STRINGSTRING
PKHD1 PKHD1 ARHGEF10 ARHGEF10 FLNA FLNA MECP2 MECP2 DLGAP5 DLGAP5 KHDC3L-2 KHDC3L-2 SMC1A SMC1A EFHC1 EFHC1 TOGARAM1 TOGARAM1 GPSM2 GPSM2 ITGB1 ITGB1 RMDN1 RMDN1 SAPCD2 SAPCD2 AURKC AURKC FBXW11 FBXW11 CCDC61 CCDC61 SPDL1 SPDL1 TOGARAM2 TOGARAM2 KPNB1 KPNB1 SETD2 SETD2 ENSVVUP00000004945 ENSVVUP00000004945 DCTN1 DCTN1 KIF2A KIF2A KIF3B KIF3B LOC112911081 LOC112911081 MAPRE1-2 MAPRE1-2 KIFC2 KIFC2 BCCIP BCCIP PLK1 PLK1 ABRAXAS2 ABRAXAS2 MZT1 MZT1 PRC1 PRC1 STIL STIL CENPH CENPH ENSVVUP00000009373 ENSVVUP00000009373 KIF4A KIF4A NDC80 NDC80 MAP10 MAP10 SMC3 SMC3 KIF27 KIF27 NSFL1C NSFL1C TPX2 TPX2 SPAST SPAST TBCE TBCE CENPE CENPE NEK2 NEK2 NUF2 NUF2 MAP1S MAP1S CEP126 CEP126 ENSVVUP00000015176 ENSVVUP00000015176 MAPRE1 MAPRE1 TACC2 TACC2 ANKFN1 ANKFN1 CDK5RAP2 CDK5RAP2 EFHC2 EFHC2 ENSVVUP00000016274 ENSVVUP00000016274 NUDC NUDC RCC1 RCC1 ENSVVUP00000017237 ENSVVUP00000017237 LOC112919078 LOC112919078 INTS13 INTS13 WDR62 WDR62 SPRY1 SPRY1 KHDC3L KHDC3L CEP192 CEP192 SPRY2 SPRY2 RAB11A RAB11A KIF23 KIF23 TACC3 TACC3 ABRAXAS1 ABRAXAS1 CENPA CENPA ZW10 ZW10 SBDS SBDS PAX6 PAX6 LSM14A LSM14A SPC25 SPC25 AURKA AURKA DCTN2 DCTN2 UBXN2B UBXN2B ENSVVUP00000024659 ENSVVUP00000024659 PIBF1 PIBF1 ENSVVUP00000026085 ENSVVUP00000026085 MYBL2 MYBL2 NDE1 NDE1 DCTN6 DCTN6 TACC1 TACC1 ZNF207 ZNF207 TASOR TASOR KIF11 KIF11 PAFAH1B1 PAFAH1B1 SPICE1 SPICE1 CLASP2 CLASP2 RACGAP1 RACGAP1 TUBG1 TUBG1 TUBG1-2 TUBG1-2 INSC INSC HTT HTT MAP9 MAP9 ENSVVUP00000034938 ENSVVUP00000034938 RAB11B RAB11B FGF10 FGF10 KIFC1 KIFC1 NUMA1 NUMA1 ENSVVUP00000035680 ENSVVUP00000035680 CHEK2 CHEK2 ENSVVUP00000035979 ENSVVUP00000035979 FAM193B FAM193B ZCWPW2 ZCWPW2 NUSAP1 NUSAP1 VCP VCP CKAP5 CKAP5 KAT5 KAT5 WRAP73 WRAP73 CLASP1 CLASP1 GPSM1 GPSM1 PTPA PTPA AAAS AAAS AURKB AURKB NDEL1 NDEL1 EML1 EML1 ENSVVUP00000040212 ENSVVUP00000040212 STAG2 STAG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKHD1Fibrocystin. (4066 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10 isoform X3. (1330 aa)
FLNAfilamin-A isoform X1. (2646 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (507 aa)
DLGAP5Disks large-associated protein 5. (845 aa)
KHDC3L-2KHDC3-like protein. (162 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
EFHC1EF-hand domain-containing protein 1. (688 aa)
TOGARAM1TOG array regulator of axonemal microtubules protein 1 isoform X2. (1826 aa)
GPSM2G-protein-signaling modulator 2 isoform X1. (693 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
RMDN1Regulator of microtubule dynamics protein 1 isoform X1. (317 aa)
SAPCD2Suppressor APC domain-containing protein 2. (341 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X2. (593 aa)
CCDC61Coiled-coil domain-containing protein 61 isoform X5. (557 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (621 aa)
TOGARAM2TOG array regulator of axonemal microtubules protein 2 isoform X1. (991 aa)
KPNB1Importin subunit beta-1. (876 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2543 aa)
ENSVVUP00000004945annotation not available (98 aa)
DCTN1Dynactin subunit 1 isoform X6. (1285 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (729 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
LOC112911081Mitotic spindle assembly checkpoint protein MAD2A. (190 aa)
MAPRE1-2Microtubule-associated protein RP/EB family member 1. (126 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (772 aa)
BCCIPBRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (314 aa)
PLK1Serine/threonine-protein kinase PLK. (607 aa)
ABRAXAS2BRISC complex subunit Abraxas 2. (440 aa)
MZT1Mitotic-spindle organizing protein 1. (97 aa)
PRC1Protein regulator of cytokinesis 1 isoform X1. (567 aa)
STILSCL-interrupting locus protein. (1276 aa)
CENPHCentromere protein H. (301 aa)
ENSVVUP00000009373annotation not available (154 aa)
KIF4AChromosome-associated kinesin KIF4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
NDC80Kinetochore protein NDC80 homolog. (642 aa)
MAP10Microtubule-associated protein 10. (863 aa)
SMC3Structural maintenance of chromosomes protein. (1217 aa)
KIF27Kinesin-like protein KIF27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1398 aa)
NSFL1CNSFL1 cofactor p47. (348 aa)
TPX2Targeting protein for Xklp2. (740 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (540 aa)
TBCETubulin-specific chaperone E. (530 aa)
CENPECentromere-associated protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2396 aa)
