STRINGSTRING
TNS4 TNS4 FOCAD FOCAD ZFYVE21 ZFYVE21 GRB7 GRB7 NRP1 NRP1 ITGB1 ITGB1 GFRAL GFRAL KLF11 KLF11 CPNE3 CPNE3 LASP1 LASP1 PTK2B PTK2B ACTN1 ACTN1 NEDD9 NEDD9 VASP VASP PGM5 PGM5 PPFIA1 PPFIA1 TLNRD1 TLNRD1 PALLD PALLD RSU1 RSU1 SORBS3 SORBS3 ITGB3 ITGB3 MAPRE1-2 MAPRE1-2 RALA RALA XIRP1 XIRP1 DST DST IQGAP1 IQGAP1 ACTB ACTB ENSVVUP00000008444 ENSVVUP00000008444 FES FES WASF1 WASF1 RHOU RHOU ENSVVUP00000008924 ENSVVUP00000008924 EZR EZR ENSVVUP00000009373 ENSVVUP00000009373 ANXA6 ANXA6 ITGB5 ITGB5 LMLN LMLN TNS1 TNS1 ENSVVUP00000010497 ENSVVUP00000010497 SYNPO2 SYNPO2 ITGB8 ITGB8 LIMS2 LIMS2 ITGAV ITGAV PIK3R2 PIK3R2 ACTN2 ACTN2 ATAT1 ATAT1 CAV1 CAV1 TES TES TLN2 TLN2 MAPRE1 MAPRE1 PRUNE1 PRUNE1 IL1RL1 IL1RL1 SORBS2 SORBS2 ENSVVUP00000017517 ENSVVUP00000017517 IRF2 IRF2 SH3KBP1 SH3KBP1 LPP LPP ALKBH6 ALKBH6 LOC112923751 LOC112923751 ENSVVUP00000018607 ENSVVUP00000018607 LOC112909181 LOC112909181 GSN GSN ARHGAP24 ARHGAP24 FLRT3 FLRT3 ITGB4 ITGB4 PTK2 PTK2 ITGA11 ITGA11 CORO2B CORO2B LIMS1 LIMS1 NPHS1 NPHS1 SRP68 SRP68 ZYX ZYX ARL14EP ARL14EP XIRP2 XIRP2 LPXN LPXN CASS4 CASS4 ENSVVUP00000024290 ENSVVUP00000024290 ITGA2B ITGA2B SENP1 SENP1 SHROOM4 SHROOM4 ITGB6 ITGB6 SLA SLA ACTG1 ACTG1 ENSVVUP00000026390 ENSVVUP00000026390 ARL14EPL ARL14EPL DLC1 DLC1 PRAG1 PRAG1 PEAK1 PEAK1 AJUBA AJUBA EFS EFS MAPK1 MAPK1 TNFSF13B TNFSF13B PXN PXN GIT1 GIT1 ARHGAP26 ARHGAP26 ENSVVUP00000028823 ENSVVUP00000028823 MTF2 MTF2 TEK TEK SLC6A4 SLC6A4 ACTBL2 ACTBL2 BCAR3 BCAR3 MSN MSN SORBS1 SORBS1 VCL VCL FERMT1 FERMT1 TLN1 TLN1 PAK1 PAK1 TRIP6 TRIP6 BCAR1 BCAR1 ITGA5 ITGA5 ILK ILK LIMA1 LIMA1 LIMK1 LIMK1 ENSVVUP00000034938 ENSVVUP00000034938 PARVA PARVA REXO2 REXO2 UBOX5 UBOX5 PTPRA PTPRA ITGA1 ITGA1 ITGA2 ITGA2 ENSVVUP00000035680 ENSVVUP00000035680 TM4SF20 TM4SF20 MAPK3 MAPK3 PDLIM7 PDLIM7 DCAF6 DCAF6 AFAP1 AFAP1 ACTN3 ACTN3 TADA1 TADA1 THSD1 THSD1 ASAP3 ASAP3 INPP5E INPP5E ATP6V0A2 ATP6V0A2 ARL2 ARL2 MAPRE2 MAPRE2 TNS2 TNS2 ITGB7 ITGB7 ALOX15B ALOX15B LCP1 LCP1 PARVG PARVG PARVB PARVB ENSVVUP00000040212 ENSVVUP00000040212 SYNE2 SYNE2 ARMC5 ARMC5 TGFB1I1 TGFB1I1 FBLIM1 FBLIM1 EPHA2 EPHA2 DAG1 DAG1 ACTL8 ACTL8 SRC SRC TNS3 TNS3 PTPRC PTPRC FERMT2 FERMT2 USP33 USP33 NEXN NEXN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNS4Tensin-4. (708 aa)
FOCADFocadhesin isoform X1. (1960 aa)
ZFYVE21Zinc finger FYVE domain-containing protein 21 isoform X1. (297 aa)
GRB7Growth factor receptor-bound protein 7 isoform X2. (491 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
GFRALLOW QUALITY PROTEIN: GDNF family receptor alpha-like. (394 aa)
KLF11Krueppel-like factor 11 isoform X1. (518 aa)
CPNE3Copine-3. (533 aa)
LASP1LIM and SH3 domain protein 1. (318 aa)
PTK2BProtein-tyrosine kinase 2-beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ACTN1Alpha-actinin-1. (913 aa)
NEDD9Enhancer of filamentation 1 isoform X2. (834 aa)
VASPVasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (350 aa)
PGM5Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (567 aa)
PPFIA1Liprin-alpha-1 isoform X4. (1257 aa)
TLNRD1Talin rod domain-containing protein 1. (342 aa)
PALLDPalladin. (1329 aa)
RSU1Ras suppressor protein 1 isoform X1. (364 aa)
SORBS3Sorbin and SH3 domain containing 3. (944 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
MAPRE1-2Microtubule-associated protein RP/EB family member 1. (126 aa)
RALARas-related protein Ral-A. (206 aa)
