16 items (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTN4	Alpha-actinin-4 isoform X3. (911 aa)
	CYP26B1	Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (561 aa)
	RXRG	Retinoic acid receptor RXR-gamma. (538 aa)
	ESRRG	Estrogen-related receptor gamma isoform X2. (435 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (475 aa)
	PML	Protein PML. (406 aa)
	CRKL	Crk-like protein. (303 aa)
	RXRB	Retinoic acid receptor RXR-beta. (525 aa)
	RXRA	Retinoic acid receptor RXR-alpha isoform X1. (568 aa)
	RARG	Retinoic acid receptor gamma isoform X1. (648 aa)
	RARB	Retinoic acid receptor beta isoform X2. (448 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (579 aa)
	ENSVVUP00000042332	annotation not available (107 aa)
	RARA	Retinoic acid receptor alpha isoform X2. (500 aa)
	ALDH1A2	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	SNW1	SNW domain-containing protein 1. (536 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	CYP26B1	ENSVVUP00000001570	ENSVVUP00000009626	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 26B1; Belongs to the cytochrome P450 family.	0.942
CYP26B1	ALDH1A2	ENSVVUP00000009626	ENSVVUP00000001570	Cytochrome P450 26B1; Belongs to the cytochrome P450 family.	Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family.	0.942
CYP26B1	RARB	ENSVVUP00000009626	ENSVVUP00000039584	Cytochrome P450 26B1; Belongs to the cytochrome P450 family.	Retinoic acid receptor beta isoform X2.	0.483
CYP26B1	RARG	ENSVVUP00000009626	ENSVVUP00000039400	Cytochrome P450 26B1; Belongs to the cytochrome P450 family.	Retinoic acid receptor gamma isoform X1.	0.406
NR1D2	PPARG	ENSVVUP00000039614	ENSVVUP00000020742	Nuclear receptor subfamily 1 group D member 2.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.625
NR1D2	RARA	ENSVVUP00000039614	ENSVVUP00000001022	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor alpha isoform X2.	0.585
NR1D2	RARB	ENSVVUP00000039614	ENSVVUP00000039584	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor beta isoform X2.	0.585
NR1D2	RARG	ENSVVUP00000039614	ENSVVUP00000039400	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor gamma isoform X1.	0.585
NR1D2	RXRA	ENSVVUP00000039614	ENSVVUP00000038604	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor RXR-alpha isoform X1.	0.453
NR1D2	RXRB	ENSVVUP00000039614	ENSVVUP00000035105	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor RXR-beta.	0.453
NR1D2	RXRG	ENSVVUP00000039614	ENSVVUP00000013817	Nuclear receptor subfamily 1 group D member 2.	Retinoic acid receptor RXR-gamma.	0.453
PML	RARA	ENSVVUP00000025222	ENSVVUP00000001022	Protein PML.	Retinoic acid receptor alpha isoform X2.	0.959
PML	RARB	ENSVVUP00000025222	ENSVVUP00000039584	Protein PML.	Retinoic acid receptor beta isoform X2.	0.418
PML	RARG	ENSVVUP00000025222	ENSVVUP00000039400	Protein PML.	Retinoic acid receptor gamma isoform X1.	0.418
PPARG	NR1D2	ENSVVUP00000020742	ENSVVUP00000039614	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Nuclear receptor subfamily 1 group D member 2.	0.625
PPARG	RXRA	ENSVVUP00000020742	ENSVVUP00000038604	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor RXR-alpha isoform X1.	0.999
PPARG	RXRB	ENSVVUP00000020742	ENSVVUP00000035105	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor RXR-beta.	0.982
PPARG	RXRG	ENSVVUP00000020742	ENSVVUP00000013817	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Retinoic acid receptor RXR-gamma.	0.988
RARA	NR1D2	ENSVVUP00000001022	ENSVVUP00000039614	Retinoic acid receptor alpha isoform X2.	Nuclear receptor subfamily 1 group D member 2.	0.585
RARA	PML	ENSVVUP00000001022	ENSVVUP00000025222	Retinoic acid receptor alpha isoform X2.	Protein PML.	0.959