71 items (Vulpes vulpes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FAM83D	Protein FAM83D. (420 aa)
	SGO1	Shugoshin 1. (524 aa)
	CDC6	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (516 aa)
	RMDN1	Regulator of microtubule dynamics protein 1 isoform X1. (317 aa)
	AURKC	Aurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
	CALM3	Calmodulin-1; Belongs to the calmodulin family. (149 aa)
	SPDL1	Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (621 aa)
	ASPM	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein. (3515 aa)
	ENSVVUP00000005911	annotation not available (91 aa)
	MAPRE1-2	Microtubule-associated protein RP/EB family member 1. (126 aa)
	BCCIP	BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (314 aa)
	CEP95	Centrosomal protein of 95 kDa. (816 aa)
	ENSVVUP00000009373	annotation not available (154 aa)
	MAP10	Microtubule-associated protein 10. (863 aa)
	YPEL5	Protein yippee-like; Belongs to the yippee family. (121 aa)
	HSF1	Heat shock factor protein 1 isoform X2. (554 aa)
	FAM110A	Protein FAM110A. (422 aa)
	CENPF	Centromere protein F. (3062 aa)
	TPX2	Targeting protein for Xklp2. (740 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (540 aa)
	CEP19	Centrosomal protein of 19 kDa. (163 aa)
	ENSVVUP00000011611	annotation not available (205 aa)
	UBL3	Ubiquitin-like protein. (121 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (532 aa)
	LOC112908355	LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like. (270 aa)
	MAPRE1	Microtubule-associated protein RP/EB family member 1. (195 aa)
	AUNIP	Aurora kinase A and ninein-interacting protein. (416 aa)
	CEP85	Centrosomal protein of 85 kDa. (767 aa)
	MTCL1	Microtubule cross-linking factor 1 isoform X1. (1688 aa)
	CDK5RAP2	CDK5 regulatory subunit-associated protein 2. (1889 aa)
	CNTRL	Centriolin. (2378 aa)
	LOC112915139	Protein yippee-like 5. (121 aa)
	TBCCD1	TBCC domain-containing protein 1. (557 aa)
	WDR62	LOW QUALITY PROTEIN: WD repeat-containing protein 62. (1558 aa)
	SBDS	Ribosome maturation protein SBDS. (250 aa)
	UNC119	Protein unc-119 homolog A. (242 aa)
	CEP44	Centrosomal protein of 44 kDa isoform X1. (386 aa)
	SPAG5	Sperm-associated antigen 5 isoform X3. (1088 aa)
	RSKR	Uncharacterized serine/threonine-protein kinase SgK494 isoform X2. (393 aa)
	RAE1	mRNA export factor. (371 aa)
	CTNND2	Catenin delta-2. (754 aa)
	UBXN2B	UBX domain-containing protein 2B. (330 aa)
	LOC112934252	Catenin delta-2-like isoform X1. (227 aa)
	CALM1	Calmodulin 1. (149 aa)
	DDX11	ATP-dependent DNA helicase DDX11. (961 aa)
	CSPP1	Centrosome and spindle pole-associated protein 1 isoform X1. (1144 aa)
	RMDN2	Regulator of microtubule dynamics protein 2. (504 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1327 aa)
	PKP4	Plakophilin-4 isoform X1. (1208 aa)
	BRCC3	Lys-63-specific deubiquitinase BRCC36. (263 aa)
	CCDC155	Protein KASH5. (616 aa)
	KLHL22	Kelch-like protein 22. (634 aa)
	TUBG1	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (491 aa)
	TUBG1-2	Tubulin gamma-1 chain. (251 aa)
	CDC25B	M-phase inducer phosphatase 2 isoform X2. (533 aa)
	ENSVVUP00000034938	annotation not available (125 aa)
	ENSVVUP00000035680	annotation not available (126 aa)
	SPOUT1	Putative methyltransferase C9orf114 homolog isoform X1. (358 aa)
	NOL9	Polynucleotide 5'-hydroxyl-kinase NOL9. (1070 aa)
	RMDN3	Regulator of microtubule dynamics protein 3. (503 aa)
