STRINGSTRING
URB2 URB2 IDH2 IDH2 CRYL1 CRYL1 SDR42E2 SDR42E2 CTBP2 CTBP2 NSDHL NSDHL SDR42E1 SDR42E1 ENSVVUP00000000610 ENSVVUP00000000610 RDH12 RDH12 LDHB LDHB ENSVVUP00000001376 ENSVVUP00000001376 DCXR DCXR LOC112920583 LOC112920583 IDH3A IDH3A PTGR1 PTGR1 ENSVVUP00000002005 ENSVVUP00000002005 LOC112926758 LOC112926758 UEVLD UEVLD LDHC LDHC LOC112911560 LOC112911560 AKR1D1 AKR1D1 LOC112927205 LOC112927205 LOC112927225 LOC112927225 ENSVVUP00000005117 ENSVVUP00000005117 CBR4 CBR4 ENSVVUP00000005985 ENSVVUP00000005985 PTGR2 PTGR2 GPD1L GPD1L FASN FASN HSD17B2 HSD17B2 HSD17B10 HSD17B10 ENSVVUP00000041793 ENSVVUP00000041793 IDH3G IDH3G G6PD G6PD DHRS7 DHRS7 AKR7L AKR7L DHRS1 DHRS1 ENSVVUP00000040957 ENSVVUP00000040957 LOC112926525 LOC112926525 LOC112926455 LOC112926455 DHRS2 DHRS2 DHRS7C DHRS7C DHRS3 DHRS3 ENSVVUP00000039754 ENSVVUP00000039754 RDH8 RDH8 KCNAB3 KCNAB3 HSD3B7 HSD3B7 RNF138 RNF138 PRXL2B PRXL2B PGD PGD KCNAB2 KCNAB2 ENSVVUP00000037023 ENSVVUP00000037023 H6PD H6PD IDH3B IDH3B ENSVVUP00000035397 ENSVVUP00000035397 HSD17B8 HSD17B8 HMGCR HMGCR HIBADH HIBADH GPD1 GPD1 ENSVVUP00000033875 ENSVVUP00000033875 LDHD LDHD HSD17B1 HSD17B1 MDH2 MDH2 HSD17B14 HSD17B14 DHDH DHDH HSD17B3 HSD17B3 RDH5 RDH5 TSTA3 TSTA3 ENSVVUP00000029569 ENSVVUP00000029569 HSD17B6 HSD17B6 SDR9C7 SDR9C7 RDH16 RDH16 ENSVVUP00000028456 ENSVVUP00000028456 CBR3 CBR3 LOC112910262 LOC112910262 LOC112910266 LOC112910266 LOC112910259 LOC112910259 GRHPR GRHPR ENSVVUP00000027198 ENSVVUP00000027198 KCNAB1 KCNAB1 ENSVVUP00000026678 ENSVVUP00000026678 ME1 ME1 HSD17B4 HSD17B4 RDH10 RDH10 ENSVVUP00000026079 ENSVVUP00000026079 ENSVVUP00000025553 ENSVVUP00000025553 ME3 ME3 ZADH2 ZADH2 ADHFE1 ADHFE1 DHRS11 DHRS11 SDR16C5 SDR16C5 ENSVVUP00000024311 ENSVVUP00000024311 KDSR KDSR DHRS13 DHRS13 HADH HADH HSD17B12 HSD17B12 HPGD HPGD DHRS9 DHRS9 HADHA HADHA ENSVVUP00000021408 ENSVVUP00000021408 ENSVVUP00000021359 ENSVVUP00000021359 RDH14 RDH14 UGDH UGDH ME2 ME2 LOC112919141 LOC112919141 ENSVVUP00000018069 ENSVVUP00000018069 AKR1B1 AKR1B1 CTBP1 CTBP1 EHHADH EHHADH MDH1 MDH1 HSD11B2 HSD11B2 MDH1B MDH1B IDH1 IDH1 SORD SORD LOC112912510 LOC112912510 ENSVVUP00000015035 ENSVVUP00000015035 ENSVVUP00000014749 ENSVVUP00000014749 LOC112916789 LOC112916789 ENSVVUP00000014676 ENSVVUP00000014676 ENSVVUP00000014155 ENSVVUP00000014155 IMPDH1 IMPDH1 HSD17B7 HSD17B7 ENSVVUP00000013076 ENSVVUP00000013076 BDH2 BDH2 HSD11B1 HSD11B1 ENSVVUP00000012614 ENSVVUP00000012614 HSD17B13 HSD17B13 HSD17B11 HSD17B11 ENSVVUP00000012244 ENSVVUP00000012244 BDH1 BDH1 DHRSX DHRSX LOC112932667 LOC112932667 LOC112932670 LOC112932670 ADH4 ADH4 ADH5 ADH5 AKR1E2 AKR1E2 LOC112933725 LOC112933725 SRD5A2 SRD5A2 RDH13 RDH13 AKR1A1 AKR1A1 SPR SPR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
URB2Unhealthy ribosome biogenesis protein 2 homolog isoform X1. (1521 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
CRYL1Lambda-crystallin homolog. (319 aa)
SDR42E2LOW QUALITY PROTEIN: putative short-chain dehydrogenase/reductase family 42E member 2. (602 aa)
CTBP2C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X2; Belongs to the 3-beta-HSD family. (361 aa)
SDR42E1Short-chain dehydrogenase/reductase family 42E member 1; Belongs to the 3-beta-HSD family. (393 aa)
ENSVVUP00000000610annotation not available (101 aa)
RDH12Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
LDHBLactate dehydrogenase B. (281 aa)
ENSVVUP00000001376annotation not available (397 aa)
DCXRL-xylulose reductase. (241 aa)
LOC112920583Carbonyl reductase [NADPH] 2-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (328 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (377 aa)
PTGR1Prostaglandin reductase 1. (329 aa)
ENSVVUP00000002005annotation not available (133 aa)
LOC112926758L-threonine 3-dehydrogenase, mitochondrial. (373 aa)
UEVLDUbiquitin-conjugating enzyme E2 variant 3 isoform X1. (648 aa)
