STRINGSTRING
SSB SSB MTPAP MTPAP UPF1 UPF1 EXOSC4 EXOSC4 ENSVVUP00000020147 ENSVVUP00000020147 ATM ATM LSM1 LSM1 TENT2 TENT2 DCP2 DCP2 XRN1 XRN1 EXOSC10 EXOSC10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SSBLupus La protein. (523 aa)
MTPAPpoly(A) RNA polymerase, mitochondrial. (584 aa)
UPF1Regulator of nonsense transcripts 1 isoform X2. (1119 aa)
EXOSC4Exosome complex component RRP41. (245 aa)
ENSVVUP00000020147annotation not available (94 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3060 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
TENT2poly(A) RNA polymerase GLD2 isoform X2. (480 aa)
DCP2m7GpppN-mRNA hydrolase. (422 aa)
XRN15'-3' exoribonuclease 1 isoform X2. (1731 aa)
EXOSC10Exosome component 10. (803 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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