(9 nodes) Positive regulation of xenophagy network (Vulpes vulpes)

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Your Input:
	ENSVVUP00000017517	annotation not available (118 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
	LRSAM1	E3 ubiquitin-protein ligase LRSAM1 isoform X1. (728 aa)
	TBK1	Serine/threonine-protein kinase TBK1 isoform X1. (820 aa)
	ENSVVUP00000024290	annotation not available (257 aa)
	NOD2	Nucleotide-binding oligomerization domain-containing protein 2. (1043 aa)
	NOD1	Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (375 aa)
	RNF31	E3 ubiquitin-protein ligase RNF31 isoform X3. (1076 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NOD1	NOD2	ENSVVUP00000028666	ENSVVUP00000026370	Nucleotide-binding oligomerization domain-containing protein 1.	Nucleotide-binding oligomerization domain-containing protein 2.	0.835
NOD1	RIPK2	ENSVVUP00000028666	ENSVVUP00000002520	Nucleotide-binding oligomerization domain-containing protein 1.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.994
NOD1	TBK1	ENSVVUP00000028666	ENSVVUP00000020356	Nucleotide-binding oligomerization domain-containing protein 1.	Serine/threonine-protein kinase TBK1 isoform X1.	0.422
NOD2	NOD1	ENSVVUP00000026370	ENSVVUP00000028666	Nucleotide-binding oligomerization domain-containing protein 2.	Nucleotide-binding oligomerization domain-containing protein 1.	0.835
NOD2	RIPK2	ENSVVUP00000026370	ENSVVUP00000002520	Nucleotide-binding oligomerization domain-containing protein 2.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.997
NOD2	RNF31	ENSVVUP00000026370	ENSVVUP00000040941	Nucleotide-binding oligomerization domain-containing protein 2.	E3 ubiquitin-protein ligase RNF31 isoform X3.	0.555
NOD2	TBK1	ENSVVUP00000026370	ENSVVUP00000020356	Nucleotide-binding oligomerization domain-containing protein 2.	Serine/threonine-protein kinase TBK1 isoform X1.	0.569
RIPK2	NOD1	ENSVVUP00000002520	ENSVVUP00000028666	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	Nucleotide-binding oligomerization domain-containing protein 1.	0.994
RIPK2	NOD2	ENSVVUP00000002520	ENSVVUP00000026370	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	Nucleotide-binding oligomerization domain-containing protein 2.	0.997
RIPK2	RNF31	ENSVVUP00000002520	ENSVVUP00000040941	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	E3 ubiquitin-protein ligase RNF31 isoform X3.	0.931
RIPK2	TBK1	ENSVVUP00000002520	ENSVVUP00000020356	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	Serine/threonine-protein kinase TBK1 isoform X1.	0.426
RNF31	NOD2	ENSVVUP00000040941	ENSVVUP00000026370	E3 ubiquitin-protein ligase RNF31 isoform X3.	Nucleotide-binding oligomerization domain-containing protein 2.	0.555
RNF31	RIPK2	ENSVVUP00000040941	ENSVVUP00000002520	E3 ubiquitin-protein ligase RNF31 isoform X3.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.931
RNF31	TBK1	ENSVVUP00000040941	ENSVVUP00000020356	E3 ubiquitin-protein ligase RNF31 isoform X3.	Serine/threonine-protein kinase TBK1 isoform X1.	0.965
TBK1	NOD1	ENSVVUP00000020356	ENSVVUP00000028666	Serine/threonine-protein kinase TBK1 isoform X1.	Nucleotide-binding oligomerization domain-containing protein 1.	0.422
TBK1	NOD2	ENSVVUP00000020356	ENSVVUP00000026370	Serine/threonine-protein kinase TBK1 isoform X1.	Nucleotide-binding oligomerization domain-containing protein 2.	0.569
TBK1	RIPK2	ENSVVUP00000020356	ENSVVUP00000002520	Serine/threonine-protein kinase TBK1 isoform X1.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.426
TBK1	RNF31	ENSVVUP00000020356	ENSVVUP00000040941	Serine/threonine-protein kinase TBK1 isoform X1.	E3 ubiquitin-protein ligase RNF31 isoform X3.	0.965