LDHCL-lactate dehydrogenase C chain; Possible role in sperm motility. (332 aa)
LOC112911560L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
AKR1D13-oxo-5-beta-steroid 4-dehydrogenase. (302 aa)
LOC112927205Malate dehydrogenase. (338 aa)
LOC112927225L-lactate dehydrogenase B chain-like; Belongs to the LDH/MDH superfamily. (282 aa)
ENSVVUP00000005117annotation not available (85 aa)
CBR4Carbonyl reductase family member 4. (370 aa)
ENSVVUP00000005985annotation not available (221 aa)
PTGR2Prostaglandin reductase 2 isoform X1. (374 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (312 aa)
FASNFatty acid synthase. (2516 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (445 aa)
HSD17B103-hydroxyacyl-CoA dehydrogenase type-2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
ENSVVUP00000041793L-lactate dehydrogenase A chain-like. (97 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (450 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (606 aa)
DHRS7Dehydrogenase/reductase SDR family member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
AKR7LAflatoxin B1 aldehyde reductase member 2. (353 aa)
DHRS1Dehydrogenase/reductase SDR family member 1. (313 aa)
ENSVVUP00000040957annotation not available (217 aa)
LOC112926525Dehydrogenase/reductase SDR family member 4 isoform X2. (284 aa)
LOC112926455Dehydrogenase/reductase SDR family member 4 isoform X1. (305 aa)
DHRS2Dehydrogenase/reductase SDR family member 2, mitochondrial isoform X2. (281 aa)
DHRS7CDehydrogenase/reductase SDR family member 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
DHRS3Short-chain dehydrogenase/reductase 3. (365 aa)
ENSVVUP00000039754annotation not available (358 aa)
RDH8Retinol dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
KCNAB3Voltage-gated potassium channel subunit beta-3. (545 aa)
HSD3B73 beta-hydroxysteroid dehydrogenase type 7 isoform X1; Belongs to the 3-beta-HSD family. (369 aa)
RNF138E3 ubiquitin-protein ligase RNF138 isoform X1. (244 aa)
PRXL2BProstamide/prostaglandin F synthase isoform X3. (311 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
KCNAB2Voltage-gated potassium channel subunit beta-2 isoform X1. (367 aa)
ENSVVUP00000037023annotation not available (101 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein isoform X2. (797 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSVVUP00000035397annotation not available (238 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8 isoform X5. (294 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (933 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (348 aa)
ENSVVUP00000033875annotation not available (182 aa)
LDHDProbable D-lactate dehydrogenase, mitochondrial isoform X2. (485 aa)
HSD17B1Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
MDH2Malate dehydrogenase. (338 aa)
HSD17B1417-beta-hydroxysteroid dehydrogenase 14. (270 aa)
DHDHTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase. (335 aa)
HSD17B3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
RDH511-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
TSTA3GDP-L-fucose synthase. (321 aa)
ENSVVUP00000029569annotation not available (293 aa)
HSD17B617-beta-hydroxysteroid dehydrogenase type 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (331 aa)
SDR9C7Short-chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa)
RDH16Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (206 aa)
ENSVVUP00000028456annotation not available (128 aa)
CBR3Carbonyl reductase [NADPH] 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
LOC112910262Carbonyl reductase [NADPH] 1-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (292 aa)
LOC112910266Carbonyl reductase [NADPH] 1-like isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (296 aa)
LOC112910259Carbonyl reductase [NADPH] 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa)
GRHPRGlyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
ENSVVUP00000027198annotation not available (160 aa)
KCNAB1Voltage-gated potassium channel subunit beta-1 isoform X2. (556 aa)
ENSVVUP00000026678annotation not available (241 aa)
ME1Malic enzyme. (571 aa)
HSD17B4Peroxisomal multifunctional enzyme type 2. (737 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ENSVVUP00000026079annotation not available (58 aa)
ENSVVUP00000025553annotation not available (127 aa)
ME3Malic enzyme. (575 aa)
ZADH2Prostaglandin reductase 3. (449 aa)
ADHFE1Hydroxyacid-oxoacid transhydrogenase, mitochondrial. (455 aa)
DHRS11Dehydrogenase/reductase SDR family member 11 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
SDR16C5Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
ENSVVUP00000024311annotation not available (101 aa)
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (314 aa)
DHRS13Dehydrogenase/reductase SDR family member 13. (376 aa)
HADHHydroxyacyl-coenzyme A dehydrogenase, mitochondrial. (357 aa)
HSD17B12Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
DHRS9Dehydrogenase/reductase SDR family member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
HADHATrifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
ENSVVUP00000021408annotation not available (54 aa)
ENSVVUP00000021359annotation not available (58 aa)
RDH14LOW QUALITY PROTEIN: retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (429 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
ME2Malic enzyme. (584 aa)
LOC112919141L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
ENSVVUP00000018069annotation not available (234 aa)
AKR1B1Aldose reductase. (247 aa)
CTBP1C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (422 aa)
EHHADHPeroxisomal bifunctional enzyme isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
MDH1Malate dehydrogenase. (334 aa)
HSD11B2Corticosteroid 11-beta-dehydrogenase isozyme 2. (339 aa)
MDH1BPutative malate dehydrogenase 1B isoform X1. (532 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
SORDSorbitol dehydrogenase. (357 aa)
LOC1129125103-oxo-5-beta-steroid 4-dehydrogenase-like. (317 aa)
ENSVVUP00000015035annotation not available (254 aa)
ENSVVUP00000014749annotation not available (85 aa)
LOC1129167893 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Belongs to the 3-beta-HSD family. (421 aa)
ENSVVUP00000014676annotation not available (148 aa)
ENSVVUP00000014155annotation not available (85 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (487 aa)
HSD17B73-keto-steroid reductase isoform X1. (403 aa)
ENSVVUP00000013076annotation not available (106 aa)
BDH23-hydroxybutyrate dehydrogenase type 2 isoform X1. (255 aa)
HSD11B1Corticosteroid 11-beta-dehydrogenase isozyme 1 isoform X1. (293 aa)
ENSVVUP00000012614annotation not available (313 aa)
HSD17B1317-beta-hydroxysteroid dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
HSD17B11Estradiol 17-beta-dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (300 aa)
ENSVVUP00000012244annotation not available (160 aa)
BDH1D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
DHRSXDehydrogenase/reductase SDR family member on chromosome X isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (376 aa)
LOC112932667Alcohol dehydrogenase E chain. (375 aa)
LOC112932670Alcohol dehydrogenase 1-like. (375 aa)
ADH4Alcohol dehydrogenase 4. (379 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (365 aa)
AKR1E21,5-anhydro-D-fructose reductase isoform X1. (373 aa)
LOC112933725Aldo-keto reductase family 1 member C1 homolog isoform X1. (324 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (254 aa)
RDH13Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (388 aa)
AKR1A1Alcohol dehydrogenase [NADP(+)]. (325 aa)
SPRSepiapterin reductase. (267 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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