STRINGSTRING
CYP26B1 CYP26B1 DLL1 DLL1 PDZD7 PDZD7 GSDME GSDME LRRC1 LRRC1 MED1 MED1 UGCG UGCG FOSL2 FOSL2 RIPOR2 RIPOR2 TSG101 TSG101 ANXA1 ANXA1 KCNQ1 KCNQ1 LOC112912822 LOC112912822 ENSVVUP00000004499 ENSVVUP00000004499 WHRN WHRN GATA6 GATA6 ERCC2 ERCC2 DLX3 DLX3 PALLD PALLD DSP DSP LATS1 LATS1 JAG2 JAG2 TMEM79 TMEM79 PPP1R18 PPP1R18 GRXCR1 GRXCR1 MCOLN3 MCOLN3 SAV1 SAV1 BMP4 BMP4 TPRN TPRN TGM1 TGM1 EPHA2 EPHA2 KAZN KAZN ENSVVUP00000040567 ENSVVUP00000040567 BCL11B BCL11B SLC4A7 SLC4A7 KRT8 KRT8 KRT78 KRT78 KRT79 KRT79 KRT4 KRT4 KRT3 KRT3 KRT76 KRT76 LOC112921008 LOC112921008 KRT77 KRT77 KRT73 KRT73 KRT72 KRT72 KRT74 KRT74 KRT71 KRT71 KRT5 KRT5 KRT6A KRT6A LOC112920999 LOC112920999 KRT75 KRT75 LOC112920998 LOC112920998 KRT82 KRT82 KRT84 KRT84 KRT85 KRT85 LOC112921256 LOC112921256 LOC112920994 LOC112920994 LOC112920993 LOC112920993 LOC112920992 LOC112920992 LOC112921255 LOC112921255 KRT7 KRT7 KRT80 KRT80 KEL KEL DSG4 DSG4 CLIC4 CLIC4 HES5 HES5 OVOL1 OVOL1 ACER1 ACER1 NOTCH1 NOTCH1 OPN3 OPN3 ENSVVUP00000036810 ENSVVUP00000036810 PNPLA1 PNPLA1 LHFPL5 LHFPL5 TGM3 TGM3 KCNMA1 KCNMA1 HES1 HES1 KRT10 KRT10 FA2H FA2H USH1C USH1C PLS1 PLS1 POU3F2 POU3F2 PTCH1 PTCH1 SCRIB SCRIB CSTA CSTA MADCAM1 MADCAM1 SLC44A4 SLC44A4 PLEC PLEC PAFAH1B1 PAFAH1B1 CASP14 CASP14 SPINK5 SPINK5 IFT74 IFT74 GRXCR2 GRXCR2 TMEM132E TMEM132E ADAM9 ADAM9 ST14 ST14 BCR BCR KRT17 KRT17 KRT16 KRT16 STK4 STK4 GLI1 GLI1 SEC24B SEC24B ENSVVUP00000023631 ENSVVUP00000023631 WNT16 WNT16 FOXN1 FOXN1 EZH2 EZH2 PAX6 PAX6 MYO6 MYO6 JAG1 JAG1 LOC112907985 LOC112907985 LOC112907995 LOC112907995 ENSVVUP00000021418 ENSVVUP00000021418 ENSVVUP00000021351 ENSVVUP00000021351 CLRN2 CLRN2 EXPH5 EXPH5 CERS3 CERS3 FGF2 FGF2 TP63 TP63 USH2A USH2A CDH3 CDH3 OVOL2 OVOL2 CASP3 CASP3 WDPCP WDPCP KDF1 KDF1 SFN SFN INTU INTU CLRN1 CLRN1 YAP1 YAP1 PTPRQ PTPRQ STRC STRC ERCC3 ERCC3 SLC9A3R1 SLC9A3R1 IRF6 IRF6 CNFN CNFN PPP3CA PPP3CA ABCA12 ABCA12 PTCH2 PTCH2 FGF20 FGF20 LATS2 LATS2 TXNIP TXNIP ATOH1 ATOH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYP26B1Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (561 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
PDZD7PDZ domain-containing protein 7 isoform X1. (1019 aa)
GSDMEgasdermin-E. (495 aa)
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (619 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
UGCGCeramide glucosyltransferase. (394 aa)
FOSL2Fos-related antigen 2. (325 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1206 aa)
TSG101LOW QUALITY PROTEIN: tumor susceptibility gene 101 protein. (373 aa)
ANXA1Annexin. (345 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (690 aa)
LOC112912822Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (476 aa)
ENSVVUP00000004499annotation not available (1082 aa)
WHRNWhirlin. (847 aa)
GATA6Transcription factor GATA-6. (571 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD isoform X1. (760 aa)
DLX3Homeobox protein DLX-3. (287 aa)
PALLDPalladin. (1329 aa)
DSPDesmoplakin isoform X2. (2215 aa)
LATS1Serine/threonine-protein kinase LATS1 isoform X1. (1127 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1215 aa)
TMEM79Transmembrane protein 79. (395 aa)
PPP1R18Phostensin. (626 aa)
GRXCR1Glutaredoxin domain-containing cysteine-rich protein 1. (290 aa)
MCOLN3Mucolipin-3 isoform X1. (553 aa)
SAV1Protein salvador homolog 1. (351 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (409 aa)
TPRNTaperin. (408 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (843 aa)
