STRINGSTRING
PLCE1 PLCE1 CDC42 CDC42 MYO10 MYO10 ODF2L ODF2L RAP1GAP RAP1GAP ARF6 ARF6 CAPZB CAPZB RCC2 RCC2 ANLN ANLN CROCC CROCC EPHA2 EPHA2 SYNE2 SYNE2 SRF SRF ZMYND10 ZMYND10 EVL EVL MTOR MTOR ABITRAM ABITRAM NDEL1 NDEL1 CNTROB CNTROB FXR2 FXR2 MPHOSPH9 MPHOSPH9 CDC42EP2 CDC42EP2 MSTN MSTN ENTR1 ENTR1 ATMIN ATMIN WRAP73 WRAP73 EVI5L EVI5L TWF2 TWF2 C15orf62 C15orf62 TACSTD2 TACSTD2 SDCCAG8 SDCCAG8 RHOG RHOG F2RL1 F2RL1 HTT HTT ARAP1 ARAP1 TESK1 TESK1 RABEP2 RABEP2 TRPM2 TRPM2 PRKCD PRKCD CDC42EP1 CDC42EP1 CCDC151 CCDC151 RAC2 RAC2 BRK1 BRK1 PPP1R35 PPP1R35 PALM PALM MAPK15 MAPK15 GAP43 GAP43 ATG3 ATG3 CEP97 CEP97 FNBP1L FNBP1L MCIDAS MCIDAS FUZ FUZ ENSVVUP00000029080 ENSVVUP00000029080 DPYSL3 DPYSL3 KIF24 KIF24 CCL19 CCL19 CCL21 CCL21 CCP110 CCP110 WNT1 WNT1 TGFBR1 TGFBR1 CYLD CYLD CEP120 CEP120 CDC42EP3 CDC42EP3 LOC112916471 LOC112916471 ENSVVUP00000025272 ENSVVUP00000025272 BBS4 BBS4 WAS WAS EPS8L2 EPS8L2 TWF1 TWF1 NCKAP1 NCKAP1 P2RX7 P2RX7 MYO3B MYO3B AUTS2 AUTS2 IFT20 IFT20 ENSVVUP00000021432 ENSVVUP00000021432 ODF2 ODF2 TAPT1 TAPT1 SEPTIN9 SEPTIN9 ENSVVUP00000019958 ENSVVUP00000019958 CDKL5 CDKL5 ENSVVUP00000019188 ENSVVUP00000019188 ARHGAP24 ARHGAP24 SLIT2 SLIT2 FAM98C FAM98C PODXL PODXL GPM6A GPM6A LOC112912653 LOC112912653 APC APC WDPCP WDPCP WASF2 WASF2 FAM98A FAM98A TBC1D30 TBC1D30 PFN2 PFN2 CLRN1 CLRN1 IFT140 IFT140 YAP1 YAP1 CAV1 CAV1 MYO3A MYO3A COBL COBL CCDC88A CCDC88A CDC42EP4 CDC42EP4 SH3YL1 SH3YL1 CORO1C CORO1C MARK4 MARK4 CDC42EP5 CDC42EP5 EPS8L1 EPS8L1 ACTR3B ACTR3B DMTN DMTN GDI2 GDI2 OCLN OCLN FXR1 FXR1 DZIP1 DZIP1 PIK3R1 PIK3R1 IFT88 IFT88 FSCN1 FSCN1 CENPJ CENPJ ACTR3 ACTR3 CEP135 CEP135 STAP1 STAP1 RALA RALA RHOQ RHOQ ENSVVUP00000007132 ENSVVUP00000007132 BIN3 BIN3 SAXO2 SAXO2 DEF8 DEF8 LOC112911814 LOC112911814 PIK3CA PIK3CA NEURL1 NEURL1 KANK1 KANK1 ATG5 ATG5 MAK MAK ENSVVUP00000004995 ENSVVUP00000004995 CDK10 CDK10 TBC1D7 TBC1D7 ABI3 ABI3 LOC112907617 LOC112907617 CYFIP1 CYFIP1 EPS8 EPS8 EPS8L3 EPS8L3 RIPOR2 RIPOR2 LIMK2 LIMK2 RAB17 RAB17 PLEKHM1-2 PLEKHM1-2 PLEKHM1 PLEKHM1 NRP1 NRP1 MIEN1 MIEN1 DYNC2LI1 DYNC2LI1 FMR1 FMR1 PLEK2 PLEK2 VDAC3 VDAC3 SAXO1 SAXO1 RAB5A RAB5A ARHGAP35 ARHGAP35
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCE1Phosphoinositide phospholipase C. (2308 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
MYO10Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2030 aa)
ODF2LProtein BCAP isoform X2. (661 aa)
RAP1GAPRap1 GTPase-activating protein 1 isoform X2. (717 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (165 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
RCC2Protein RCC2. (519 aa)
ANLNAnillin. (1117 aa)
CROCCRootletin. (1972 aa)
EPHA2Ephrin type-A receptor 2. (921 aa)
SYNE2Nesprin-2 isoform X2. (6932 aa)
SRFSerum response factor isoform X1. (508 aa)
ZMYND10Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins. Belongs to the ZMYND10 family. (440 aa)
EVLena/VASP-like protein isoform X1. (444 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2553 aa)
ABITRAMProtein Simiate isoform X2. (192 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
CNTROBCentrobin isoform X3. (886 aa)
FXR2Fragile X mental retardation syndrome-related protein 2. (908 aa)
MPHOSPH9M-phase phosphoprotein 9 isoform X2. (1137 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa)
MSTNGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa)
ENTR1Serologically defined colon cancer antigen 3 isoform X1. (435 aa)
ATMINATM interactor. (668 aa)
WRAP73WD repeat-containing protein WRAP73. (491 aa)
EVI5LEVI5-like protein isoform X1. (874 aa)
