(15 nodes) Metanephric epithelium development network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PKD1	Polycystin-1. (3467 aa)
	SOX9	LOW QUALITY PROTEIN: transcription factor SOX-9. (445 aa)
	SOX8	Transcription factor SOX-8. (480 aa)
	NPHS2	Podocin. (268 aa)
	OSR1	LOW QUALITY PROTEIN: protein odd-skipped-related 1. (294 aa)
	WT1	Wilms tumor protein isoform X2. (514 aa)
	AQP1	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (283 aa)
	HES1	Transcription factor HES-1. (282 aa)
	HES5	Transcription factor HES-5. (139 aa)
	PAX8	Paired box protein Pax-8 isoform X3. (459 aa)
	LAMB2	Laminin subunit beta-2 isoform X2. (1850 aa)
	CALB1	Calbindin. (314 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	LGR4	Leucine-rich repeat-containing G-protein coupled receptor 4. (955 aa)
	PKD2	Polycystin-2. (869 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQP1	NPHS2	ENSVVUP00000029059	ENSVVUP00000016993	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Podocin.	0.441
CALB1	SOX9	ENSVVUP00000002838	ENSVVUP00000013114	Calbindin.	LOW QUALITY PROTEIN: transcription factor SOX-9.	0.468
HES1	HES5	ENSVVUP00000035089	ENSVVUP00000038070	Transcription factor HES-1.	Transcription factor HES-5.	0.910
HES5	HES1	ENSVVUP00000038070	ENSVVUP00000035089	Transcription factor HES-5.	Transcription factor HES-1.	0.910
NPHS2	AQP1	ENSVVUP00000016993	ENSVVUP00000029059	Podocin.	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.441
NPHS2	PAX8	ENSVVUP00000016993	ENSVVUP00000040193	Podocin.	Paired box protein Pax-8 isoform X3.	0.519
NPHS2	WT1	ENSVVUP00000016993	ENSVVUP00000022294	Podocin.	Wilms tumor protein isoform X2.	0.926
PAX8	NPHS2	ENSVVUP00000040193	ENSVVUP00000016993	Paired box protein Pax-8 isoform X3.	Podocin.	0.519
PAX8	WNT9B	ENSVVUP00000040193	ENSVVUP00000006614	Paired box protein Pax-8 isoform X3.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.608
PAX8	WT1	ENSVVUP00000040193	ENSVVUP00000022294	Paired box protein Pax-8 isoform X3.	Wilms tumor protein isoform X2.	0.523
PKD1	PKD2	ENSVVUP00000012886	ENSVVUP00000012477	Polycystin-1.	Polycystin-2.	0.996
PKD2	PKD1	ENSVVUP00000012477	ENSVVUP00000012886	Polycystin-2.	Polycystin-1.	0.996
SOX8	WT1	ENSVVUP00000015507	ENSVVUP00000022294	Transcription factor SOX-8.	Wilms tumor protein isoform X2.	0.437
SOX9	CALB1	ENSVVUP00000013114	ENSVVUP00000002838	LOW QUALITY PROTEIN: transcription factor SOX-9.	Calbindin.	0.468
SOX9	WT1	ENSVVUP00000013114	ENSVVUP00000022294	LOW QUALITY PROTEIN: transcription factor SOX-9.	Wilms tumor protein isoform X2.	0.722
WNT9B	PAX8	ENSVVUP00000006614	ENSVVUP00000040193	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Paired box protein Pax-8 isoform X3.	0.608
WNT9B	WT1	ENSVVUP00000006614	ENSVVUP00000022294	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Wilms tumor protein isoform X2.	0.511
WT1	NPHS2	ENSVVUP00000022294	ENSVVUP00000016993	Wilms tumor protein isoform X2.	Podocin.	0.926
WT1	PAX8	ENSVVUP00000022294	ENSVVUP00000040193	Wilms tumor protein isoform X2.	Paired box protein Pax-8 isoform X3.	0.523
WT1	SOX8	ENSVVUP00000022294	ENSVVUP00000015507	Wilms tumor protein isoform X2.	Transcription factor SOX-8.	0.437