(15 nodes) Cellular response to dsRNA network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RIOK3	Serine/threonine-protein kinase RIO3. (685 aa)
	COLEC12	Collectin-12. (768 aa)
	DHX9	ATP-dependent RNA helicase A isoform X1. (1276 aa)
	STING1	Stimulator of interferon genes protein isoform X1. (375 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (431 aa)
	LOC112912456	Interferon-induced protein with tetratricopeptide repeats 1-like. (480 aa)
	LOC112912454	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like. (451 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
	PQBP1	Polyglutamine-binding protein 1 isoform X1. (357 aa)
	RALB	Ras-related protein Ral-B. (206 aa)
	IFIH1	Interferon-induced helicase C domain-containing protein 1. (1027 aa)
	PDE12	2',5'-phosphodiesterase 12. (625 aa)
	DDX58	Probable ATP-dependent RNA helicase DDX58. (875 aa)
	MUL1	Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	FLOT1	ENSVVUP00000014366	ENSVVUP00000014519	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.770
DDX58	IFIH1	ENSVVUP00000028923	ENSVVUP00000025324	Probable ATP-dependent RNA helicase DDX58.	Interferon-induced helicase C domain-containing protein 1.	0.869
DDX58	LOC112912454	ENSVVUP00000028923	ENSVVUP00000014936	Probable ATP-dependent RNA helicase DDX58.	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	0.773
DDX58	LOC112912456	ENSVVUP00000028923	ENSVVUP00000014846	Probable ATP-dependent RNA helicase DDX58.	Interferon-induced protein with tetratricopeptide repeats 1-like.	0.773
DDX58	STING1	ENSVVUP00000028923	ENSVVUP00000013638	Probable ATP-dependent RNA helicase DDX58.	Stimulator of interferon genes protein isoform X1.	0.462
DHX9	PQBP1	ENSVVUP00000012072	ENSVVUP00000024253	ATP-dependent RNA helicase A isoform X1.	Polyglutamine-binding protein 1 isoform X1.	0.912
FLOT1	CAV1	ENSVVUP00000014519	ENSVVUP00000014366	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.770
IFIH1	DDX58	ENSVVUP00000025324	ENSVVUP00000028923	Interferon-induced helicase C domain-containing protein 1.	Probable ATP-dependent RNA helicase DDX58.	0.869
IFIH1	LOC112912454	ENSVVUP00000025324	ENSVVUP00000014936	Interferon-induced helicase C domain-containing protein 1.	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	0.712
IFIH1	LOC112912456	ENSVVUP00000025324	ENSVVUP00000014846	Interferon-induced helicase C domain-containing protein 1.	Interferon-induced protein with tetratricopeptide repeats 1-like.	0.712
IFIH1	STING1	ENSVVUP00000025324	ENSVVUP00000013638	Interferon-induced helicase C domain-containing protein 1.	Stimulator of interferon genes protein isoform X1.	0.511
LOC112912454	DDX58	ENSVVUP00000014936	ENSVVUP00000028923	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	Probable ATP-dependent RNA helicase DDX58.	0.773
LOC112912454	IFIH1	ENSVVUP00000014936	ENSVVUP00000025324	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	Interferon-induced helicase C domain-containing protein 1.	0.712
LOC112912454	LOC112912456	ENSVVUP00000014936	ENSVVUP00000014846	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	Interferon-induced protein with tetratricopeptide repeats 1-like.	0.901
LOC112912456	DDX58	ENSVVUP00000014846	ENSVVUP00000028923	Interferon-induced protein with tetratricopeptide repeats 1-like.	Probable ATP-dependent RNA helicase DDX58.	0.773
LOC112912456	IFIH1	ENSVVUP00000014846	ENSVVUP00000025324	Interferon-induced protein with tetratricopeptide repeats 1-like.	Interferon-induced helicase C domain-containing protein 1.	0.712
LOC112912456	LOC112912454	ENSVVUP00000014846	ENSVVUP00000014936	Interferon-induced protein with tetratricopeptide repeats 1-like.	LOW QUALITY PROTEIN: interferon-induced protein with tetratricopeptide repeats 1B-like.	0.901
PQBP1	DHX9	ENSVVUP00000024253	ENSVVUP00000012072	Polyglutamine-binding protein 1 isoform X1.	ATP-dependent RNA helicase A isoform X1.	0.912
STING1	DDX58	ENSVVUP00000013638	ENSVVUP00000028923	Stimulator of interferon genes protein isoform X1.	Probable ATP-dependent RNA helicase DDX58.	0.462
STING1	IFIH1	ENSVVUP00000013638	ENSVVUP00000025324	Stimulator of interferon genes protein isoform X1.	Interferon-induced helicase C domain-containing protein 1.	0.511