20 items (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	ALX3	ALX homeobox 3. (291 aa)
	RUNX2	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (365 aa)
	HOXA9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
	HOXA11	LOW QUALITY PROTEIN: homeobox protein Hox-A11. (290 aa)
	HOXA13	Homeobox protein Hox-A13. (228 aa)
	RECK	Reversion-inducing cysteine-rich protein with Kazal motifs isoform X3. (942 aa)
	RPGRIP1L	Protein fantom. (1277 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	MSX1	Homeobox protein MSX-1. (261 aa)
	OSR1	LOW QUALITY PROTEIN: protein odd-skipped-related 1. (294 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (676 aa)
	TBX3	T-box transcription factor TBX3 isoform X1. (737 aa)
	TBX5	T-box transcription factor TBX5. (518 aa)
	TFAP2A	Transcription factor AP-2-alpha isoform X1. (439 aa)
	LNPK	Endoplasmic reticulum junction formation protein lunapark isoform X1. (429 aa)
	HOXD9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (85 aa)
	OSR2	Protein odd-skipped-related 2 isoform X2. (312 aa)
	NIPBL	Nipped-B protein. (2804 aa)
	ALDH1A2	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	ALX4	Homeobox protein aristaless-like 4. (376 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	RDH10	ENSVVUP00000001570	ENSVVUP00000026123	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family.	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.978
ALX4	RUNX2	ENSVVUP00000038247	ENSVVUP00000041121	Homeobox protein aristaless-like 4.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.405
HOXA11	HOXA9	ENSVVUP00000034305	ENSVVUP00000034312	LOW QUALITY PROTEIN: homeobox protein Hox-A11.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.449
HOXA9	HOXA11	ENSVVUP00000034312	ENSVVUP00000034305	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	LOW QUALITY PROTEIN: homeobox protein Hox-A11.	0.449
MSX1	OSR2	ENSVVUP00000020250	ENSVVUP00000016694	Homeobox protein MSX-1.	Protein odd-skipped-related 2 isoform X2.	0.490
MSX1	RUNX2	ENSVVUP00000020250	ENSVVUP00000041121	Homeobox protein MSX-1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.571
MSX1	TBX5	ENSVVUP00000020250	ENSVVUP00000017372	Homeobox protein MSX-1.	T-box transcription factor TBX5.	0.467
MSX1	TFAP2A	ENSVVUP00000020250	ENSVVUP00000005416	Homeobox protein MSX-1.	Transcription factor AP-2-alpha isoform X1.	0.706
OSR2	MSX1	ENSVVUP00000016694	ENSVVUP00000020250	Protein odd-skipped-related 2 isoform X2.	Homeobox protein MSX-1.	0.490
OSR2	RUNX2	ENSVVUP00000016694	ENSVVUP00000041121	Protein odd-skipped-related 2 isoform X2.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.475
RDH10	ALDH1A2	ENSVVUP00000026123	ENSVVUP00000001570	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family.	0.978
RUNX2	ALX4	ENSVVUP00000041121	ENSVVUP00000038247	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Homeobox protein aristaless-like 4.	0.405
RUNX2	MSX1	ENSVVUP00000041121	ENSVVUP00000020250	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Homeobox protein MSX-1.	0.571
RUNX2	OSR2	ENSVVUP00000041121	ENSVVUP00000016694	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	Protein odd-skipped-related 2 isoform X2.	0.475
TBX5	MSX1	ENSVVUP00000017372	ENSVVUP00000020250	T-box transcription factor TBX5.	Homeobox protein MSX-1.	0.467
TFAP2A	MSX1	ENSVVUP00000005416	ENSVVUP00000020250	Transcription factor AP-2-alpha isoform X1.	Homeobox protein MSX-1.	0.706