TWF2Twinfilin-2 isoform X1. (349 aa)
C15orf62Uncharacterized protein C15orf62 homolog, mitochondrial. (177 aa)
TACSTD2Tumor-associated calcium signal transducer 2. (298 aa)
SDCCAG8Serologically defined colon cancer antigen 8 isoform X1. (780 aa)
RHOGRho-related GTP-binding protein RhoG. (191 aa)
F2RL1Proteinase-activated receptor 2. (394 aa)
HTTHuntingtin. (3108 aa)
ARAP1arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 isoform X3. (1202 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
RABEP2Rab GTPase-binding effector protein 2. (515 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2 isoform X1. (1206 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
CDC42EP1LOW QUALITY PROTEIN: cdc42 effector protein 1. (362 aa)
CCDC151Coiled-coil domain-containing protein 151. (650 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (173 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
PPP1R35Protein phosphatase 1 regulatory subunit 35. (267 aa)
PALMParalemmin-1. (291 aa)
MAPK15Mitogen-activated protein kinase. (601 aa)
GAP43Neuromodulin isoform X4. (251 aa)
ATG3Autophagy-related protein 3. (314 aa)
CEP97Centrosomal protein of 97 kDa isoform X1. (945 aa)
FNBP1LFormin-binding protein 1-like. (617 aa)
MCIDASMulticilin. (385 aa)
FUZProtein fuzzy homolog isoform X1. (419 aa)
ENSVVUP00000029080annotation not available (420 aa)
DPYSL3Dihydropyrimidinase-related protein 3. (628 aa)
KIF24Kinesin-like protein KIF24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1365 aa)
CCL19C-C motif chemokine. (272 aa)
CCL21C-C motif chemokine 21. (137 aa)
CCP110Centriolar coiled-coil protein of 110 kDa isoform X1. (1013 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (340 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (490 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform X2; Belongs to the peptidase C19 family. (972 aa)
CEP120Centrosomal protein of 120 kDa isoform X1. (1109 aa)
CDC42EP3Cdc42 effector protein 3. (256 aa)
LOC112916471Probable protein BRICK1. (75 aa)
ENSVVUP00000025272annotation not available (56 aa)
BBS4Bardet-Biedl syndrome 4 protein isoform X1. (520 aa)
WASLOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein. (481 aa)
EPS8L2Epidermal growth factor receptor kinase substrate 8-like protein 2 isoform X1. (713 aa)
TWF1Twinfilin-1. (349 aa)
NCKAP1Nck-associated protein 1 isoform X3. (1150 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
MYO3Bmyosin-IIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1301 aa)
AUTS2Autism susceptibility gene 2 protein isoform X1. (1086 aa)
IFT20Intraflagellar transport protein 20 homolog. (132 aa)
ENSVVUP00000021432LOW QUALITY PROTEIN: akirin-1-like. (136 aa)
ODF2Outer dense fiber protein 2 isoform X4. (829 aa)
TAPT1Transmembrane anterior posterior transformation protein 1 homolog. (511 aa)
SEPTIN9Septin-9 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (578 aa)
ENSVVUP00000019958annotation not available (191 aa)
CDKL5Cyclin-dependent kinase-like 5. (933 aa)
ENSVVUP00000019188annotation not available (143 aa)
ARHGAP24Rho GTPase-activating protein 24 isoform X1. (700 aa)
SLIT2Slit homolog 2 protein. (1329 aa)
FAM98CProtein FAM98C. (143 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (590 aa)
GPM6ANeuronal membrane glycoprotein M6-a. (278 aa)
LOC112912653LOW QUALITY PROTEIN: pleckstrin homology domain-containing family M member 1-like. (92 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog isoform X1. (724 aa)
WASF2wiskott-Aldrich syndrome protein family member 2. (498 aa)