	MAPKBP1	Mitogen-activated protein kinase-binding protein 1 isoform X1. (1503 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (555 aa)
	ANKRD53	Ankyrin repeat domain-containing protein 53. (489 aa)
	AAAS	Aladin isoform X1. (546 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (588 aa)
	CDADC1	Cytidine and dCMP deaminase domain-containing protein 1. (490 aa)
	TPT1	Translationally-controlled tumor protein; Belongs to the TCTP family. (195 aa)
	ENSVVUP00000040212	annotation not available (169 aa)
	DHX35	Probable ATP-dependent RNA helicase DHX35. (771 aa)
	DLGAP5	Disks large-associated protein 5. (845 aa)
	NIN	Ninein isoform X2. (2134 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAAS	RAE1	ENSVVUP00000039465	ENSVVUP00000023560	Aladin isoform X1.	mRNA export factor.	0.873
ASPM	AURKC	ENSVVUP00000004319	ENSVVUP00000003170	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Aurora kinase C; Belongs to the protein kinase superfamily.	0.610
ASPM	CALM1	ENSVVUP00000004319	ENSVVUP00000024824	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Calmodulin 1.	0.626
ASPM	CALM3	ENSVVUP00000004319	ENSVVUP00000003523	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Calmodulin-1; Belongs to the calmodulin family.	0.626
ASPM	CDC6	ENSVVUP00000004319	ENSVVUP00000001070	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.446
ASPM	CENPF	ENSVVUP00000004319	ENSVVUP00000011370	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Centromere protein F.	0.967
ASPM	DLGAP5	ENSVVUP00000004319	ENSVVUP00000041600	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Disks large-associated protein 5.	0.966
ASPM	ENSVVUP00000005911	ENSVVUP00000004319	ENSVVUP00000005911	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	annotation not available	0.626
ASPM	KATNAL2	ENSVVUP00000004319	ENSVVUP00000039569	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.412
ASPM	NIN	ENSVVUP00000004319	ENSVVUP00000041859	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Ninein isoform X2.	0.514
ASPM	SGO1	ENSVVUP00000004319	ENSVVUP00000000467	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Shugoshin 1.	0.675
ASPM	SPAG5	ENSVVUP00000004319	ENSVVUP00000023161	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Sperm-associated antigen 5 isoform X3.	0.957
ASPM	TPX2	ENSVVUP00000004319	ENSVVUP00000011443	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	Targeting protein for Xklp2.	0.450
ASPM	WDR62	ENSVVUP00000004319	ENSVVUP00000018501	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	LOW QUALITY PROTEIN: WD repeat-containing protein 62.	0.787
AURKC	ASPM	ENSVVUP00000003170	ENSVVUP00000004319	Aurora kinase C; Belongs to the protein kinase superfamily.	LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein.	0.610
AURKC	CDC6	ENSVVUP00000003170	ENSVVUP00000001070	Aurora kinase C; Belongs to the protein kinase superfamily.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.501
AURKC	CENPF	ENSVVUP00000003170	ENSVVUP00000011370	Aurora kinase C; Belongs to the protein kinase superfamily.	Centromere protein F.	0.548
AURKC	DLGAP5	ENSVVUP00000003170	ENSVVUP00000041600	Aurora kinase C; Belongs to the protein kinase superfamily.	Disks large-associated protein 5.	0.663
AURKC	ENSVVUP00000009373	ENSVVUP00000003170	ENSVVUP00000009373	Aurora kinase C; Belongs to the protein kinase superfamily.	annotation not available	0.466
AURKC	ENSVVUP00000034938	ENSVVUP00000003170	ENSVVUP00000034938	Aurora kinase C; Belongs to the protein kinase superfamily.	annotation not available	0.466