STRINGSTRING
SIRT1 SIRT1 FUNDC2 FUNDC2 PLA2G12B PLA2G12B ANGPTL4 ANGPTL4 APOA4 APOA4 ANGPTL3 ANGPTL3 NR1H3 NR1H3 SCARB1 SCARB1 XBP1 XBP1 NR1H4 NR1H4 MED13 MED13 PNPLA8 PNPLA8 GCKR GCKR APOE APOE APOC2 APOC2 RORA RORA LIPC LIPC HNF4A HNF4A FITM2 FITM2 GPIHBP1 GPIHBP1 ANGPTL8 ANGPTL8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SIRT1NAD-dependent protein deacetylase sirtuin-1. (769 aa)
FUNDC2FUN14 domain-containing protein 2. (172 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
ANGPTL4Angiopoietin-related protein 4. (464 aa)
APOA4Apolipoprotein A-IV. (388 aa)
ANGPTL3Angiopoietin-related protein 3. (459 aa)
NR1H3Oxysterols receptor LXR-alpha. (447 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (486 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (227 aa)
NR1H4Bile acid receptor isoform X2. (481 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2042 aa)
PNPLA8Calcium-independent phospholipase A2-gamma. (784 aa)
GCKRGlucokinase regulatory protein isoform X2. (600 aa)
APOEApolipoprotein E. (336 aa)
APOC2Apolipoprotein C-II isoform X1. (101 aa)
RORANuclear receptor ROR-alpha. (473 aa)
LIPCHepatic triacylglycerol lipase. (501 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X2. (474 aa)
FITM2Fat storage-inducing transmembrane protein 2. (262 aa)
GPIHBP1Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1. (275 aa)
ANGPTL8Angiopoietin-like protein 8. (198 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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