STRINGSTRING
LRMP LRMP PYGO1 PYGO1 AHCTF1 AHCTF1 CHMP4C CHMP4C ENSVVUP00000001699 ENSVVUP00000001699 LOC112923559 LOC112923559 PYGO2 PYGO2 DYRK3 DYRK3 WBP2NL WBP2NL SPAG4 SPAG4 LMNB2 LMNB2 NOLC1 NOLC1 DMPK DMPK CHMP2A CHMP2A NUP153 NUP153 LOC112912956 LOC112912956 CHMP1A CHMP1A DCTN1 DCTN1 BEND3 BEND3 SUN5 SUN5 CHMP7 CHMP7 ZMPSTE24 ZMPSTE24 FSHR FSHR LMNA LMNA ENSVVUP00000007761 ENSVVUP00000007761 PLK1 PLK1 NUP155 NUP155 WDR73 WDR73 NUP205 NUP205 REEP4 REEP4 NUP133 NUP133 ANKLE2 ANKLE2 SYNE1 SYNE1 ENSVVUP00000009941 ENSVVUP00000009941 TSSK6 TSSK6 TNP1 TNP1 ENSVVUP00000010358 ENSVVUP00000010358 PSME4 PSME4 NSFL1C NSFL1C ENSVVUP00000011137 ENSVVUP00000011137 NECTIN2 NECTIN2 SPAST SPAST TOR1AIP1 TOR1AIP1 USPL1 USPL1 RTN4 RTN4 NUP107 NUP107 SYCP1 SYCP1 SUN3 SUN3 BIN1 BIN1 DMRTC2 DMRTC2 EMG1 EMG1 TPR TPR COIL COIL LEMD3 LEMD3 SEH1L SEH1L TMF1 TMF1 GALK1 GALK1 LOC112920802 LOC112920802 UBXN2A UBXN2A ENSVVUP00000020247 ENSVVUP00000020247 RBM48 RBM48 SERBP1 SERBP1 USP50 USP50 NUP35 NUP35 VPS4A VPS4A SMARCA5 SMARCA5 ENSVVUP00000023879 ENSVVUP00000023879 VPS4B VPS4B USP36 USP36 UBXN2B UBXN2B TNP2 TNP2 SYCP3 SYCP3 TMEM43 TMEM43 PML PML CHMP6 CHMP6 ENSVVUP00000025582 ENSVVUP00000025582 TBPL1 TBPL1 CHMP2B CHMP2B NEMP1 NEMP1 LOC112923335 LOC112923335 LOC112921225 LOC112921225 SIRT1 SIRT1 ETS1 ETS1 FAM118B FAM118B AKAP8L AKAP8L CHEK1 CHEK1 CHMP5 CHMP5 BAZ2A BAZ2A NUP93 NUP93 PAFAH1B1 PAFAH1B1 MFSD14A MFSD14A GOLM1 GOLM1 SUN2 SUN2 HABP4 HABP4 NUP54 NUP54 NOL12 NOL12 TMEM170A TMEM170A RRP8 RRP8 ENSVVUP00000034126 ENSVVUP00000034126 ZPR1 ZPR1 NUP98 NUP98 PIWIL1 PIWIL1 AGFG1 AGFG1 LEMD2 LEMD2 RNF8 RNF8 NDC1 NDC1 BANF1 BANF1 TARDBP TARDBP NEMP2 NEMP2 TOR1B TOR1B TOR1A TOR1A CTDNEP1 CTDNEP1 WEE2 WEE2 WRAP53 WRAP53 FAM118A FAM118A SF1 SF1 POLR1B POLR1B CHMP3 CHMP3 KDM3A KDM3A SUN1 SUN1 GPER1 GPER1 CHMP4A CHMP4A EMD EMD LMNB1 LMNB1 SELENOF SELENOF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRMPLymphoid-restricted membrane protein. (481 aa)
PYGO1Pygopus homolog 1. (394 aa)
AHCTF1Protein ELYS isoform X1. (2383 aa)
CHMP4CCharged multivesicular body protein 4c. (236 aa)
ENSVVUP00000001699annotation not available (80 aa)
LOC112923559Histone H3; Belongs to the histone H3 family. (136 aa)
PYGO2Pygopus homolog 2. (368 aa)
DYRK3Dual specificity tyrosine-phosphorylation-regulated kinase 3. (552 aa)
WBP2NLPostacrosomal sheath WW domain-binding protein. (301 aa)
SPAG4Sperm-associated antigen 4 protein isoform X2. (474 aa)
LMNB2lamin-B2; Belongs to the intermediate filament family. (667 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1 isoform X3. (693 aa)
DMPKMyotonin-protein kinase isoform X1. (695 aa)
CHMP2ACharged multivesicular body protein 2a isoform X2. (222 aa)
NUP153Nuclear pore complex protein Nup153. (1478 aa)
LOC112912956torsin-1B-like. (173 aa)
CHMP1ACharged multivesicular body protein 1a. (210 aa)
DCTN1Dynactin subunit 1 isoform X6. (1285 aa)
BEND3BEN domain-containing protein 3. (831 aa)
SUN5LOW QUALITY PROTEIN: SUN domain-containing protein 5. (393 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (473 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (703 aa)
LMNALamin; Belongs to the intermediate filament family. (685 aa)
ENSVVUP00000007761annotation not available (242 aa)
PLK1Serine/threonine-protein kinase PLK. (607 aa)
NUP155Nuclear pore complex protein Nup155 isoform X1. (1391 aa)
WDR73WD repeat-containing protein 73 isoform X1. (427 aa)
NUP205Nuclear pore complex protein Nup205 isoform X1. (2033 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
NUP133Nuclear pore complex protein Nup133. (1182 aa)
ANKLE2Ankyrin repeat and LEM domain-containing protein 2. (917 aa)
SYNE1Nesprin-1. (2833 aa)
ENSVVUP00000009941annotation not available (1578 aa)
TSSK6Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa)
TNP1Spermatid nuclear transition protein 1. (55 aa)
ENSVVUP00000010358annotation not available (181 aa)
PSME4Proteasome activator complex subunit 4. (1823 aa)
NSFL1CNSFL1 cofactor p47. (348 aa)
ENSVVUP00000011137annotation not available (69 aa)
NECTIN2Nectin-2 isoform X1. (541 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (540 aa)
TOR1AIP1torsin-1A-interacting protein 1 isoform X1. (792 aa)
USPL1SUMO-specific isopeptidase USPL1 isoform X1. (1093 aa)
RTN4Reticulon. (993 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (927 aa)
