node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GPHN | MOCOS | ENSVVUP00000000291 | ENSVVUP00000038830 | Gephyrin isoform X2. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.949 |
GPHN | MOCS1 | ENSVVUP00000000291 | ENSVVUP00000037179 | Gephyrin isoform X2. | Molybdenum cofactor biosynthesis protein 1 isoform X2. | 0.880 |
GPHN | MOCS2 | ENSVVUP00000000291 | ENSVVUP00000035677 | Gephyrin isoform X2. | Molybdenum cofactor synthesis 2. | 0.443 |
GPHN | MOCS2-2 | ENSVVUP00000000291 | ENSVVUP00000009697 | Gephyrin isoform X2. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.956 |
GPHN | MOCS3 | ENSVVUP00000000291 | ENSVVUP00000030776 | Gephyrin isoform X2. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.647 |
MOCOS | GPHN | ENSVVUP00000038830 | ENSVVUP00000000291 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Gephyrin isoform X2. | 0.949 |
MOCOS | MOCS1 | ENSVVUP00000038830 | ENSVVUP00000037179 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Molybdenum cofactor biosynthesis protein 1 isoform X2. | 0.688 |
MOCOS | MOCS2-2 | ENSVVUP00000038830 | ENSVVUP00000009697 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.550 |
MOCOS | MOCS3 | ENSVVUP00000038830 | ENSVVUP00000030776 | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.666 |
MOCS1 | GPHN | ENSVVUP00000037179 | ENSVVUP00000000291 | Molybdenum cofactor biosynthesis protein 1 isoform X2. | Gephyrin isoform X2. | 0.880 |
MOCS1 | MOCOS | ENSVVUP00000037179 | ENSVVUP00000038830 | Molybdenum cofactor biosynthesis protein 1 isoform X2. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.688 |
MOCS1 | MOCS2 | ENSVVUP00000037179 | ENSVVUP00000035677 | Molybdenum cofactor biosynthesis protein 1 isoform X2. | Molybdenum cofactor synthesis 2. | 0.628 |
MOCS1 | MOCS2-2 | ENSVVUP00000037179 | ENSVVUP00000009697 | Molybdenum cofactor biosynthesis protein 1 isoform X2. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.958 |
MOCS1 | MOCS3 | ENSVVUP00000037179 | ENSVVUP00000030776 | Molybdenum cofactor biosynthesis protein 1 isoform X2. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.657 |
MOCS2 | GPHN | ENSVVUP00000035677 | ENSVVUP00000000291 | Molybdenum cofactor synthesis 2. | Gephyrin isoform X2. | 0.443 |
MOCS2 | MOCS1 | ENSVVUP00000035677 | ENSVVUP00000037179 | Molybdenum cofactor synthesis 2. | Molybdenum cofactor biosynthesis protein 1 isoform X2. | 0.628 |
MOCS2 | MOCS2-2 | ENSVVUP00000035677 | ENSVVUP00000009697 | Molybdenum cofactor synthesis 2. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.734 |
MOCS2 | MOCS3 | ENSVVUP00000035677 | ENSVVUP00000030776 | Molybdenum cofactor synthesis 2. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.442 |
MOCS2-2 | GPHN | ENSVVUP00000009697 | ENSVVUP00000000291 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | Gephyrin isoform X2. | 0.956 |
MOCS2-2 | MOCOS | ENSVVUP00000009697 | ENSVVUP00000038830 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. | 0.550 |