STRINGSTRING
ENSVVUP00000021885 ENSVVUP00000021885 MAP3K12 MAP3K12 MAP4K2 MAP4K2 DVL2 DVL2 MAP3K11 MAP3K11 FGD2 FGD2 TRAF2 TRAF2 FZD10 FZD10 EPHA4 EPHA4 AGER AGER RPS3 RPS3 PAK1 PAK1 PTPN1 PTPN1 SYK SYK CCL19 CCL19 TNF TNF FZD4 FZD4 ENSVVUP00000025132 ENSVVUP00000025132 TNFRSF11A TNFRSF11A ARHGEF5 ARHGEF5 MAP3K7 MAP3K7 AXIN1 AXIN1 TAOK3 TAOK3 MAP3K13 MAP3K13 DAB2IP DAB2IP DVL3 DVL3 TRAF6 TRAF6 ERN1 ERN1 ERN2 ERN2 SASH1 SASH1 EDN1 EDN1 MAP3K5 MAP3K5 MAP3K4 MAP3K4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSVVUP00000021885annotation not available (135 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
MAP4K2Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (835 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X4. (732 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (859 aa)
FGD2FYVE, RhoGEF and PH domain-containing protein 2. (728 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (986 aa)
AGERAdvanced glycosylation end product-specific receptor. (405 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (427 aa)
SYKTyrosine-protein kinase. (610 aa)
CCL19C-C motif chemokine. (272 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (486 aa)
ENSVVUP00000025132annotation not available (150 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (575 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1605 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
AXIN1Axin-1 isoform X1. (880 aa)
TAOK3Serine/threonine-protein kinase TAO3 isoform X1. (898 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1090 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X2. (747 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (991 aa)
ERN2Serine/threonine-protein kinase/endoribonuclease IRE2. (920 aa)
SASH1SAM and SH3 domain-containing protein 1 isoform X2. (1221 aa)
EDN1Endothelin-1. (202 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1350 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1511 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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