STRINGSTRING
ABCC11 ABCC11 MCM3 MCM3 ABCC9 ABCC9 CDC6 CDC6 ABCB1 ABCB1 ABCG5 ABCG5 ATAD1 ATAD1 ABCG8 ABCG8 DNAH6 DNAH6 BCS1L BCS1L RAD51B RAD51B NVL NVL SPG7 SPG7 DNAH5 DNAH5 ATAD3A ATAD3A ORC1 ORC1 IGHMBP2 IGHMBP2 ABCD4 ABCD4 KATNA1 KATNA1 NSF NSF PSMC4 PSMC4 PSMC5 PSMC5 NAV1 NAV1 AK9 AK9 ABCC4 ABCC4 LOC112926201 LOC112926201 ABCB10 ABCB10 LOC112908324 LOC112908324 ABCC5 ABCC5 ABCF3 ABCF3 DNAH11 DNAH11 NLRP2 NLRP2 ABCA8 ABCA8 ABCF2 ABCF2 ABCA9 ABCA9 ABCA6 ABCA6 ABCB5 ABCB5 ABCG2 ABCG2 ABCB8 ABCB8 SPAST SPAST LOC112908325 LOC112908325 YME1L1 YME1L1 LOC112908326 LOC112908326 ABCA12 ABCA12 ABCA5 ABCA5 ABCE1 ABCE1 LOC112909126 LOC112909126 ABCA3 ABCA3 KATNAL1 KATNAL1 ABCF1 ABCF1 NAV3 NAV3 FIGNL1 FIGNL1 CFTR CFTR MDN1 MDN1 ORC4 ORC4 ABCC3 ABCC3 NAV2 NAV2 ATAD5 ATAD5 CHTF18 CHTF18 RFC4 RFC4 AFG3L2 AFG3L2 SPATA5 SPATA5 LONP1 LONP1 DYNC2H1 DYNC2H1 CLPX CLPX SPATA5L1 SPATA5L1 RFC1 RFC1 PSMC2 PSMC2 ATAD2B ATAD2B HELZ2 HELZ2 PEX1 PEX1 ASCC3 ASCC3 MCM9 MCM9 ABCC12 ABCC12 LONP2 LONP2 ATAD2 ATAD2 ABCD2 ABCD2 ABCG1 ABCG1 ABCB11 ABCB11 VPS4A VPS4A VPS4B VPS4B PSMC1 PSMC1 RUVBL1 RUVBL1 FIGN FIGN WRNIP1 WRNIP1 ABCC1 ABCC1 ABCC6 ABCC6 SRP54 SRP54 SRPRA SRPRA DNAH12 DNAH12 RAD51D RAD51D ATP5F1B ATP5F1B ABCA4 ABCA4 ABCD3 ABCD3 TRIP13 TRIP13 DMC1 DMC1 ABCA7 ABCA7 RUVBL2 RUVBL2 ABCG4 ABCG4 DNAH3 DNAH3 MCM7 MCM7 MCM8 MCM8 PSMC3 PSMC3 LOC112917709 LOC112917709 ABCC8 ABCC8 ABCC2 ABCC2 ABCB7 ABCB7 RFC2 RFC2 CLPB CLPB TAP2 TAP2 TAP1 TAP1 ABCB6 ABCB6 DNAH7 DNAH7 DNAH8 DNAH8 RFC3 RFC3 RAD51 RAD51 VCP VCP ABCA1 ABCA1 DNAH10 DNAH10 PEX6 PEX6 DNAH2 DNAH2 ABCB9 ABCB9 KATNAL2 KATNAL2 DYNC1H1 DYNC1H1 VWA8 VWA8 ABCC10 ABCC10 TOR4A TOR4A ABCD1 ABCD1 PSMC6 PSMC6 DNAH9 DNAH9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCC11ATP-binding cassette sub-family C member 11 isoform X1. (1383 aa)
MCM3DNA helicase; Belongs to the MCM family. (825 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (516 aa)
ABCB1Multidrug resistance protein 1. (2440 aa)
ABCG5ATP-binding cassette sub-family G member 5. (652 aa)
ATAD1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (377 aa)
ABCG8ATP-binding cassette sub-family G member 8. (690 aa)
DNAH6Dynein heavy chain 6, axonemal. (4153 aa)
BCS1LMitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (405 aa)
RAD51BDNA repair protein RAD51 homolog 2 isoform X3. (271 aa)
NVLNuclear valosin-containing protein-like isoform X1. (854 aa)
SPG7Paraplegin isoform X1. (793 aa)
DNAH5Dynein heavy chain 5, axonemal. (4584 aa)
ATAD3AATPase family AAA domain-containing protein 3A. (591 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa)
IGHMBP2DNA-binding protein SMUBP-2 isoform X2. (1005 aa)
ABCD4ATP-binding cassette sub-family D member 4 isoform X1. (606 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (628 aa)
NSFVesicle-fusing ATPase isoform X1. (747 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMC526S proteasome regulatory subunit 8 isoform X1; Belongs to the AAA ATPase family. (406 aa)
NAV1Neuron navigator 1. (2141 aa)
AK9Adenylate kinase 9 isoform X2. (1989 aa)
ABCC4Multidrug resistance-associated protein 4. (1318 aa)
LOC112926201LOW QUALITY PROTEIN: replication factor C subunit 5-like. (304 aa)
