STRINGSTRING
ZFPM1 ZFPM1 NKX2-5 NKX2-5 SAV1 SAV1 BMP4 BMP4 NOTCH1 NOTCH1 BMPR1A BMPR1A HES1 HES1 WNT11 WNT11 NSD2 NSD2 TGFBR1 TGFBR1 BMPR2 BMPR2 FZD2 FZD2 APLNR APLNR ZFPM2 ZFPM2 SMAD4 SMAD4 SMAD7 SMAD7 SLIT2 SLIT2 TBX3 TBX3 NOG NOG PROX1 PROX1 GJA5 GJA5 SLIT3 SLIT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZFPM1Zinc finger protein ZFPM1. (703 aa)
NKX2-5Homeobox protein Nkx-2.5. (322 aa)
SAV1Protein salvador homolog 1. (351 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (409 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2644 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
HES1Transcription factor HES-1. (282 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NSD2LOW QUALITY PROTEIN: histone-lysine N-methyltransferase NSD2. (1344 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
ZFPM2Zinc finger protein ZFPM2. (1103 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD7Mothers against decapentaplegic homolog. (429 aa)
SLIT2Slit homolog 2 protein. (1329 aa)
TBX3T-box transcription factor TBX3 isoform X1. (737 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (216 aa)
PROX1Prospero homeobox protein 1 isoform X2. (737 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
SLIT3Slit homolog 3 protein. (1372 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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