STRINGSTRING
CBFA2T3 CBFA2T3 CD81 CD81 RNF144B RNF144B OSBPL7 OSBPL7 FZR1 FZR1 CDKN1C CDKN1C MYLIP MYLIP SNF8 SNF8 CLU CLU NUPR1 NUPR1 GBA GBA DVL1 DVL1 ITCH ITCH CLUL1 CLUL1 CDKN1B CDKN1B NRDC NRDC USP13 USP13 DDB1 DDB1 NSF NSF CSNK1D CSNK1D RNF180 RNF180 SOCS5 SOCS5 VPS28 VPS28 PSMC4 PSMC4 PLK1 PLK1 PSMC5 PSMC5 SIRT2 SIRT2 EZR EZR AXIN2 AXIN2 SGSM3 SGSM3 HSPBP1 HSPBP1 VIP VIP SNX9 SNX9 YJEFN3 YJEFN3 NDUFA13 NDUFA13 NUB1 NUB1 ADRA2C ADRA2C CSNK2A1 CSNK2A1 SIRT6 SIRT6 TRIB3 TRIB3 APOE APOE ENSVVUP00000011482 ENSVVUP00000011482 CDC20 CDC20 RNF144A RNF144A BAG2 BAG2 ENSVVUP00000012323 ENSVVUP00000012323 DAB2IP DAB2IP ENSVVUP00000012790 ENSVVUP00000012790 ASB9 ASB9 SOX9 SOX9 DTL DTL ECSCR ECSCR GSK3A GSK3A PSMD10 PSMD10 IFNG IFNG CAV1 CAV1 USP5 USP5 AMER1 AMER1 GGA3 GGA3 TRIM32 TRIM32 TMTC3 TMTC3 DET1 DET1 APC APC ASB5 ASB5 RNFT2 RNFT2 FBXW8 FBXW8 RNF19A RNF19A ENSVVUP00000017854 ENSVVUP00000017854 OAZ3 OAZ3 BBS7 BBS7 AXIN1 AXIN1 COP1 COP1 ENSVVUP00000018409 ENSVVUP00000018409 GPC3 GPC3 ENSVVUP00000019211 ENSVVUP00000019211 SMAD7 SMAD7 PSMC2 PSMC2 PIAS1 PIAS1 MKRN2 MKRN2 ANKIB1 ANKIB1 FBXL5 FBXL5 RNF19B RNF19B DDA1 DDA1 LRRK2 LRRK2 PRICKLE1 PRICKLE1 TRIB1 TRIB1 SH3RF1 SH3RF1 SOX17 SOX17 LDLR LDLR RNFT1 RNFT1 PSMC1 PSMC1 ARIH1 ARIH1 LRP1 LRP1 NKD1 NKD1 SNX33 SNX33 FBXO22 FBXO22 TIPARP TIPARP TNF TNF SORL1 SORL1 SH3RF3 SH3RF3 BAG6 BAG6 RNF14 RNF14 NDFIP1 NDFIP1 SH3RF2 SH3RF2 CDC20B CDC20B ENSVVUP00000029378 ENSVVUP00000029378 RILP RILP CBLB CBLB RNF41 RNF41 NKD2 NKD2 ENSVVUP00000030475 ENSVVUP00000030475 LOC112913617 LOC112913617 GSK3B GSK3B LPCAT1 LPCAT1 MSN MSN TMEM259 TMEM259 LOC112908688 LOC112908688 APC2 APC2 KCNE2 KCNE2 NOP53 NOP53 HERPUD1 HERPUD1 PSMC3 PSMC3 GGA1 GGA1 FBXW9 FBXW9 RAD23A RAD23A RCHY1 RCHY1 PACSIN3 PACSIN3 TREM2 TREM2 FOXO1 FOXO1 MAPK9 MAPK9 CUL4B CUL4B TNFRSF1B TNFRSF1B IL1B IL1B DACT1 DACT1 SOCS4 SOCS4 BCAP31 BCAP31 PSMC6 PSMC6 STX5 STX5 SEC22B SEC22B C4BPB C4BPB ENSVVUP00000034315 ENSVVUP00000034315 ENSVVUP00000034799 ENSVVUP00000034799 FBXW7 FBXW7 SH3D19 SH3D19 MARCHF2 MARCHF2 DDRGK1 DDRGK1 ENSVVUP00000035544 ENSVVUP00000035544 DNAJB2 DNAJB2 RHBDD3 RHBDD3 ZER1 ZER1 ZYG11A ZYG11A NEDD4 NEDD4 TRIB2 TRIB2 PRKN PRKN PRKN-2 PRKN-2 VPS35 VPS35 DAB2 DAB2 TNFAIP3 TNFAIP3 RNF185 RNF185 ZYG11B ZYG11B GPLD1 GPLD1 OAZ1 OAZ1 ENSVVUP00000003415 ENSVVUP00000003415 RACK1 RACK1 SGTA SGTA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBFA2T3Protein CBFA2T3. (608 aa)
CD81Tetraspanin. (316 aa)
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (450 aa)
FZR1Fizzy-related protein homolog isoform X2. (571 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (165 aa)
MYLIPE3 ubiquitin-protein ligase MYLIP. (445 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (447 aa)
NUPR1Nuclear protein 1. (82 aa)
GBAGlucosylceramidase. (564 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
ITCHE3 ubiquitin-protein ligase. (1100 aa)
CLUL1Clusterin; Belongs to the clusterin family. (473 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
NRDCNardilysin isoform X2; Belongs to the peptidase M16 family. (1159 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
DDB1DNA damage-binding protein 1. (1140 aa)
NSFVesicle-fusing ATPase isoform X1. (747 aa)
CSNK1DCasein kinase I isoform X1. (412 aa)
RNF180E3 ubiquitin-protein ligase RNF180-like. (580 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (221 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PLK1Serine/threonine-protein kinase PLK. (607 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
EZREzrin isoform X1. (575 aa)
AXIN2Axin-2 isoform X1. (842 aa)