EPHA2Ephrin type-A receptor 2. (921 aa)
KAZNKazrin isoform X3. (799 aa)
ENSVVUP00000040567annotation not available (177 aa)
BCL11BB-cell lymphoma/leukemia 11B. (802 aa)
SLC4A7Anion exchange protein. (1236 aa)
KRT8LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (279 aa)
KRT78Keratin, type II cytoskeletal 78; Belongs to the intermediate filament family. (545 aa)
KRT79Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. (538 aa)
KRT4Keratin, type II cytoskeletal 4; Belongs to the intermediate filament family. (527 aa)
KRT3Keratin, type II cytoskeletal 3; Belongs to the intermediate filament family. (629 aa)
KRT76Keratin, type II cytoskeletal 2 oral-like; Belongs to the intermediate filament family. (592 aa)
LOC112921008Keratin, type II cytoskeletal 3-like; Belongs to the intermediate filament family. (519 aa)
KRT77Keratin, type II cytoskeletal 1b-like; Belongs to the intermediate filament family. (586 aa)
KRT73Keratin, type II cytoskeletal 73; Belongs to the intermediate filament family. (540 aa)
KRT72Keratin, type II cytoskeletal 72; Belongs to the intermediate filament family. (510 aa)
KRT74Keratin, type II cytoskeletal 74; Belongs to the intermediate filament family. (553 aa)
KRT71Keratin, type II cytoskeletal 71 isoform X1; Belongs to the intermediate filament family. (525 aa)
KRT5Keratin, type II cytoskeletal 5; Belongs to the intermediate filament family. (591 aa)
KRT6AKeratin, type II cytoskeletal 6C; Belongs to the intermediate filament family. (564 aa)
LOC112920999Keratin, type II cytoskeletal 6A-like; Belongs to the intermediate filament family. (564 aa)
KRT75LOW QUALITY PROTEIN: keratin, type II cytoskeletal 75-like; Belongs to the intermediate filament family. (497 aa)
LOC112920998Keratin, type II cytoskeletal 5-like; Belongs to the intermediate filament family. (525 aa)
KRT82Keratin, type II cuticular Hb2; Belongs to the intermediate filament family. (509 aa)
KRT84Keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (592 aa)
KRT85Keratin, type II cuticular Hb5 isoform X1; Belongs to the intermediate filament family. (498 aa)
LOC112921256Keratin, type II cuticular Hb5-like; Belongs to the intermediate filament family. (489 aa)
LOC112920994Keratin, type II microfibrillar, component 7C; Belongs to the intermediate filament family. (487 aa)
LOC112920993Keratin, type II cuticular Hb6; Belongs to the intermediate filament family. (485 aa)
LOC112920992Keratin, type II cuticular Hb1; Belongs to the intermediate filament family. (513 aa)
LOC112921255Keratin, type II microfibrillar, component 7C-like; Belongs to the intermediate filament family. (162 aa)
KRT7Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family. (465 aa)
KRT80Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (453 aa)
KELLOW QUALITY PROTEIN: kell blood group glycoprotein. (750 aa)
DSG4Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1058 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (236 aa)
HES5Transcription factor HES-5. (139 aa)
OVOL1Putative transcription factor Ovo-like 1. (267 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2644 aa)
OPN3Opsin-3; Belongs to the G-protein coupled receptor 1 family. (419 aa)
ENSVVUP00000036810annotation not available (68 aa)
PNPLA1Patatin-like phospholipase domain-containing protein 1. (565 aa)
LHFPL5LHFPL tetraspan subfamily member 5 protein isoform X1. (313 aa)