NEK2Serine/threonine-protein kinase Nek2. (444 aa)
NUF2Kinetochore protein Nuf2. (464 aa)
MAP1SMicrotubule-associated protein 1S isoform X1. (1035 aa)
CEP126Centrosomal protein of 126 kDa isoform X1. (1119 aa)
ENSVVUP00000015176annotation not available (206 aa)
MAPRE1Microtubule-associated protein RP/EB family member 1. (195 aa)
TACC2Transforming acidic coiled-coil-containing protein 2 isoform X4. (2828 aa)
ANKFN1Ankyrin repeat and fibronectin type-III domain-containing protein 1. (416 aa)
CDK5RAP2CDK5 regulatory subunit-associated protein 2. (1889 aa)
EFHC2EF-hand domain-containing family member C2. (748 aa)
ENSVVUP00000016274annotation not available (188 aa)
NUDCNuclear migration protein nudC. (398 aa)
RCC1Regulator of chromosome condensation isoform X1. (492 aa)
ENSVVUP00000017237annotation not available (320 aa)
LOC112919078Nucleolar and spindle-associated protein 1-like isoform X1. (414 aa)
INTS13Integrator complex subunit 13 isoform X1. (706 aa)
WDR62LOW QUALITY PROTEIN: WD repeat-containing protein 62. (1558 aa)
SPRY1Protein sprouty homolog 1 isoform X1. (342 aa)
KHDC3LKHDC3-like protein. (214 aa)
CEP192Centrosomal protein of 192 kDa isoform X2. (2517 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
RAB11ARas-related protein Rab-11A. (216 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (953 aa)
TACC3LOW QUALITY PROTEIN: transforming acidic coiled-coil-containing protein 3. (843 aa)
ABRAXAS1BRCA1-A complex subunit Abraxas 1 isoform X1. (409 aa)
CENPAHistone H3-like centromeric protein A. (123 aa)
ZW10Centromere/kinetochore protein zw10 homolog isoform X1. (779 aa)
SBDSRibosome maturation protein SBDS. (250 aa)
PAX6Paired box protein Pax-6 isoform X2. (422 aa)
LSM14AProtein LSM14 homolog A isoform X3. (463 aa)
SPC25Kinetochore protein Spc25. (226 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (386 aa)
DCTN2Dynactin subunit 2 isoform X2. (397 aa)
UBXN2BUBX domain-containing protein 2B. (330 aa)
ENSVVUP00000024659annotation not available (103 aa)
PIBF1Progesterone-induced-blocking factor 1 isoform X1. (1111 aa)
ENSVVUP00000026085annotation not available (190 aa)
MYBL2Myb-related protein B. (685 aa)
NDE1Nuclear distribution protein nudE homolog 1. (346 aa)
DCTN6Dynactin subunit 6. (200 aa)
TACC1Transforming acidic coiled-coil-containing protein 1 isoform X1. (790 aa)
ZNF207BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform X1. (495 aa)
TASORProtein TASOR isoform X1. (1674 aa)
KIF11Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1099 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
SPICE1Spindle and centriole-associated protein 1 isoform X4. (859 aa)
CLASP2CLIP-associating protein 2 isoform X11. (1508 aa)
RACGAP1Rac GTPase-activating protein 1 isoform X2. (632 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (491 aa)
TUBG1-2Tubulin gamma-1 chain. (251 aa)
INSCProtein inscuteable homolog. (578 aa)
HTTHuntingtin. (3108 aa)
MAP9Microtubule-associated protein 9. (1085 aa)
ENSVVUP00000034938annotation not available (125 aa)
RAB11BRas-related protein Rab-11B. (218 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (693 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2153 aa)
ENSVVUP00000035680annotation not available (126 aa)
CHEK2Serine/threonine-protein kinase Chk2 isoform X1. (544 aa)
ENSVVUP00000035979annotation not available (362 aa)
FAM193BProtein FAM193B isoform X1. (929 aa)
ZCWPW2Zinc finger CW-type PWWP domain protein 2. (348 aa)
NUSAP1Nucleolar and spindle-associated protein 1 isoform X3. (421 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (839 aa)
CKAP5Cytoskeleton-associated protein 5 isoform X1. (2033 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa)
WRAP73WD repeat-containing protein WRAP73. (491 aa)
CLASP1CLIP-associating protein 1 isoform X4. (1551 aa)
GPSM1G-protein-signaling modulator 1 isoform X4. (649 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (323 aa)
AAASAladin isoform X1. (546 aa)
AURKBAurora kinase B isoform X3; Belongs to the protein kinase superfamily. (501 aa)
NDEL1Nuclear distribution protein nudE-like 1 isoform X1. (345 aa)
EML1Echinoderm microtubule-associated protein-like 1. (866 aa)
ENSVVUP00000040212annotation not available (169 aa)
STAG2Cohesin subunit SA-2 isoform X1. (1299 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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