XIRP1Xin actin-binding repeat-containing protein 1. (1797 aa)
DSTDystonin isoform X1. (3771 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1627 aa)
ACTBActin beta. (276 aa)
ENSVVUP00000008444annotation not available (146 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (852 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (553 aa)
RHOURho-related GTP-binding protein RhoU. (342 aa)
ENSVVUP00000008924annotation not available (159 aa)
EZREzrin isoform X1. (575 aa)
ENSVVUP00000009373annotation not available (154 aa)
ANXA6Annexin. (742 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (838 aa)
LMLNLeishmanolysin-like peptidase. (692 aa)
TNS1Tensin-1 isoform X2. (1936 aa)
ENSVVUP00000010497annotation not available (2626 aa)
SYNPO2Synaptopodin-2. (1270 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (782 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (387 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1054 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (735 aa)
ACTN2Alpha-actinin-2 isoform X1. (649 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (427 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TESTestin. (412 aa)
TLN2Talin-2 isoform X2. (2556 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (195 aa)
PRUNE1Exopolyphosphatase PRUNE1 isoform X1. (453 aa)
IL1RL1Interleukin-1 receptor-like 1. (557 aa)
SORBS2Sorbin and SH3 domain-containing protein 2 isoform X11. (1200 aa)
ENSVVUP00000017517annotation not available (118 aa)
IRF2Interferon regulatory factor. (349 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X5. (665 aa)
LPPLipoma-preferred partner. (627 aa)
ALKBH6Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform X2. (238 aa)
LOC112923751Integrin beta-like protein 1. (270 aa)
ENSVVUP00000018607annotation not available (146 aa)
LOC112909181LOW QUALITY PROTEIN: PDZ and LIM domain protein 7-like. (419 aa)
GSNGelsolin isoform X1. (1236 aa)
ARHGAP24Rho GTPase-activating protein 24 isoform X1. (700 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3. (649 aa)
ITGB4Integrin beta. (1805 aa)
PTK2Focal adhesion kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1059 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1123 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (475 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
NPHS1Nephrin. (1281 aa)
SRP68Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (622 aa)
ZYXZyxin. (578 aa)
ARL14EPARL14 effector protein. (259 aa)
XIRP2LOW QUALITY PROTEIN: xin actin-binding repeat-containing protein 2. (1024 aa)
LPXNLeupaxin isoform X1; Belongs to the paxillin family. (386 aa)
CASS4Cas scaffolding protein family member 4. (809 aa)
ENSVVUP00000024290annotation not available (257 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1037 aa)
SENP1Sentrin-specific protease 1 isoform X1. (690 aa)
SHROOM4Protein Shroom4 isoform X1. (1526 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
SLASrc-like-adapter isoform X1. (315 aa)
ACTG1LOW QUALITY PROTEIN: actin, cytoplasmic 2. (364 aa)
ENSVVUP00000026390annotation not available (67 aa)
ARL14EPLARL14 effector protein-like. (152 aa)
DLC1Rho GTPase-activating protein 7 isoform X1. (1526 aa)
PRAG1Inactive tyrosine-protein kinase PRAG1. (1428 aa)
PEAK1LOW QUALITY PROTEIN: inactive tyrosine-protein kinase PEAK1. (709 aa)
AJUBALIM domain-containing protein ajuba isoform X1. (548 aa)
