(36 nodes) SCF ubiquitin ligase complex network (Vulpes vulpes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCNF	cyclin-F; Belongs to the cyclin family. (758 aa)
	BTRC	F-box/WD repeat-containing protein 1A isoform X1. (605 aa)
	FBXO31	F-box only protein 31 isoform X2. (476 aa)
	FBXO9	F-box only protein 9 isoform X1. (435 aa)
	FBXO4	F-box only protein 4. (265 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	ENSVVUP00000002230	annotation not available (93 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXW11	F-box/WD repeat-containing protein 11 isoform X2. (593 aa)
	FBXL15	F-box and leucine rich repeat protein 15. (403 aa)
	FBXO41	F-box only protein 41. (578 aa)
	FBXL6	F-box/LRR-repeat protein 6. (840 aa)
	FBXO27	F-box only protein 27. (156 aa)
	FBXO17	F-box only protein 17. (267 aa)
	TMEM183A	Transmembrane protein 183A isoform X1. (371 aa)
	FBH1	F-box DNA helicase 1. (1163 aa)
	FBXO42	F-box only protein 42 isoform X1. (717 aa)
	FBXO2	F-box only protein 2. (387 aa)
	FBXL19	F-box/LRR-repeat protein 19 isoform X2. (696 aa)
	FBXO25	F-box only protein 25 isoform X1. (420 aa)
	FBXW5	F-box/WD repeat-containing protein 5 isoform X1. (620 aa)
	USP47	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1349 aa)
	FBXL2	F-box/LRR-repeat protein 2 isoform X1. (436 aa)
	FBXO33	LOW QUALITY PROTEIN: F-box only protein 33. (530 aa)
	FBXL14	F-box/LRR-repeat protein 14. (406 aa)
	FBXL3	F-box/LRR-repeat protein 3. (438 aa)
	LOC112917031	LOW QUALITY PROTEIN: F-box/LRR-repeat protein 21-like. (423 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (776 aa)
	FBXL5	F-box/LRR-repeat protein 5. (856 aa)
	FBXL17	F-box/LRR-repeat protein 17. (220 aa)
	ZC3HC1	Nuclear-interacting partner of ALK. (482 aa)
	FBXL22	F-box and leucine-rich protein 22. (215 aa)
	ENSVVUP00000015812	annotation not available (353 aa)
	SKP2	S-phase kinase-associated protein 2. (436 aa)
	ENSVVUP00000013849	annotation not available (54 aa)
	RBX1	E3 ubiquitin-protein ligase RBX1 isoform X2. (108 aa)

Your Current Organism:

Vulpes vulpes

NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTRC	CCNF	ENSVVUP00000000785	ENSVVUP00000012489	F-box/WD repeat-containing protein 1A isoform X1.	cyclin-F; Belongs to the cyclin family.	0.408
BTRC	CUL1	ENSVVUP00000000785	ENSVVUP00000022561	F-box/WD repeat-containing protein 1A isoform X1.	Cullin-1; Belongs to the cullin family.	0.998
BTRC	FBXO2	ENSVVUP00000000785	ENSVVUP00000039937	F-box/WD repeat-containing protein 1A isoform X1.	F-box only protein 2.	0.929
BTRC	FBXO4	ENSVVUP00000000785	ENSVVUP00000002192	F-box/WD repeat-containing protein 1A isoform X1.	F-box only protein 4.	0.909
BTRC	FBXW11	ENSVVUP00000000785	ENSVVUP00000003303	F-box/WD repeat-containing protein 1A isoform X1.	F-box/WD repeat-containing protein 11 isoform X2.	0.971
BTRC	RBX1	ENSVVUP00000000785	ENSVVUP00000009233	F-box/WD repeat-containing protein 1A isoform X1.	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.995
BTRC	SKP2	ENSVVUP00000000785	ENSVVUP00000014689	F-box/WD repeat-containing protein 1A isoform X1.	S-phase kinase-associated protein 2.	0.944
BTRC	USP47	ENSVVUP00000000785	ENSVVUP00000035136	F-box/WD repeat-containing protein 1A isoform X1.	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family.	0.579
CCNF	BTRC	ENSVVUP00000012489	ENSVVUP00000000785	cyclin-F; Belongs to the cyclin family.	F-box/WD repeat-containing protein 1A isoform X1.	0.408
CCNF	CKS1B	ENSVVUP00000012489	ENSVVUP00000002533	cyclin-F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.661
CCNF	CKS2	ENSVVUP00000012489	ENSVVUP00000002195	cyclin-F; Belongs to the cyclin family.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.661
CCNF	CUL1	ENSVVUP00000012489	ENSVVUP00000022561	cyclin-F; Belongs to the cyclin family.	Cullin-1; Belongs to the cullin family.	0.887
CCNF	ENSVVUP00000013849	ENSVVUP00000012489	ENSVVUP00000013849	cyclin-F; Belongs to the cyclin family.	annotation not available	0.661
CCNF	RBX1	ENSVVUP00000012489	ENSVVUP00000009233	cyclin-F; Belongs to the cyclin family.	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.672
CCNF	SKP2	ENSVVUP00000012489	ENSVVUP00000014689	cyclin-F; Belongs to the cyclin family.	S-phase kinase-associated protein 2.	0.824
CKS1B	CCNF	ENSVVUP00000002533	ENSVVUP00000012489	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	cyclin-F; Belongs to the cyclin family.	0.661
CKS1B	CKS2	ENSVVUP00000002533	ENSVVUP00000002195	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.901
CKS1B	CUL1	ENSVVUP00000002533	ENSVVUP00000022561	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Cullin-1; Belongs to the cullin family.	0.973
CKS1B	RBX1	ENSVVUP00000002533	ENSVVUP00000009233	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	E3 ubiquitin-protein ligase RBX1 isoform X2.	0.940
CKS1B	SKP2	ENSVVUP00000002533	ENSVVUP00000014689	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	S-phase kinase-associated protein 2.	0.987