STRINGSTRING
PTPRK PTPRK MED1 MED1 ENSVVUP00000004499 ENSVVUP00000004499 ZFP36L1 ZFP36L1 ZEB1 ZEB1 ZFP36 ZFP36 LRG1 LRG1 IRF6 IRF6 YAP1 YAP1 INTU INTU STXBP4 STXBP4 CASK CASK SFN SFN KDF1 KDF1 CDH3 CDH3 TP63 TP63 SLURP1 SLURP1 CD109 CD109 FGF7 FGF7 SNAI2 SNAI2 VDR VDR IFT52 IFT52 SRSF6 SRSF6 IFT74 IFT74 IFT57 IFT57 PTCH1 PTCH1 IFT80 IFT80 FGF10 FGF10 OVOL1 OVOL1 BCL11B BCL11B TGM1 TGM1 PRKD1 PRKD1 NOTCH2 NOTCH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPRKReceptor-type tyrosine-protein phosphatase kappa isoform X8. (1430 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
ENSVVUP00000004499annotation not available (1082 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X3. (1124 aa)
ZFP36mRNA decay activator protein ZFP36. (330 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (347 aa)
IRF6Interferon regulatory factor 6. (462 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
INTUProtein inturned isoform X2. (940 aa)
STXBP4Syntaxin-binding protein 4 isoform X1. (558 aa)
CASKPeripheral plasma membrane protein CASK isoform X5; Belongs to the MAGUK family. (920 aa)
SFN14-3-3 protein sigma; Belongs to the 14-3-3 family. (248 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (988 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (676 aa)
SLURP1Secreted Ly-6/uPAR-related protein 1. (113 aa)
CD109CD109 antigen. (1445 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
VDRVitamin D3 receptor. (427 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (446 aa)
SRSF6Splicing factor, arginine/serine-rich 4/5/6. (212 aa)
IFT74Intraflagellar transport protein 74 homolog. (600 aa)
IFT57Intraflagellar transport protein 57 homolog. (429 aa)
PTCH1Protein patched homolog 1 isoform X3. (1386 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X1. (784 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
OVOL1Putative transcription factor Ovo-like 1. (267 aa)
BCL11BB-cell lymphoma/leukemia 11B. (802 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (843 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (862 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (2471 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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