EFSEmbryonal Fyn-associated substrate isoform X3. (682 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
TNFSF13BTumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (417 aa)
PXNPaxillin. (1079 aa)
GIT1ARF GTPase-activating protein GIT1. (798 aa)
ARHGAP26Rho GTPase-activating protein 26 isoform X2. (770 aa)
ENSVVUP00000028823annotation not available (332 aa)
MTF2Metal-response element-binding transcription factor 2 isoform X1. (599 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (637 aa)
ACTBL2Beta-actin-like protein 2 isoform X1. (376 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (850 aa)
MSNMoesin. (577 aa)
SORBS1Sorbin and SH3 domain-containing protein 1 isoform X4. (921 aa)
VCLVinculin isoform X2. (1134 aa)
FERMT1Fermitin family homolog 1. (677 aa)
TLN1Talin-1 isoform X1. (2562 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
TRIP6Thyroid receptor-interacting protein 6. (484 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X2. (964 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (972 aa)
ILKIntegrin-linked protein kinase. (508 aa)
LIMA1LIM domain and actin-binding protein 1 isoform X3. (762 aa)
LIMK1LIM domain kinase 1 isoform X1. (714 aa)
ENSVVUP00000034938annotation not available (125 aa)
PARVAAlpha-parvin. (360 aa)
REXO2Oligoribonuclease, mitochondrial. (253 aa)
UBOX5RING finger protein 37 isoform X1. (541 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1143 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1155 aa)
ENSVVUP00000035680annotation not available (126 aa)
TM4SF20Transmembrane 4 L6 family member 20. (227 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
PDLIM7PDZ and LIM domain protein 7 isoform X5. (209 aa)
DCAF6DDB1- and CUL4-associated factor 6 isoform X3. (878 aa)
AFAP1Actin filament-associated protein 1 isoform X4. (818 aa)
ACTN3Alpha-actinin-3 isoform X1. (1024 aa)
TADA1Transcriptional adapter 1. (361 aa)
THSD1Thrombospondin type-1 domain-containing protein 1. (712 aa)
ASAP3LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3. (878 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (626 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (854 aa)
ARL2ADP-ribosylation factor-like protein 2 isoform X3; Belongs to the small GTPase superfamily. Arf family. (184 aa)
MAPRE2Microtubule-associated protein RP/EB family member 2 isoform X1. (493 aa)
TNS2Tensin-2. (1060 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (878 aa)
ALOX15BArachidonate 15-lipoxygenase B isoform X1. (667 aa)
LCP1Plastin-2 isoform X2. (736 aa)
PARVGGamma-parvin. (332 aa)
PARVBBeta-parvin. (390 aa)
ENSVVUP00000040212annotation not available (169 aa)
SYNE2Nesprin-2 isoform X2. (6932 aa)
ARMC5Armadillo repeat-containing protein 5 isoform X1. (944 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (447 aa)
FBLIM1Filamin-binding LIM protein 1. (372 aa)
EPHA2Ephrin type-A receptor 2. (921 aa)
DAG1Dystroglycan. (892 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (383 aa)
SRCTyrosine-protein kinase. (536 aa)
TNS3Tensin-3 isoform X1. (1703 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C isoform X2. (1153 aa)
FERMT2Fermitin family homolog 2 isoform X1. (792 aa)
USP33Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (912 aa)
NEXNNexilin isoform X1. (676 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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