(20 nodes) Cellular response to cadmium ion network (Vulpes vulpes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	LOC112927216	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	HSF1	Heat shock factor protein 1 isoform X2. (554 aa)
	ENSVVUP00000013279	annotation not available (61 aa)
	EGFR	Receptor protein-tyrosine kinase. (1154 aa)
	ENSVVUP00000017517	annotation not available (118 aa)
	ENSVVUP00000018872	annotation not available (61 aa)
	NCF1	Neutrophil cytosol factor 1. (365 aa)
	ENSVVUP00000024290	annotation not available (257 aa)
	MAPK1	Mitogen-activated protein kinase. (392 aa)
	HESX1	Homeobox expressed in ES cells 1. (189 aa)
	MT3	Metallothionein 3. (68 aa)
	LOC112929582	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (64 aa)
	LOC112929633	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (61 aa)
	CER1	Cerberus. (270 aa)
	HMOX1	Heme oxygenase 1. (377 aa)
	CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (745 aa)
	DAXX	Death domain-associated protein 6 isoform X2. (733 aa)
	ABCB6	ATP-binding cassette sub-family B member 6, mitochondrial. (979 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	MAPK9	Mitogen-activated protein kinase. (382 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSVVUP00000013279	MT3	ENSVVUP00000013279	ENSVVUP00000029817	annotation not available	Metallothionein 3.	0.608
ENSVVUP00000017517	HSF1	ENSVVUP00000017517	ENSVVUP00000010454	annotation not available	Heat shock factor protein 1 isoform X2.	0.779
ENSVVUP00000024290	HSF1	ENSVVUP00000024290	ENSVVUP00000010454	annotation not available	Heat shock factor protein 1 isoform X2.	0.779
ENSVVUP00000024290	MAPK1	ENSVVUP00000024290	ENSVVUP00000027843	annotation not available	Mitogen-activated protein kinase.	0.766
HMOX1	NCF1	ENSVVUP00000032454	ENSVVUP00000020297	Heme oxygenase 1.	Neutrophil cytosol factor 1.	0.454
HSF1	ENSVVUP00000017517	ENSVVUP00000010454	ENSVVUP00000017517	Heat shock factor protein 1 isoform X2.	annotation not available	0.779
HSF1	ENSVVUP00000024290	ENSVVUP00000010454	ENSVVUP00000024290	Heat shock factor protein 1 isoform X2.	annotation not available	0.779
HSF1	MAPK1	ENSVVUP00000010454	ENSVVUP00000027843	Heat shock factor protein 1 isoform X2.	Mitogen-activated protein kinase.	0.890
HSF1	MAPK3	ENSVVUP00000010454	ENSVVUP00000036212	Heat shock factor protein 1 isoform X2.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.779
LOC112927216	LOC112929582	ENSVVUP00000004809	ENSVVUP00000029818	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.910
LOC112927216	LOC112929633	ENSVVUP00000004809	ENSVVUP00000029821	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.901
LOC112929582	LOC112927216	ENSVVUP00000029818	ENSVVUP00000004809	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.910
LOC112929582	LOC112929633	ENSVVUP00000029818	ENSVVUP00000029821	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.910
LOC112929582	MT3	ENSVVUP00000029818	ENSVVUP00000029817	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein 3.	0.537
LOC112929633	LOC112927216	ENSVVUP00000029821	ENSVVUP00000004809	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.901
LOC112929633	LOC112929582	ENSVVUP00000029821	ENSVVUP00000029818	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.910
MAPK1	ENSVVUP00000024290	ENSVVUP00000027843	ENSVVUP00000024290	Mitogen-activated protein kinase.	annotation not available	0.766
MAPK1	HSF1	ENSVVUP00000027843	ENSVVUP00000010454	Mitogen-activated protein kinase.	Heat shock factor protein 1 isoform X2.	0.890
MAPK1	MAPK3	ENSVVUP00000027843	ENSVVUP00000036212	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.975
MAPK1	NCF1	ENSVVUP00000027843	ENSVVUP00000020297	Mitogen-activated protein kinase.	Neutrophil cytosol factor 1.	0.933