SYCP1Synaptonemal complex protein 1 isoform X1. (915 aa)
SUN3SUN domain-containing protein 3. (358 aa)
BIN1Myc box-dependent-interacting protein 1 isoform X1. (610 aa)
DMRTC2Doublesex- and mab-3-related transcription factor C2. (372 aa)
EMG1Ribosomal RNA small subunit methyltransferase NEP1. (244 aa)
TPRNucleoprotein TPR. (2511 aa)
COILCoilin. (578 aa)
LEMD3Inner nuclear membrane protein Man1. (731 aa)
SEH1LNucleoporin SEH1 isoform X3; Belongs to the WD repeat SEC13 family. (478 aa)
TMF1TATA element modulatory factor. (1025 aa)
GALK1Galactokinase. (513 aa)
LOC112920802Histone H3.3. (136 aa)
UBXN2AUBX domain-containing protein 2A. (258 aa)
ENSVVUP00000020247annotation not available (119 aa)
RBM48RNA-binding protein 48 isoform X2. (367 aa)
SERBP1Plasminogen activator inhibitor 1 RNA-binding protein isoform X3. (392 aa)
USP50Inactive ubiquitin carboxyl-terminal hydrolase 50; Belongs to the peptidase C19 family. (355 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (356 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (518 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa)
ENSVVUP00000023879annotation not available (195 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (461 aa)
USP36Ubiquitin carboxyl-terminal hydrolase 36 isoform X1; Belongs to the peptidase C19 family. (1117 aa)
UBXN2BUBX domain-containing protein 2B. (330 aa)
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (237 aa)
SYCP3Synaptonemal complex protein 3. (235 aa)
TMEM43Transmembrane protein 43. (400 aa)
PMLProtein PML. (406 aa)
CHMP6Charged multivesicular body protein 6. (184 aa)
ENSVVUP00000025582annotation not available (89 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
CHMP2BCharged multivesicular body protein 2b. (221 aa)
NEMP1Nuclear envelope integral membrane protein 1. (370 aa)
LOC112923335Histone H3; Belongs to the histone H3 family. (136 aa)
LOC112921225Testis-specific H1 histone. (287 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (769 aa)
ETS1Protein C-ets-1 isoform X2. (485 aa)
FAM118BProtein FAM118B isoform X2. (350 aa)
AKAP8LA-kinase anchor protein 8-like isoform X1; Belongs to the AKAP95 family. (648 aa)
CHEK1Serine/threonine-protein kinase Chk1; Belongs to the protein kinase superfamily. (476 aa)
CHMP5Charged multivesicular body protein 5. (288 aa)
BAZ2ABromodomain adjacent to zinc finger domain protein 2A isoform X1. (1899 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
MFSD14AHippocampus abundant transcript 1 protein. (731 aa)
GOLM1Golgi membrane protein 1 isoform X1. (406 aa)
SUN2SUN domain-containing protein 2 isoform X1. (725 aa)
HABP4Intracellular hyaluronan-binding protein 4 isoform X2. (409 aa)
NUP54Nucleoporin p54 isoform X2. (508 aa)
NOL12Nucleolar protein 12. (213 aa)
TMEM170ATransmembrane protein 170A isoform X1. (144 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (470 aa)
ENSVVUP00000034126annotation not available (114 aa)
ZPR1Zinc finger protein ZPR1. (460 aa)
NUP98Nuclear pore complex protein Nup98-Nup96 isoform X2. (1800 aa)
PIWIL1Piwi-like protein 1; Belongs to the argonaute family. (951 aa)
AGFG1arf-GAP domain and FG repeat-containing protein 1. (591 aa)
LEMD2LEM domain-containing protein 2 isoform X2. (329 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (539 aa)
NDC1Nucleoporin NDC1. (816 aa)
BANF1Barrier-to-autointegration factor. (89 aa)
TARDBPTAR DNA-binding protein 43 isoform X1. (452 aa)
NEMP2LOW QUALITY PROTEIN: nuclear envelope integral membrane protein 2. (407 aa)
TOR1BTorsin. (379 aa)
TOR1ATorsin. (332 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (226 aa)
WEE2Wee1-like protein kinase. (566 aa)
WRAP53Telomerase Cajal body protein 1 isoform X2. (539 aa)
FAM118AProtein FAM118A isoform X2. (382 aa)
SF1Splicing factor 1 isoform X9. (548 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
CHMP3Charged multivesicular body protein 3 isoform X2. (249 aa)
KDM3ALysine-specific demethylase 3A. (1322 aa)
SUN1SUN domain-containing protein 1 isoform X2. (981 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (384 aa)
CHMP4ACharged multivesicular body protein 4a isoform X2. (222 aa)
EMDEmerin. (317 aa)
LMNB1lamin-B1 isoform X1; Belongs to the intermediate filament family. (586 aa)
SELENOFSelenoprotein F. (166 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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