933756	ENSVVUP00000039447	ENSVVUP00000010333	Density-regulated protein; Belongs to the DENR family.	Malignant T-cell-amplified sequence.	0.877
DENR	MCTS1	ENSVVUP00000039447	ENSVVUP00000039496	Density-regulated protein; Belongs to the DENR family.	MCTS1 re-initiation and release factor.	0.877
DHX29	EIF4B	ENSVVUP00000029196	ENSVVUP00000022149	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 4B isoform X1.	0.425
DHX29	EIF4B-2	ENSVVUP00000029196	ENSVVUP00000039331	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 4B isoform X1.	0.425
DHX29	EIF4H	ENSVVUP00000029196	ENSVVUP00000034390	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 4H.	0.467
DHX29	EIF5	ENSVVUP00000029196	ENSVVUP00000000534	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 5.	0.631
DHX29	ENSVVUP00000000375	ENSVVUP00000029196	ENSVVUP00000000375	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	annotation not available	0.425
DHX29	ENSVVUP00000033256	ENSVVUP00000029196	ENSVVUP00000033256	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	annotation not available	0.425
DHX29	ENSVVUP00000039325	ENSVVUP00000029196	ENSVVUP00000039325	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	annotation not available	0.425
EIF2D	DENR	ENSVVUP00000018360	ENSVVUP00000039447	Eukaryotic translation initiation factor 2D isoform X2.	Density-regulated protein; Belongs to the DENR family.	0.743