ABCB10ATP-binding cassette sub-family B member 10, mitochondrial. (690 aa)
LOC112908324ATP-binding cassette sub-family A member 3-like. (1635 aa)
ABCC5Multidrug resistance-associated protein 5 isoform X1. (1485 aa)
ABCF3ATP-binding cassette sub-family F member 3 isoform X1. (741 aa)
DNAH11LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal. (4441 aa)
NLRP2NACHT, LRR and PYD domains-containing protein 2. (191 aa)
ABCA8ATP-binding cassette sub-family A member 8-like isoform X1. (1622 aa)
ABCF2ATP-binding cassette sub-family F member 2. (714 aa)
ABCA9ATP-binding cassette sub-family A member 9. (360 aa)
ABCA6ATP-binding cassette sub-family A member 6. (399 aa)
ABCB5ATP-binding cassette sub-family B member 5. (1257 aa)
ABCG2ATP-binding cassette sub-family G member 2. (650 aa)
ABCB8ATP-binding cassette sub-family B member 8, mitochondrial isoform X1. (713 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (540 aa)
LOC112908325ATP-binding cassette sub-family A member 3-like. (1679 aa)
YME1L1ATP-dependent zinc metalloprotease YME1L1 isoform X1. (729 aa)
LOC112908326ATP-binding cassette sub-family A member 3-like. (597 aa)
ABCA12ATP-binding cassette sub-family A member 12. (2609 aa)
ABCA5ATP-binding cassette sub-family A member 5. (1642 aa)
ABCE1ATP-binding cassette sub-family E member 1. (599 aa)
LOC112909126ATP-binding cassette sub-family A member 17-like. (1786 aa)
ABCA3ATP-binding cassette sub-family A member 3. (1771 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (532 aa)
ABCF1ATP-binding cassette sub-family F member 1 isoform X1. (839 aa)
NAV3Neuron navigator 3 isoform X1. (2355 aa)
FIGNL1Fidgetin-like protein 1; Belongs to the AAA ATPase family. (676 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1493 aa)
MDN1LOW QUALITY PROTEIN: midasin. (3132 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
ABCC3Canalicular multispecific organic anion transporter 2. (1326 aa)
NAV2LOW QUALITY PROTEIN: neuron navigator 2. (2288 aa)
ATAD5ATPase family AAA domain-containing protein 5. (1882 aa)
CHTF18Chromosome transmission fidelity protein 18 homolog. (1099 aa)
RFC4Replication factor C subunit 4. (424 aa)
AFG3L2AFG3-like protein 2 isoform X1. (806 aa)
SPATA5Spermatogenesis-associated protein 5 isoform X1. (893 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (960 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1. (4272 aa)
CLPXATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. (621 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1 isoform X1. (755 aa)
RFC1Replication factor C subunit 1. (1166 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ATAD2BATPase family AAA domain-containing protein 2B. (1397 aa)
HELZ2Helicase with zinc finger domain 2. (2993 aa)
PEX1Peroxisome biogenesis factor 1. (1364 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3 isoform X1. (2202 aa)
MCM9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1141 aa)
ABCC12Multidrug resistance-associated protein 9. (1367 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
ATAD2ATPase family AAA domain-containing protein 2. (1373 aa)
ABCD2ATP-binding cassette sub-family D member 2. (742 aa)
ABCG1ATP-binding cassette sub-family G member 1 isoform X1. (656 aa)
