STRINGSTRING
CCN1 CCN1 JUNB JUNB IL10 IL10 GCM1 GCM1 PCDH12 PCDH12 MAPK1 MAPK1 ST14 ST14 GGNBP2 GGNBP2 PLCD3 PLCD3 LEF1 LEF1 SOCS3 SOCS3 SPINT2 SPINT2 FBXW8 FBXW8 BIRC6 BIRC6 GRB2 GRB2 WNT2 WNT2 HS6ST1 HS6ST1 VASH2 VASH2 NSDHL NSDHL SPINT2-2 SPINT2-2 ZFP36L1 ZFP36L1 VASH1 VASH1 GJB5 GJB5 SPINT1 SPINT1 RSPO3 RSPO3 HES1 HES1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCN1Protein CYR61 isoform X1. (520 aa)
JUNBTranscription factor jun-B. (347 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (179 aa)
GCM1Chorion-specific transcription factor GCMa. (455 aa)
PCDH12Protocadherin-12. (1202 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (832 aa)
GGNBP2Gametogenetin-binding protein 2 isoform X2. (738 aa)
PLCD3Phosphoinositide phospholipase C. (713 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X3. (468 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
SPINT2Kunitz-type protease inhibitor 2 isoform X1. (248 aa)
FBXW8F-box/WD repeat-containing protein 8. (577 aa)
BIRC6Baculoviral IAP repeat-containing protein 6 isoform X3. (4983 aa)
GRB2Growth factor receptor-bound protein 2. (351 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (401 aa)
VASH2Vasohibin-2 isoform X1. (355 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X2; Belongs to the 3-beta-HSD family. (361 aa)
SPINT2-2Kunitz-type protease inhibitor 2 isoform X1. (74 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
VASH1Vasohibin-1 isoform X2. (363 aa)
GJB5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (273 aa)
SPINT1Kunitz-type protease inhibitor 1. (595 aa)
RSPO3R-spondin-3 isoform X1. (279 aa)
HES1Transcription factor HES-1. (282 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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