(23 nodes) Early endosome to late endosome transport network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG14	Beclin 1-associated autophagy-related key regulator. (573 aa)
	FLNA	filamin-A isoform X1. (2646 aa)
	STX8	Syntaxin-8. (319 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	HOOK1	Protein Hook homolog 1. (787 aa)
	ENSVVUP00000034315	annotation not available (59 aa)
	FAM160A2	FTS and Hook-interacting protein isoform X2. (985 aa)
	HOOK2	Protein Hook homolog 2 isoform X3. (717 aa)
	BECN1	Beclin-1 isoform X1. (471 aa)
	WDR81	WD repeat-containing protein 81 isoform X1. (1934 aa)
	RILP	Rab-interacting lysosomal protein. (357 aa)
	AKTIP	AKT-interacting protein isoform X2. (314 aa)
	RAB7A	Ras-related protein Rab-7a. (207 aa)
	EMP2	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (238 aa)
	ANKRD27	Ankyrin repeat domain-containing protein 27. (1051 aa)
	KIF16B	Kinesin-like protein KIF16B isoform X3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1349 aa)
	WDR91	WD repeat-containing protein 91 isoform X1. (746 aa)
	SNF8	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23. (1646 aa)
	PIK3R4	Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
	SNX16	Sorting nexin-16 isoform X2. (315 aa)
	HOOK3	Protein Hook homolog 3 isoform X2. (788 aa)
	RAB5A	Ras-related protein Rab-5A. (215 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKTIP	FAM160A2	ENSVVUP00000026563	ENSVVUP00000033763	AKT-interacting protein isoform X2.	FTS and Hook-interacting protein isoform X2.	0.859
AKTIP	HOOK1	ENSVVUP00000026563	ENSVVUP00000037034	AKT-interacting protein isoform X2.	Protein Hook homolog 1.	0.869
AKTIP	HOOK2	ENSVVUP00000026563	ENSVVUP00000033332	AKT-interacting protein isoform X2.	Protein Hook homolog 2 isoform X3.	0.829
AKTIP	HOOK3	ENSVVUP00000026563	ENSVVUP00000000933	AKT-interacting protein isoform X2.	Protein Hook homolog 3 isoform X2.	0.887
ANKRD27	RAB5A	ENSVVUP00000022776	ENSVVUP00000000519	Ankyrin repeat domain-containing protein 27.	Ras-related protein Rab-5A.	0.589
ATG14	BECN1	ENSVVUP00000041594	ENSVVUP00000033035	Beclin 1-associated autophagy-related key regulator.	Beclin-1 isoform X1.	0.999
ATG14	PIK3C3	ENSVVUP00000041594	ENSVVUP00000038899	Beclin 1-associated autophagy-related key regulator.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.999
ATG14	PIK3R4	ENSVVUP00000041594	ENSVVUP00000003245	Beclin 1-associated autophagy-related key regulator.	Phosphoinositide 3-kinase regulatory subunit 4.	0.999
ATG14	WDR81	ENSVVUP00000041594	ENSVVUP00000029683	Beclin 1-associated autophagy-related key regulator.	WD repeat-containing protein 81 isoform X1.	0.436
BECN1	ATG14	ENSVVUP00000033035	ENSVVUP00000041594	Beclin-1 isoform X1.	Beclin 1-associated autophagy-related key regulator.	0.999
BECN1	PIK3C3	ENSVVUP00000033035	ENSVVUP00000038899	Beclin-1 isoform X1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.999
BECN1	PIK3R4	ENSVVUP00000033035	ENSVVUP00000003245	Beclin-1 isoform X1.	Phosphoinositide 3-kinase regulatory subunit 4.	0.999
BECN1	RAB5A	ENSVVUP00000033035	ENSVVUP00000000519	Beclin-1 isoform X1.	Ras-related protein Rab-5A.	0.557
BECN1	WDR81	ENSVVUP00000033035	ENSVVUP00000029683	Beclin-1 isoform X1.	WD repeat-containing protein 81 isoform X1.	0.748
BECN1	WDR91	ENSVVUP00000033035	ENSVVUP00000007755	Beclin-1 isoform X1.	WD repeat-containing protein 91 isoform X1.	0.521
FAM160A2	AKTIP	ENSVVUP00000033763	ENSVVUP00000026563	FTS and Hook-interacting protein isoform X2.	AKT-interacting protein isoform X2.	0.859
FAM160A2	HOOK1	ENSVVUP00000033763	ENSVVUP00000037034	FTS and Hook-interacting protein isoform X2.	Protein Hook homolog 1.	0.676
FAM160A2	HOOK2	ENSVVUP00000033763	ENSVVUP00000033332	FTS and Hook-interacting protein isoform X2.	Protein Hook homolog 2 isoform X3.	0.718
FAM160A2	HOOK3	ENSVVUP00000033763	ENSVVUP00000000933	FTS and Hook-interacting protein isoform X2.	Protein Hook homolog 3 isoform X2.	0.835
HOOK1	AKTIP	ENSVVUP00000037034	ENSVVUP00000026563	Protein Hook homolog 1.	AKT-interacting protein isoform X2.	0.869