(18 nodes) Positive regulation of cholesterol efflux network (Vulpes vulpes)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	APOE	Apolipoprotein E. (336 aa)
	ZDHHC8	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (759 aa)
	APOA1	Apolipoprotein A-I. (266 aa)
	ABCG4	ATP-binding cassette sub-family G member 4. (646 aa)
	PTCH1	Protein patched homolog 1 isoform X3. (1386 aa)
	ABCA7	ATP-binding cassette sub-family A member 7. (2042 aa)
	NR1H2	Oxysterols receptor LXR-beta. (457 aa)
	TREM2	Triggering receptor expressed on myeloid cells 2 isoform X1. (404 aa)
	GPS2	G protein pathway suppressor 2. (327 aa)
	EEPD1	Endonuclease/exonuclease/phosphatase family domain-containing protein 1. (569 aa)
	NR1H3	Oxysterols receptor LXR-alpha. (447 aa)
	NFKBIA	NF-kappa-B inhibitor alpha. (327 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1. (769 aa)
	PLTP	Phospholipid transfer protein. (495 aa)
	PON1	Serum paraoxonase/arylesterase 1. (355 aa)
	ADIPOQ	Adiponectin. (266 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	ABCA12	ATP-binding cassette sub-family A member 12. (2609 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA7	APOE	ENSVVUP00000031339	ENSVVUP00000011276	ATP-binding cassette sub-family A member 7.	Apolipoprotein E.	0.695
ABCA7	TREM2	ENSVVUP00000031339	ENSVVUP00000037246	ATP-binding cassette sub-family A member 7.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.723
ADIPOQ	APOE	ENSVVUP00000018002	ENSVVUP00000011276	Adiponectin.	Apolipoprotein E.	0.456
ADIPOQ	CAV1	ENSVVUP00000018002	ENSVVUP00000014366	Adiponectin.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.436
ADIPOQ	SIRT1	ENSVVUP00000018002	ENSVVUP00000027168	Adiponectin.	NAD-dependent protein deacetylase sirtuin-1.	0.505
APOA1	APOE	ENSVVUP00000034996	ENSVVUP00000011276	Apolipoprotein A-I.	Apolipoprotein E.	0.805
APOA1	PLTP	ENSVVUP00000034996	ENSVVUP00000022257	Apolipoprotein A-I.	Phospholipid transfer protein.	0.781
APOA1	PON1	ENSVVUP00000034996	ENSVVUP00000021244	Apolipoprotein A-I.	Serum paraoxonase/arylesterase 1.	0.536
APOE	ABCA7	ENSVVUP00000011276	ENSVVUP00000031339	Apolipoprotein E.	ATP-binding cassette sub-family A member 7.	0.695
APOE	ADIPOQ	ENSVVUP00000011276	ENSVVUP00000018002	Apolipoprotein E.	Adiponectin.	0.456
APOE	APOA1	ENSVVUP00000011276	ENSVVUP00000034996	Apolipoprotein E.	Apolipoprotein A-I.	0.805
APOE	CAV1	ENSVVUP00000011276	ENSVVUP00000014366	Apolipoprotein E.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.606
APOE	PLTP	ENSVVUP00000011276	ENSVVUP00000022257	Apolipoprotein E.	Phospholipid transfer protein.	0.706
APOE	PON1	ENSVVUP00000011276	ENSVVUP00000021244	Apolipoprotein E.	Serum paraoxonase/arylesterase 1.	0.708
APOE	SIRT1	ENSVVUP00000011276	ENSVVUP00000027168	Apolipoprotein E.	NAD-dependent protein deacetylase sirtuin-1.	0.436
APOE	TREM2	ENSVVUP00000011276	ENSVVUP00000037246	Apolipoprotein E.	Triggering receptor expressed on myeloid cells 2 isoform X1.	0.916
CAV1	ADIPOQ	ENSVVUP00000014366	ENSVVUP00000018002	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Adiponectin.	0.436
CAV1	APOE	ENSVVUP00000014366	ENSVVUP00000011276	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Apolipoprotein E.	0.606
GPS2	NR1H2	ENSVVUP00000039019	ENSVVUP00000027585	G protein pathway suppressor 2.	Oxysterols receptor LXR-beta.	0.503
GPS2	NR1H3	ENSVVUP00000039019	ENSVVUP00000036555	G protein pathway suppressor 2.	Oxysterols receptor LXR-alpha.	0.503