ABCB11Bile salt export pump. (1267 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (518 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (461 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (453 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
FIGNFidgetin; Belongs to the AAA ATPase family. (385 aa)
WRNIP1ATPase WRNIP1. (445 aa)
ABCC1Multidrug resistance-associated protein 1. (1465 aa)
ABCC6Multidrug resistance-associated protein 6 isoform X1. (1504 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (530 aa)
SRPRASignal recognition particle receptor subunit alpha. (638 aa)
DNAH12Dynein heavy chain 12, axonemal. (3297 aa)
RAD51DDNA repair protein RAD51 homolog 4 isoform X1. (328 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
ABCA4Retinal-specific ATP-binding cassette transporter. (2372 aa)
ABCD3ATP-binding cassette sub-family D member 3. (668 aa)
TRIP13Pachytene checkpoint protein 2 homolog; Belongs to the AAA ATPase family. (442 aa)
DMC1Meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family. (333 aa)
ABCA7ATP-binding cassette sub-family A member 7. (2042 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (512 aa)
ABCG4ATP-binding cassette sub-family G member 4. (646 aa)
DNAH3Dynein heavy chain 3, axonemal. (946 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (653 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (868 aa)
PSMC326S proteasome regulatory subunit 6A isoform X2; Belongs to the AAA ATPase family. (581 aa)
LOC112917709Multidrug resistance-associated protein 1-like. (1257 aa)
ABCC8ATP-binding cassette sub-family C member 8 isoform X4. (1627 aa)
ABCC2Canalicular multispecific organic anion transporter 1. (1544 aa)
ABCB7ATP-binding cassette sub-family B member 7, mitochondrial isoform X1. (752 aa)
RFC2Replication factor C subunit 2 isoform X1. (496 aa)
CLPBCaseinolytic peptidase B protein homolog isoform X1. (713 aa)
TAP2Antigen peptide transporter 2 isoform X1. (733 aa)
TAP1Antigen peptide transporter 1. (750 aa)
ABCB6ATP-binding cassette sub-family B member 6, mitochondrial. (979 aa)
DNAH7Dynein heavy chain 7, axonemal. (4042 aa)
DNAH8Dynein heavy chain 8, axonemal. (4725 aa)
RFC3Replication factor C subunit 3 isoform X1. (355 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (348 aa)
VCPTransitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (839 aa)
ABCA1ATP-binding cassette sub-family A member 1. (2230 aa)
DNAH10Dynein heavy chain 10, axonemal. (4540 aa)
PEX6Peroxisome biogenesis factor 6. (938 aa)
DNAH2Dynein heavy chain 2, axonemal isoform X1. (4444 aa)
ABCB9ATP-binding cassette sub-family B member 9 isoform X1. (723 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (588 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (697 aa)
VWA8Von Willebrand factor A domain-containing protein 8. (1836 aa)
ABCC10Multidrug resistance-associated protein 7 isoform X1. (1490 aa)
TOR4Atorsin-4A. (424 aa)
ABCD1ATP-binding cassette sub-family D member 1. (516 aa)
PSMC626S proteasome regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (403 aa)
DNAH9Dynein heavy chain 9, axonemal. (4396 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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