STRINGSTRING
HOXC13 HOXC13 APCDD1 APCDD1 SAV1 SAV1 LGR4 LGR4 WNT10A WNT10A NOM1 NOM1 LDB1 LDB1 FZD3 FZD3 NGFR NGFR ERCC2 ERCC2 DLX3 DLX3 TRPC4AP TRPC4AP ZMPSTE24 ZMPSTE24 TMEM79 TMEM79 NSDHL NSDHL INHBA INHBA EDA EDA TNFRSF19 TNFRSF19 PIAS4 PIAS4 LGR5 LGR5 SOSTDC1 SOSTDC1 SOX9 SOX9 LHX2 LHX2 INTU INTU SMO SMO TGFB2 TGFB2 TP63 TP63 CD109 CD109 PUM2 PUM2 NF1 NF1 LDB2 LDB2 EXT1 EXT1 FGF7 FGF7 FOXN1 FOXN1 NSUN2 NSUN2 SOS1 SOS1 KRT17 KRT17 PLA2G10 PLA2G10 EDAR EDAR SNAI1 SNAI1 ZDHHC21 ZDHHC21 KRT27 KRT27 KRT26 KRT26 KRT25 KRT25 CELSR1 CELSR1 GORAB GORAB FGF10 FGF10 FST FST NOTCH1 NOTCH1 LRP4 LRP4 RELA RELA ALX4 ALX4 DSG4 DSG4 ACVR1B ACVR1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXC13LOW QUALITY PROTEIN: homeobox protein Hox-C13. (214 aa)
APCDD1Protein APCDD1 isoform X1. (498 aa)
SAV1Protein salvador homolog 1. (351 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (955 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
NOM1Nucleolar MIF4G domain-containing protein 1 isoform X2. (863 aa)
LDB1LIM domain-binding protein 1 isoform X3. (411 aa)
FZD3Frizzled-3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
NGFRTumor necrosis factor receptor superfamily member 16. (423 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD isoform X1. (760 aa)
DLX3Homeobox protein DLX-3. (287 aa)
TRPC4APShort transient receptor potential channel 4-associated protein isoform X1. (797 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (473 aa)
TMEM79Transmembrane protein 79. (395 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X2; Belongs to the 3-beta-HSD family. (361 aa)
INHBAInhibin beta A chain. (424 aa)
EDAectodysplasin-A; Belongs to the tumor necrosis factor family. (259 aa)
TNFRSF19Tumor necrosis factor receptor superfamily member 19. (415 aa)
PIAS4E3 SUMO-protein ligase PIAS4. (597 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5. (296 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
SOX9LOW QUALITY PROTEIN: transcription factor SOX-9. (445 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
INTUProtein inturned isoform X2. (940 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (802 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (676 aa)
CD109CD109 antigen. (1445 aa)
PUM2Pumilio homolog 2 isoform X2. (1063 aa)
NF1Neurofibromin. (2816 aa)
LDB2LIM domain-binding protein 2 isoform X1. (373 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (537 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FOXN1Forkhead box protein N1. (645 aa)
NSUN2tRNA (Cytosine(34)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (712 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
KRT17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (433 aa)
PLA2G10Phospholipase A(2). (152 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (479 aa)
SNAI1Zinc finger protein SNAI1 isoform X1. (264 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
KRT27Keratin, type I cytoskeletal 27 isoform X1. (446 aa)
KRT26Keratin, type I cytoskeletal 26-like; Belongs to the intermediate filament family. (464 aa)
KRT25Keratin, type I cytoskeletal 25; Belongs to the intermediate filament family. (450 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2741 aa)
GORABRAB6-interacting golgin isoform X1. (397 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
FSTFollistatin isoform X1. (344 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2644 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1883 aa)
RELATranscription factor p65 isoform X2. (542 aa)
ALX4Homeobox protein aristaless-like 4. (376 aa)
DSG4Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1058 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (538 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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