SGSM3Small G protein signaling modulator 3 isoform X1. (751 aa)
HSPBP1Hsp70-binding protein 1. (357 aa)
VIPVIP peptides isoform X1. (170 aa)
SNX9Sorting nexin. (642 aa)
YJEFN3yjeF N-terminal domain-containing protein 3 isoform X2. (345 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (218 aa)
NUB1NEDD8 ultimate buster 1. (619 aa)
ADRA2Calpha-2C adrenergic receptor. (297 aa)
CSNK2A1Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (330 aa)
TRIB3Tribbles homolog 3. (358 aa)
APOEApolipoprotein E. (336 aa)
ENSVVUP00000011482annotation not available (162 aa)
CDC20Cell division cycle protein 20 homolog. (525 aa)
RNF144ARBR-type E3 ubiquitin transferase. (302 aa)
BAG2BAG family molecular chaperone regulator 2. (211 aa)
ENSVVUP00000012323annotation not available (156 aa)
DAB2IPDisabled homolog 2-interacting protein isoform X1. (1090 aa)
ENSVVUP00000012790annotation not available (64 aa)
ASB9Ankyrin repeat and SOCS box protein 9 isoform X1. (293 aa)
SOX9LOW QUALITY PROTEIN: transcription factor SOX-9. (445 aa)
DTLDenticleless protein homolog isoform X1. (730 aa)
ECSCREndothelial cell-specific chemotaxis regulator isoform X1. (175 aa)
GSK3AGlycogen synthase kinase-3 alpha. (446 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (891 aa)
AMER1APC membrane recruitment protein 1. (1125 aa)
GGA3ADP-ribosylation factor-binding protein GGA3. (729 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (655 aa)
TMTC3Transmembrane and TPR repeat-containing protein 3. (915 aa)
DET1DET1 homolog isoform X4. (512 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
ASB5Ankyrin repeat and SOCS box protein 5. (329 aa)
RNFT2RING finger and transmembrane domain-containing protein 2 isoform X1. (489 aa)
FBXW8F-box/WD repeat-containing protein 8. (577 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
ENSVVUP00000017854annotation not available (106 aa)
OAZ3LOW QUALITY PROTEIN: ornithine decarboxylase antizyme 3. (240 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
AXIN1Axin-1 isoform X1. (880 aa)
COP1E3 ubiquitin-protein ligase COP1. (629 aa)
ENSVVUP00000018409annotation not available (100 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
ENSVVUP00000019211annotation not available (82 aa)
SMAD7Mothers against decapentaplegic homolog. (429 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PIAS1E3 SUMO-protein ligase PIAS1 isoform X1. (655 aa)
MKRN2Probable E3 ubiquitin-protein ligase makorin-2. (416 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1092 aa)
FBXL5F-box/LRR-repeat protein 5. (856 aa)
RNF19BRBR-type E3 ubiquitin transferase. (550 aa)
DDA1DET1- and DDB1-associated protein 1. (101 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
PRICKLE1Prickle-like protein 1. (832 aa)
TRIB1Tribbles homolog 1. (141 aa)
SH3RF1E3 ubiquitin-protein ligase SH3RF1. (882 aa)
SOX17Transcription factor SOX-18. (213 aa)
LDLRLow-density lipoprotein receptor. (866 aa)
RNFT1E3 ubiquitin-protein ligase RNFT1 isoform X1. (397 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
ARIH1RBR-type E3 ubiquitin transferase. (539 aa)
LRP1Prolow-density lipoprotein receptor-related protein 1. (4498 aa)
NKD1Protein naked cuticle homolog 1. (447 aa)
SNX33Sorting nexin. (629 aa)
FBXO22F-box only protein 22. (391 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase. (657 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
SORL1Sortilin-related receptor. (2136 aa)
SH3RF3E3 ubiquitin-protein ligase SH3RF3. (850 aa)
BAG6Large proline-rich protein BAG6 isoform X1. (1167 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