TGM3Protein-glutamine gamma-glutamyltransferase E. (695 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X1. (1133 aa)
HES1Transcription factor HES-1. (282 aa)
KRT10LOW QUALITY PROTEIN: keratin, type I cytoskeletal 10; Belongs to the intermediate filament family. (579 aa)
FA2HFatty acid 2-hydroxylase; Belongs to the cytochrome b5 family. (369 aa)
USH1CHarmonin isoform X1. (551 aa)
PLS1Plastin-1 isoform X1. (636 aa)
POU3F2POU domain protein. (217 aa)
PTCH1Protein patched homolog 1 isoform X3. (1386 aa)
SCRIBProtein scribble homolog. (1517 aa)
CSTAcystatin-A; Belongs to the cystatin family. (93 aa)
MADCAM1Mucosal addressin cell adhesion molecule 1. (398 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (707 aa)
PLECPlectin. (4948 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CASP14Caspase-14; Belongs to the peptidase C14A family. (242 aa)
SPINK5Serine protease inhibitor Kazal-type 5. (1053 aa)
IFT74Intraflagellar transport protein 74 homolog. (600 aa)
GRXCR2Glutaredoxin domain-containing cysteine-rich protein 2. (248 aa)
TMEM132ELOW QUALITY PROTEIN: transmembrane protein 132E. (1049 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9. (819 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (832 aa)
BCRBreakpoint cluster region protein. (1367 aa)
KRT17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (433 aa)
KRT16Keratin, type I cytoskeletal 16; Belongs to the intermediate filament family. (472 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (494 aa)
GLI1Zinc finger protein GLI1. (1105 aa)
SEC24BLOW QUALITY PROTEIN: protein transport protein Sec24B. (1250 aa)
ENSVVUP00000023631annotation not available (142 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
FOXN1Forkhead box protein N1. (645 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X7. (751 aa)
PAX6Paired box protein Pax-6 isoform X2. (422 aa)
MYO6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1267 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
LOC112907985Cornifin-like. (110 aa)
LOC112907995cornifin-A. (88 aa)
ENSVVUP00000021418annotation not available (113 aa)
ENSVVUP00000021351annotation not available (591 aa)
CLRN2Clarin-2. (232 aa)
EXPH5Exophilin-5 isoform X1. (2087 aa)
CERS3Ceramide synthase 3. (396 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (676 aa)
USH2AUsherin. (5201 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (988 aa)
OVOL2Transcription factor Ovo-like 2 isoform X2. (289 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (355 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1. (724 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
INTUProtein inturned isoform X2. (940 aa)
CLRN1Clarin-1. (232 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
PTPRQPhosphatidylinositol phosphatase PTPRQ. (2308 aa)
STRCStereocilin. (1756 aa)
ERCC3General transcription and DNA repair factor IIH helicase subunit XPB. (718 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (350 aa)
IRF6Interferon regulatory factor 6. (462 aa)
CNFNCornifelin. (124 aa)
PPP3CASerine/threonine-protein phosphatase. (572 aa)
ABCA12ATP-binding cassette sub-family A member 12. (2609 aa)
PTCH2Protein patched homolog 2 isoform X2. (1207 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
LATS2Non-specific serine/threonine protein kinase. (1085 aa)
TXNIPThioredoxin-interacting protein. (391 aa)
ATOH1Protein atonal homolog 1. (359 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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