STRINGSTRING
AUNIP AUNIP LOC112910274 LOC112910274 NBN NBN GNL3L GNL3L PINX1 PINX1 ENSVVUP00000002949 ENSVVUP00000002949 GMNN GMNN TRIM28 TRIM28 CDT1 CDT1 ERCC1 ERCC1 ENSVVUP00000005499 ENSVVUP00000005499 THOC1 THOC1 MSH2 MSH2 MSH6 MSH6 UBQLN4 UBQLN4 CYREN CYREN ZRANB3 ZRANB3 BLM BLM GATA3 GATA3 ENSVVUP00000008883 ENSVVUP00000008883 RAD17 RAD17 FBH1 FBH1 POT1 POT1 FBXO5 FBXO5 SMARCAL1 SMARCAL1 HSF1 HSF1 CERS1 CERS1 SMCHD1 SMCHD1 XRCC1 XRCC1 XRCC5 XRCC5 CDAN1 CDAN1 FANCB FANCB RADX RADX TP53BP1 TP53BP1 NRM NRM NAT10 NAT10 TSPYL2 TSPYL2 RECQL5 RECQL5 ENSVVUP00000015737 ENSVVUP00000015737 HELB HELB HMGA2 HMGA2 MAGEF1 MAGEF1 RIF1 RIF1 NIBAN2 NIBAN2 ACD ACD KLHL15 KLHL15 ADIPOQ ADIPOQ BCL6 BCL6 GMNC GMNC H1-8 H1-8 ENSVVUP00000019506 ENSVVUP00000019506 TIPIN TIPIN PDS5A PDS5A LOC112920814 LOC112920814 ATM ATM ENSVVUP00000021885 ENSVVUP00000021885 SLX4 SLX4 NUDT16L1 NUDT16L1 UBR5 UBR5 TERF2 TERF2 LOC112923220 LOC112923220 ENPP7 ENPP7 ENSVVUP00000024478 ENSVVUP00000024478 PARPBP PARPBP FOXP3 FOXP3 DACH1 DACH1 BMPR2 BMPR2 H1-10 H1-10 ENSVVUP00000025132 ENSVVUP00000025132 CCDC197 CCDC197 OTUB2 OTUB2 TERF1 TERF1 ERCC4 ERCC4 TNKS TNKS LIG3 LIG3 ZNF830 ZNF830 ERCC6 ERCC6 NDFIP1 NDFIP1 GZMA GZMA MCIDAS MCIDAS TIMELESS TIMELESS TNKS2 TNKS2 SMG6 SMG6 ANKRD1 ANKRD1 SUB1 SUB1 POLQ POLQ DONSON DONSON SHLD1 SHLD1 OGG1 OGG1 DNMT3L DNMT3L ATR ATR RPS3 RPS3 RNF169 RNF169 ENSVVUP00000033849 ENSVVUP00000033849 RAD50 RAD50 TERF2IP TERF2IP MSH3 MSH3 ENSVVUP00000035005 ENSVVUP00000035005 LOC112920444 LOC112920444 LOC112920478 LOC112920478 H1-1 H1-1 WAPL WAPL SHLD2 SHLD2 GDF2 GDF2 DCP2 DCP2 CDKN1A CDKN1A BRCA2 BRCA2 HNRNPU HNRNPU PARP3 PARP3 DFFB DFFB DFFA DFFA EXOSC10 EXOSC10 ACVRL1 ACVRL1 TP53 TP53 CTC1 CTC1 MAD2L2 MAD2L2 TINF2 TINF2 SRC SRC OTUB1 OTUB1 FLCN FLCN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AUNIPAurora kinase A and ninein-interacting protein. (416 aa)
LOC112910274Histone H1.4-like. (213 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (792 aa)
GNL3LGuanine nucleotide-binding protein-like 3-like protein. (649 aa)
PINX1PIN2/TERF1-interacting telomerase inhibitor 1. (512 aa)
ENSVVUP00000002949annotation not available (75 aa)
GMNNGeminin. (250 aa)
TRIM28Transcription intermediary factor 1-beta. (789 aa)
CDT1DNA replication factor Cdt1. (512 aa)
ERCC1DNA excision repair protein ERCC-1 isoform X1. (405 aa)
ENSVVUP00000005499annotation not available (170 aa)
THOC1THO complex subunit 1. (657 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (852 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
UBQLN4Ubiquilin-4. (573 aa)
CYRENCell cycle regulator of non-homologous end joining isoform X1. (215 aa)
ZRANB3DNA annealing helicase and endonuclease ZRANB3. (1082 aa)
BLMBloom syndrome protein. (1420 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (444 aa)
ENSVVUP00000008883annotation not available (86 aa)
RAD17Cell cycle checkpoint protein RAD17 isoform X1. (680 aa)
FBH1F-box DNA helicase 1. (1163 aa)
POT1Protection of telomeres protein 1 isoform X1. (731 aa)
FBXO5F-box only protein 5. (448 aa)
SMARCAL1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (961 aa)
HSF1Heat shock factor protein 1 isoform X2. (554 aa)
CERS1Ceramide synthase 1 isoform X1. (310 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain-containing protein 1. (2007 aa)
XRCC1DNA repair protein XRCC1. (629 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (799 aa)
CDAN1Codanin-1. (1207 aa)
FANCBFanconi anemia group B protein. (850 aa)
RADXRPA-related protein RADX isoform X1. (862 aa)
TP53BP1TP53-binding protein 1 isoform X1. (1976 aa)
NRMNurim. (262 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (990 aa)
TSPYL2Testis-specific Y-encoded-like protein 2 isoform X1; Belongs to the nucleosome assembly protein (NAP) family. (725 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (989 aa)
ENSVVUP00000015737annotation not available (217 aa)
HELBDNA helicase B. (744 aa)
HMGA2High mobility group protein HMGI-C. (239 aa)
MAGEF1Melanoma-associated antigen F1. (318 aa)
