STRINGSTRING
SORT1 SORT1 SMAD3 SMAD3 JAG1 JAG1 ZFPM2 ZFPM2 DDIT3 DDIT3 ZADH2 ZADH2 CCN4 CCN4 MMP11 MMP11 WNT10B WNT10B WNT1 WNT1 SIRT1 SIRT1 C1QL4 C1QL4 TLCD3B TLCD3B FOXO1 FOXO1 GPS2 GPS2 TGFB1I1 TGFB1I1 GPER1 GPER1 FERMT2 FERMT2 FLCN FLCN ZFP36L2 ZFP36L2 TRIB2 TRIB2 LOC112921570 LOC112921570 BBS12 BBS12 AXIN1 AXIN1 ADIPOQ ADIPOQ LOC112912623 LOC112912623 WWTR1 WWTR1 YAP1 YAP1 TRIB3 TRIB3 GATA3 GATA3 SIRT2 SIRT2 TRIO TRIO JDP2 JDP2 TGFB1 TGFB1 ASXL1 ASXL1 TRPV4 TRPV4 KALRN-2 KALRN-2 ZFPM1 ZFPM1 ENPP1 ENPP1 LOC112912760 LOC112912760 RORA RORA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SORT1Sortilin. (764 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1221 aa)
ZFPM2Zinc finger protein ZFPM2. (1103 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
ZADH2Prostaglandin reductase 3. (449 aa)
CCN4WNT1-inducible-signaling pathway protein 1. (362 aa)
MMP11Stromelysin-3. (488 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (769 aa)
C1QL4Complement C1q-like protein 4. (238 aa)
TLCD3BProtein FAM57B. (304 aa)
FOXO1Forkhead box protein O1. (670 aa)
GPS2G protein pathway suppressor 2. (327 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (447 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (384 aa)
FERMT2Fermitin family homolog 2 isoform X1. (792 aa)
FLCNFolliculin. (935 aa)
ZFP36L2LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2. (601 aa)
TRIB2Tribbles homolog 2. (435 aa)
LOC112921570Ankyrin repeat domain-containing protein 26-like isoform X1. (1689 aa)
BBS12Bardet-Biedl syndrome 12 protein. (712 aa)
AXIN1Axin-1 isoform X1. (880 aa)
ADIPOQAdiponectin. (266 aa)
LOC112912623Coiled-coil domain-containing protein 144B-like. (1459 aa)
WWTR1WW domain-containing transcription regulator protein 1. (360 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
TRIB3Tribbles homolog 3. (358 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
TRIOTriple functional domain protein. (1893 aa)
JDP2Jun dimerization protein 2 isoform X1. (180 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
ASXL1Putative Polycomb group protein ASXL1 isoform X1. (1564 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
KALRN-2Kalirin isoform X8. (1293 aa)
ZFPM1Zinc finger protein ZFPM1. (703 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (932 aa)
LOC112912760Ankyrin repeat domain-containing protein 26-like. (201 aa)
RORANuclear receptor ROR-alpha. (473 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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