NDFIP1NEDD4 family-interacting protein 1. (247 aa)
SH3RF2E3 ubiquitin-protein ligase SH3RF2. (733 aa)
CDC20BCell division cycle protein 20 homolog B isoform X1. (489 aa)
ENSVVUP00000029378annotation not available (285 aa)
RILPRab-interacting lysosomal protein. (357 aa)
CBLBE3 ubiquitin-protein ligase CBL-B isoform X1. (1019 aa)
RNF41E3 ubiquitin-protein ligase NRDP1. (317 aa)
NKD2Protein naked cuticle homolog 2. (424 aa)
ENSVVUP00000030475annotation not available (321 aa)
LOC112913617Heat shock 70 kDa protein 1; Belongs to the heat shock protein 70 family. (642 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (459 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (549 aa)
MSNMoesin. (577 aa)
TMEM259Membralin. (567 aa)
LOC112908688Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (458 aa)
APC2Adenomatous polyposis coli protein 2. (1719 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (149 aa)
NOP53Ribosome biogenesis protein NOP53 isoform X1. (498 aa)
HERPUD1Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein. (393 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
GGA1ADP-ribosylation factor-binding protein GGA1. (693 aa)
FBXW9F-box/WD repeat-containing protein 9. (461 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (370 aa)
RCHY1RING finger and CHY zinc finger domain-containing protein 1 isoform X1. (259 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons protein 3. (424 aa)
TREM2Triggering receptor expressed on myeloid cells 2 isoform X1. (404 aa)
FOXO1Forkhead box protein O1. (670 aa)
MAPK9Mitogen-activated protein kinase. (382 aa)
CUL4Bcullin-4B isoform X2; Belongs to the cullin family. (948 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (460 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa)
DACT1Dapper homolog 1. (583 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
BCAP31B-cell receptor-associated protein 31. (446 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
STX5Syntaxin-5; Belongs to the syntaxin family. (251 aa)
SEC22BVesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (257 aa)
C4BPBC4b-binding protein beta chain. (255 aa)
ENSVVUP00000034315annotation not available (59 aa)
ENSVVUP00000034799annotation not available (197 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X2. (627 aa)
SH3D19SH3 domain-containing protein 19 isoform X1. (1013 aa)
MARCHF2E3 ubiquitin-protein ligase MARCH2. (246 aa)
DDRGK1DDRGK domain-containing protein 1 isoform X2. (319 aa)
ENSVVUP00000035544annotation not available (382 aa)
DNAJB2dnaJ homolog subfamily B member 2 isoform X1. (355 aa)
RHBDD3Rhomboid domain-containing protein 3. (386 aa)
ZER1Protein zer-1 homolog isoform X1. (768 aa)
ZYG11AProtein zyg-11 homolog A. (755 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
TRIB2Tribbles homolog 2. (435 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (381 aa)
PRKN-2E3 ubiquitin-protein ligase parkin. (176 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (801 aa)
DAB2Disabled homolog 2 isoform X1. (873 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3 isoform X2. (854 aa)
RNF185E3 ubiquitin-protein ligase RNF185. (187 aa)
ZYG11BProtein zyg-11 homolog B. (761 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (853 aa)
OAZ1LOW QUALITY PROTEIN: ornithine decarboxylase antizyme 1. (218 aa)
ENSVVUP00000003415annotation not available (88 aa)
RACK1Receptor of activated protein C kinase 1. (317 aa)
SGTASmall glutamine-rich tetratricopeptide repeat-containing protein alpha. (313 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: medium (72%) [HD]