FAM98AProtein FAM98A. (517 aa)
TBC1D30TBC1 domain family member 30 isoform X2. (873 aa)
PFN2Profilin; Belongs to the profilin family. (142 aa)
CLRN1Clarin-1. (232 aa)
IFT140Intraflagellar transport protein 140 homolog. (1459 aa)
YAP1Transcriptional coactivator YAP1. (431 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
MYO3Amyosin-IIIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1614 aa)
COBLProtein cordon-bleu isoform X3. (1287 aa)
CCDC88AGirdin isoform X1. (1873 aa)
CDC42EP4Cdc42 effector protein 4. (604 aa)
SH3YL1SH3 domain-containing YSC84-like protein 1. (273 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
MARK4Non-specific serine/threonine protein kinase. (768 aa)
CDC42EP5Cdc42 effector protein 5. (149 aa)
EPS8L1Epidermal growth factor receptor kinase substrate 8-like protein 1. (690 aa)
ACTR3BActin-related protein 3B isoform X2; Belongs to the actin family. (436 aa)
DMTNDematin. (406 aa)
GDI2Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (423 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (560 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X4. (648 aa)
DZIP1Zinc finger protein DZIP1 isoform X1. (823 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (725 aa)
IFT88Intraflagellar transport protein 88 homolog isoform X1. (825 aa)
FSCN1Fascin. (493 aa)
CENPJCentromere protein J isoform X1. (1355 aa)
ACTR3Actin-related protein 3; Belongs to the actin family. (418 aa)
CEP135Centrosomal protein of 135 kDa isoform X1. (1140 aa)
STAP1Signal-transducing adaptor protein 1. (319 aa)
RALARas-related protein Ral-A. (206 aa)
RHOQRho-related GTP-binding protein RhoQ. (205 aa)
ENSVVUP00000007132annotation not available (147 aa)
BIN3Bridging integrator 3 isoform X1. (322 aa)
SAXO2Stabilizer of axonemal microtubules 2. (398 aa)
DEF8Differentially expressed in FDCP 8 homolog isoform X1. (472 aa)
LOC112911814LOW QUALITY PROTEIN: akirin-1-like. (193 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1. (573 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1347 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MAKSerine/threonine-protein kinase MAK. (648 aa)
ENSVVUP00000004995annotation not available (128 aa)
CDK10Cyclin-dependent kinase 10 isoform X3; Belongs to the protein kinase superfamily. (422 aa)
TBC1D7TBC1 domain family member 7 isoform X1. (293 aa)
ABI3ABI gene family member 3. (218 aa)
LOC112907617Rho-related GTP-binding protein RhoG-like. (226 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1270 aa)
EPS8Epidermal growth factor receptor kinase substrate 8 isoform X1. (861 aa)
EPS8L3Epidermal growth factor receptor kinase substrate 8-like protein 3. (727 aa)
RIPOR2Rho family-interacting cell polarization regulator 2 isoform X2. (1206 aa)
LIMK2LIM domain kinase 2 isoform X2. (617 aa)
RAB17Ras-related protein Rab-17. (353 aa)
PLEKHM1-2Pleckstrin homology domain-containing family M member 1 isoform X1. (310 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (142 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
MIEN1Migration and invasion enhancer 1. (115 aa)
DYNC2LI1Cytoplasmic dynein 2 light intermediate chain 1 isoform X1. (348 aa)
FMR1Synaptic functional regulator FMR1 isoform X1. (599 aa)
PLEK2Pleckstrin-2. (353 aa)
VDAC3Voltage-dependent anion-selective channel protein 3 isoform X2. (283 aa)
SAXO1Stabilizer of axonemal microtubules 1. (505 aa)
RAB5ARas-related protein Rab-5A. (215 aa)
ARHGAP35Rho GTPase-activating protein 35. (1516 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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