STRINGSTRING
SIRT7 SIRT7 ENSVVUP00000000439 ENSVVUP00000000439 ENSVVUP00000001376 ENSVVUP00000001376 LOC112914244 LOC112914244 RNLS RNLS IDH3A IDH3A PARP1 PARP1 ENSVVUP00000002743 ENSVVUP00000002743 ALDH1A1 ALDH1A1 SIRT5 SIRT5 ENSVVUP00000004938 ENSVVUP00000004938 ENSVVUP00000005117 ENSVVUP00000005117 AHCY AHCY LOC112928185 LOC112928185 GPD1L GPD1L ENSVVUP00000007165 ENSVVUP00000007165 CTBP2 CTBP2 SIRT2 SIRT2 CRYL1 CRYL1 IDH2 IDH2 LOC112935269 LOC112935269 ADH4 ADH4 SIRT6 SIRT6 ENSVVUP00000011882 ENSVVUP00000011882 B3GAT2 B3GAT2 BDH2 BDH2 NDUFV1 NDUFV1 ENSVVUP00000014184 ENSVVUP00000014184 ENSVVUP00000014749 ENSVVUP00000014749 SORD SORD IDH1 IDH1 ENSVVUP00000016087 ENSVVUP00000016087 ENSVVUP00000016670 ENSVVUP00000016670 LOC112915292 LOC112915292 UXS1 UXS1 EHHADH EHHADH CTBP1 CTBP1 NUDT6 NUDT6 ALDH1A3 ALDH1A3 ENSVVUP00000019648 ENSVVUP00000019648 ME2 ME2 ENSVVUP00000019822 ENSVVUP00000019822 UGDH UGDH SIRT3 SIRT3 GAPDHS GAPDHS QDPR QDPR NDUFS2 NDUFS2 HADHA HADHA GLYR1 GLYR1 HPGD HPGD HADH HADH ENSVVUP00000024346 ENSVVUP00000024346 ENSVVUP00000024402 ENSVVUP00000024402 ENSVVUP00000024578 ENSVVUP00000024578 ME3 ME3 ME1 ME1 SIRT1 SIRT1 GRHPR GRHPR ENSVVUP00000028374 ENSVVUP00000028374 SIRT4 SIRT4 ENSVVUP00000029569 ENSVVUP00000029569 PARP15 PARP15 PARP14 PARP14 GPD1 GPD1 ENSVVUP00000034054 ENSVVUP00000034054 HIBADH HIBADH LOC112922800 LOC112922800 HSD17B8 HSD17B8 LOC112915292-2 LOC112915292-2 ENSVVUP00000035368 ENSVVUP00000035368 IDH3B IDH3B ENSVVUP00000035812 ENSVVUP00000035812 LOC112922830 LOC112922830 LOC112933858 LOC112933858 LOC112919802 LOC112919802 B3GAT1 B3GAT1 ENSVVUP00000040951 ENSVVUP00000040951 IDH3G IDH3G ENSVVUP00000041879 ENSVVUP00000041879 B3GAT3 B3GAT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIRT7NAD-dependent protein deacetylase sirtuin-7. (475 aa)
ENSVVUP00000000439annotation not available (325 aa)
ENSVVUP00000001376annotation not available (397 aa)
LOC112914244Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (291 aa)
RNLSRenalase isoform X1. (300 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (377 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (972 aa)
ENSVVUP00000002743annotation not available (255 aa)
ALDH1A1Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (501 aa)
SIRT5Sirtuin 5. (315 aa)
ENSVVUP00000004938annotation not available (133 aa)
ENSVVUP00000005117annotation not available (85 aa)
AHCYAdenosylhomocysteinase. (421 aa)
LOC112928185NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (266 aa)
GPD1LGlycerol-3-phosphate dehydrogenase [NAD(+)]. (312 aa)
ENSVVUP00000007165annotation not available (289 aa)
CTBP2C-terminal-binding protein 2 isoform X3; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (412 aa)
CRYL1Lambda-crystallin homolog. (319 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
LOC112935269Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
ADH4Alcohol dehydrogenase 4. (379 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform X1. (330 aa)
ENSVVUP00000011882annotation not available (276 aa)
B3GAT2Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (329 aa)
BDH23-hydroxybutyrate dehydrogenase type 2 isoform X1. (255 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
ENSVVUP00000014184annotation not available (326 aa)
ENSVVUP00000014749annotation not available (85 aa)
SORDSorbitol dehydrogenase. (357 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
ENSVVUP00000016087annotation not available (409 aa)
ENSVVUP00000016670annotation not available (219 aa)
LOC112915292Glyceraldehyde-3-phosphate dehydrogenase. (325 aa)
UXS1UDP-glucuronic acid decarboxylase 1 isoform X2. (551 aa)
EHHADHPeroxisomal bifunctional enzyme isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
CTBP1C-terminal-binding protein 1 isoform X1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (422 aa)
NUDT6Nucleoside diphosphate-linked moiety X motif 6 isoform X1; Belongs to the Nudix hydrolase family. (307 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
ENSVVUP00000019648annotation not available (311 aa)
ME2Malic enzyme. (584 aa)
ENSVVUP00000019822annotation not available (256 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (373 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (386 aa)
QDPRDihydropteridine reductase isoform X1. (242 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (816 aa)
HADHATrifunctional enzyme subunit alpha, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (762 aa)
GLYR1Putative oxidoreductase GLYR1 isoform X1. (603 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
HADHHydroxyacyl-coenzyme A dehydrogenase, mitochondrial. (357 aa)
ENSVVUP00000024346annotation not available (235 aa)
ENSVVUP00000024402annotation not available (334 aa)
ENSVVUP00000024578annotation not available (197 aa)
ME3Malic enzyme. (575 aa)
ME1Malic enzyme. (571 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1. (769 aa)
GRHPRGlyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (335 aa)
ENSVVUP00000028374annotation not available (255 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (313 aa)
ENSVVUP00000029569annotation not available (293 aa)
PARP15Poly [ADP-ribose] polymerase. (684 aa)
PARP14Poly [ADP-ribose] polymerase. (1792 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (348 aa)
ENSVVUP00000034054annotation not available (248 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
LOC112922800Aldehyde oxidase 2. (1340 aa)
HSD17B8Estradiol 17-beta-dehydrogenase 8 isoform X5. (294 aa)
LOC112915292-2Glyceraldehyde-3-phosphate dehydrogenase-like. (309 aa)
ENSVVUP00000035368annotation not available (182 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
ENSVVUP00000035812Glyceraldehyde-3-phosphate dehydrogenase-like. (260 aa)
LOC112922830Aldehyde oxidase 4-like. (1373 aa)
LOC112933858Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (305 aa)
LOC112919802Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (398 aa)
B3GAT1Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (437 aa)
ENSVVUP00000040951annotation not available (145 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (450 aa)
ENSVVUP00000041879annotation not available (366 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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