STRINGSTRING
RYR1 RYR1 ATP2A1 ATP2A1 ATP2A3 ATP2A3 BBS5 BBS5 TMEM38A TMEM38A TRDN TRDN CAMK2B CAMK2B FKBP1B FKBP1B DMPK DMPK LOC112914300 LOC112914300 CAMK2D CAMK2D CAMK2A CAMK2A ATP2A2 ATP2A2 CAMK2G CAMK2G STIM1 STIM1 ART1 ART1 PLN PLN RYR2 RYR2 REEP5 REEP5 DHRS7C DHRS7C ENSVVUP00000036743 ENSVVUP00000036743 RYR3 RYR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR1LOW QUALITY PROTEIN: ryanodine receptor 1. (4780 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1060 aa)
BBS5Kelch-like protein 41. (918 aa)
TMEM38ATrimeric intracellular cation channel type A. (299 aa)
TRDNTriadin. (136 aa)
CAMK2BCalcium/calmodulin-dependent protein kinase type II subunit beta. (633 aa)
FKBP1BPeptidylprolyl isomerase. (116 aa)
DMPKMyotonin-protein kinase isoform X1. (695 aa)
LOC112914300Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein-like isoform X1. (675 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X6. (533 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha isoform X2; Belongs to the protein kinase superfamily. (478 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (611 aa)
STIM1Stromal interaction molecule 1 isoform X2. (794 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (321 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
RYR2Ryanodine receptor 2. (4919 aa)
REEP5Receptor expression-enhancing protein 5. (351 aa)
DHRS7CDehydrogenase/reductase SDR family member 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
ENSVVUP00000036743annotation not available (110 aa)
RYR3Ryanodine receptor 3. (4847 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (28%) [HD]