STRINGSTRING
USP8 USP8 LGR4 LGR4 RSPO3 RSPO3 RNF146 RNF146 TBL1XR1 TBL1XR1 BAMBI BAMBI SOX4 SOX4 PIN1 PIN1 TMEM9 TMEM9 PPM1N PPM1N KANK1 KANK1 CCAR2 CCAR2 PPM1B PPM1B CSNK1D CSNK1D FAM53B FAM53B GPC5 GPC5 CAPRIN2 CAPRIN2 EDA EDA FGF9 FGF9 RNF220 RNF220 ENSVVUP00000010695 ENSVVUP00000010695 WLS WLS LGR5 LGR5 EGFR EGFR CAV1 CAV1 YAP1 YAP1 LYPD6 LYPD6 AMER1 AMER1 DDX3X DDX3X USP34 USP34 CDH3 CDH3 FGF2 FGF2 CSNK1G1 CSNK1G1 GPC3 GPC3 JRK JRK LRRK1 LRRK1 GID8 GID8 DLX5 DLX5 LRRK2 LRRK2 PRDM15 PRDM15 UBR5 UBR5 SULF2 SULF2 TTC21B TTC21B SFRP4 SFRP4 DKK2 DKK2 RUVBL1 RUVBL1 TBL1X TBL1X WNT10B WNT10B TNKS TNKS RECK RECK ADGRA2 ADGRA2 SFRP1 SFRP1 NLE1 NLE1 TNKS2 TNKS2 HHEX HHEX LOC112922409 LOC112922409 LOC112908688 LOC112908688 TRPM4 TRPM4 PLEKHA4 PLEKHA4 RSPO1 RSPO1 ILK ILK FZD9 FZD9 SFRP2 SFRP2 USP47 USP47 FGF10 FGF10 TMEM198 TMEM198 PPM1M PPM1M CTDNEP1 CTDNEP1 GSKIP GSKIP PTK7 PTK7 ANKRD39 ANKRD39 XIAP XIAP SRC SRC NRARP NRARP PPM1A PPM1A DACT1 DACT1 DDX3Y DDX3Y
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP8Ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (955 aa)
RSPO3R-spondin-3 isoform X1. (279 aa)
RNF146E3 ubiquitin-protein ligase RNF146. (359 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (573 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
SOX4Transcription factor SOX-4. (170 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (165 aa)
TMEM9Transmembrane protein 9. (205 aa)
PPM1NProbable protein phosphatase 1N. (412 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1347 aa)
CCAR2Cell cycle and apoptosis regulator protein 2 isoform X1. (918 aa)
PPM1BProtein phosphatase 1B isoform X1. (479 aa)
CSNK1DCasein kinase I isoform X1. (412 aa)
FAM53BProtein FAM53B. (426 aa)
GPC5Glypican-5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (326 aa)
CAPRIN2Caprin-2 isoform X2. (1256 aa)
EDAectodysplasin-A; Belongs to the tumor necrosis factor family. (259 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RNF220E3 ubiquitin-protein ligase RNF220 isoform X1. (358 aa)
ENSVVUP00000010695annotation not available (273 aa)
WLSProtein wntless homolog. (529 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5. (296 aa)
EGFRReceptor protein-tyrosine kinase. (1154 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
LYPD6ly6/PLAUR domain-containing protein 6. (182 aa)
AMER1APC membrane recruitment protein 1. (1125 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
USP34LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 34; Belongs to the peptidase C19 family. (3524 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (988 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CSNK1G1Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (516 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
JRKJerky protein homolog. (541 aa)
LRRK1Leucine-rich repeat serine/threonine-protein kinase 1. (2014 aa)
GID8Glucose-induced degradation protein 8 homolog. (229 aa)
DLX5Homeobox protein DLX-5. (289 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X1. (2527 aa)
PRDM15PR domain zinc finger protein 15. (1227 aa)
UBR5E3 ubiquitin-protein ligase UBR5. (2748 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
TTC21BTetratricopeptide repeat protein 21B. (1316 aa)
SFRP4Secreted frizzled-related protein 4. (316 aa)
DKK2Dickkopf-related protein 2. (259 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
TBL1XF-box-like/WD repeat-containing protein TBL1X isoform X2. (526 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs isoform X3. (942 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1393 aa)
SFRP1Secreted frizzled-related protein 1. (293 aa)
NLE1Notchless protein homolog 1. (470 aa)
TNKS2Poly [ADP-ribose] polymerase. (1317 aa)
HHEXHematopoietically expressed homeobox. (228 aa)
LOC112922409Transmembrane protein 198-like isoform X2. (350 aa)
LOC112908688Casein kinase I isoform X1; Belongs to the protein kinase superfamily. (458 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1304 aa)
PLEKHA4Pleckstrin homology domain-containing family A member 4 isoform X2. (780 aa)
RSPO1R-spondin-1. (265 aa)
ILKIntegrin-linked protein kinase. (508 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (558 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
USP47Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1349 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
TMEM198Transmembrane protein 198 isoform X2. (360 aa)
PPM1MProtein phosphatase 1M isoform X1. (458 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (226 aa)
GSKIPGSK3B-interacting protein. (151 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
ANKRD39Ankyrin repeat domain-containing protein 39. (183 aa)
XIAPE3 ubiquitin-protein ligase XIAP. (493 aa)
SRCTyrosine-protein kinase. (536 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
PPM1AProtein phosphatase 1A isoform X1. (518 aa)
DACT1Dapper homolog 1. (583 aa)
DDX3YATP-dependent RNA helicase DDX3X-like isoform X1; Belongs to the DEAD box helicase family. (627 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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