STRINGSTRING
HIF1A HIF1A SEMA4G SEMA4G NRP1 NRP1 ALDH1A2 ALDH1A2 ENSVVUP00000001699 ENSVVUP00000001699 GDNF GDNF NOLC1 NOLC1 PDCD6-2 PDCD6-2 LOC112928585 LOC112928585 EDN1 EDN1 SEMA4F SEMA4F ENSVVUP00000007731 ENSVVUP00000007731 SEMA4A SEMA4A RADIL RADIL SEMA4B SEMA4B KLHL12 KLHL12 ANXA6 ANXA6 EFNB1 EFNB1 TCOF1 TCOF1 PHOX2B PHOX2B CORO1C CORO1C FN1 FN1 SEMA6B SEMA6B ERBB4 ERBB4 EDNRA EDNRA SOX9 SOX9 ALX1 ALX1 SOX8 SOX8 KITLG KITLG SMO SMO PHACTR4 PHACTR4 SEMA6C SEMA6C ENSVVUP00000017517 ENSVVUP00000017517 SEMA6D SEMA6D KBTBD8 KBTBD8 PEF1 PEF1 JAG1 JAG1 HAND2 HAND2 NRP2 NRP2 SNAI2 SNAI2 SEMA5A SEMA5A ENSVVUP00000024290 ENSVVUP00000024290 SEMA7A SEMA7A SEMA3D SEMA3D SEMA3A SEMA3A RDH10 RDH10 SEMA6A SEMA6A SEMA3C SEMA3C MAPK1 MAPK1 ACVR1 ACVR1 RET RET CYP26C1 CYP26C1 PDCD6 PDCD6 ENSVVUP00000030161 ENSVVUP00000030161 FAM172A FAM172A SEMA4D SEMA4D SEMA5B SEMA5B SOX10 SOX10 SEMA3E SEMA3E HES1 HES1 GBX2 GBX2 HTR2B HTR2B BMPR1A BMPR1A MAPK3 MAPK3 SEMA3G SEMA3G SEMA3B SEMA3B SEMA3F SEMA3F SEMA4C SEMA4C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIF1AHypoxia-inducible factor 1-alpha. (764 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (840 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSVVUP00000001699annotation not available (80 aa)
GDNFGlial cell line-derived neurotrophic factor. (198 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1 isoform X3. (693 aa)
PDCD6-2Programmed cell death protein 6 isoform X2. (177 aa)
LOC112928585Programmed cell death protein 6-like isoform X2. (202 aa)
EDN1Endothelin-1. (202 aa)
SEMA4Fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (964 aa)
ENSVVUP00000007731annotation not available (190 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (585 aa)
RADILRas-associating and dilute domain-containing protein isoform X2. (1238 aa)
SEMA4Bsemaphorin-4B; Belongs to the semaphorin family. (954 aa)
KLHL12Kelch-like protein 12. (636 aa)
ANXA6Annexin. (742 aa)
EFNB1ephrin-B1; Belongs to the ephrin family. (436 aa)
TCOF1Treacle protein isoform X2. (1579 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (180 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
FN1Fibronectin. (2267 aa)
SEMA6BLOW QUALITY PROTEIN: semaphorin-6B; Belongs to the semaphorin family. (685 aa)
ERBB4Receptor protein-tyrosine kinase. (1249 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (426 aa)
SOX9LOW QUALITY PROTEIN: transcription factor SOX-9. (445 aa)
ALX1ALX homeobox protein 1. (326 aa)
SOX8Transcription factor SOX-8. (480 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (802 aa)
PHACTR4Phosphatase and actin regulator. (857 aa)
SEMA6CLOW QUALITY PROTEIN: semaphorin-6C; Belongs to the semaphorin family. (940 aa)
ENSVVUP00000017517annotation not available (118 aa)
SEMA6Dsemaphorin-6D isoform X1; Belongs to the semaphorin family. (1086 aa)
KBTBD8Kelch repeat and BTB domain-containing protein 8 isoform X1. (696 aa)
PEF1Peflin. (284 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (217 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
SNAI2Zinc finger protein SNAI2. (268 aa)
SEMA5Asemaphorin-5A isoform X1. (1072 aa)
ENSVVUP00000024290annotation not available (257 aa)
SEMA7Asemaphorin-7A; Belongs to the semaphorin family. (692 aa)
SEMA3Dsemaphorin-3D; Belongs to the semaphorin family. (777 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (744 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1047 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (750 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (610 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1070 aa)
CYP26C1Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (522 aa)
PDCD6Programmed cell death protein 6 isoform X1. (128 aa)
ENSVVUP00000030161annotation not available (137 aa)
FAM172AProtein FAM172A isoform X1. (470 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (854 aa)
SEMA5Bsemaphorin-5B. (1013 aa)
SOX10Transcription factor SOX-10. (468 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (722 aa)
HES1Transcription factor HES-1. (282 aa)
GBX2LOW QUALITY PROTEIN: homeobox protein GBX-2. (334 aa)
HTR2BLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 2B. (434 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
SEMA3Gsemaphorin-3G; Belongs to the semaphorin family. (765 aa)
SEMA3Bsemaphorin-3B isoform X1; Belongs to the semaphorin family. (748 aa)
SEMA3Fsemaphorin-3F isoform X1; Belongs to the semaphorin family. (791 aa)
SEMA4Csemaphorin-4C; Belongs to the semaphorin family. (833 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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