RIF1Telomere-associated protein RIF1 isoform X1. (2447 aa)
NIBAN2Niban-like protein 1. (771 aa)
ACDAdrenocortical dysplasia protein homolog isoform X2. (400 aa)
KLHL15Kelch-like protein 15. (604 aa)
ADIPOQAdiponectin. (266 aa)
BCL6B-cell lymphoma 6 protein. (721 aa)
GMNCGeminin coiled-coil domain-containing protein 1. (318 aa)
H1-8LOW QUALITY PROTEIN: histone H1oo. (326 aa)
ENSVVUP00000019506annotation not available (131 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (265 aa)
PDS5ASister chromatid cohesion protein PDS5 homolog A isoform X1. (1366 aa)
LOC112920814CST complex subunit TEN1 isoform X5. (121 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3060 aa)
ENSVVUP00000021885annotation not available (135 aa)
SLX4Structure-specific endonuclease subunit SLX4. (1743 aa)
NUDT16L1Tudor-interacting repair regulator protein. (210 aa)
UBR5E3 ubiquitin-protein ligase UBR5. (2748 aa)
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (528 aa)
LOC112923220Ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like. (422 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase family member 7. (433 aa)
ENSVVUP00000024478annotation not available (157 aa)
PARPBPPCNA-interacting partner. (586 aa)
FOXP3Forkhead box protein P3. (430 aa)
DACH1LOW QUALITY PROTEIN: dachshund homolog 1. (661 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
H1-10Histone H1x. (213 aa)
ENSVVUP00000025132annotation not available (150 aa)
CCDC197Uncharacterized protein CCDC197. (311 aa)
OTUB2Ubiquitin thioesterase. (256 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (432 aa)
ERCC4DNA repair endonuclease XPF isoform X1. (916 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
LIG3DNA ligase. (990 aa)
ZNF830Zinc finger protein 830. (373 aa)
ERCC6DNA excision repair protein ERCC-6 isoform X1. (1485 aa)
NDFIP1NEDD4 family-interacting protein 1. (247 aa)
GZMAGranzyme A; Belongs to the peptidase S1 family. (260 aa)
MCIDASMulticilin. (385 aa)
TIMELESSProtein timeless homolog isoform X1. (1248 aa)
TNKS2Poly [ADP-ribose] polymerase. (1317 aa)
SMG6Telomerase-binding protein EST1A isoform X1. (1412 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (339 aa)
SUB1Activated RNA polymerase II transcriptional coactivator p15. (127 aa)
POLQDNA polymerase theta. (2594 aa)
DONSONProtein downstream neighbor of Son. (450 aa)
SHLD1Shieldin complex subunit 1. (278 aa)
OGG1N-glycosylase/DNA lyase isoform X1. (322 aa)
DNMT3LDNA (Cytosine-5)-methyltransferase 3-like. (635 aa)
ATRSerine/threonine-protein kinase ATR isoform X2; Belongs to the PI3/PI4-kinase family. (2637 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
RNF169E3 ubiquitin-protein ligase RNF169. (556 aa)
ENSVVUP00000033849annotation not available (314 aa)
RAD50DNA repair protein RAD50 isoform X1. (1312 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (406 aa)
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1113 aa)
ENSVVUP00000035005annotation not available (119 aa)
LOC112920444Histone H1.4. (215 aa)
LOC112920478Histone H1t. (210 aa)
H1-1Histone H1.1. (215 aa)
WAPLWings apart-like protein homolog isoform X1. (1196 aa)
SHLD2Shieldin complex subunit 2 isoform X1. (918 aa)
GDF2Growth/differentiation factor 2. (417 aa)
DCP2m7GpppN-mRNA hydrolase. (422 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (164 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3446 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X2. (806 aa)
PARP3Poly [ADP-ribose] polymerase. (531 aa)
DFFBDNAation factor subunit beta isoform X4. (341 aa)
DFFADNAation factor subunit alpha. (163 aa)
EXOSC10Exosome component 10. (803 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
CTC1CST complex subunit CTC1 isoform X2. (1299 aa)
MAD2L2Mitotic spindle assembly checkpoint protein MAD2B. (211 aa)
TINF2LOW QUALITY PROTEIN: TERF1-interacting nuclear factor 2. (167 aa)
SRCTyrosine-protein kinase. (536 aa)
OTUB1Ubiquitin thioesterase. (314 aa)
FLCNFolliculin. (935 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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