STRINGSTRING
PKP1 PKP1 CAPG CAPG SATB1 SATB1 CLSPN CLSPN ENSVVUP00000000565 ENSVVUP00000000565 ENSVVUP00000042744 ENSVVUP00000042744 SH3GLB1 SH3GLB1 LMNB1 LMNB1 BCAP31 BCAP31 ENSVVUP00000040954 ENSVVUP00000040954 ENSVVUP00000040953 ENSVVUP00000040953 ENSVVUP00000040952 ENSVVUP00000040952 DSG2 DSG2 DSG3 DSG3 DSG1 DSG1 SH3GLB2 SH3GLB2 TMEM198 TMEM198 SPTAN1 SPTAN1 ADD1 ADD1 PRKCD PRKCD APC2 APC2 STK25 STK25 LOC112922409 LOC112922409 EPPK1 EPPK1 SCIN SCIN PLEC PLEC BCAP29 BCAP29 ACIN1 ACIN1 TJP1 TJP1 CASP8 CASP8 PLA2G12A PLA2G12A PTK2 PTK2 GSN GSN STK26 STK26 CDH1 CDH1 CASP3 CASP3 APC APC ENSVVUP00000016799 ENSVVUP00000016799 ENSVVUP00000016202 ENSVVUP00000016202 ENSVVUP00000014940 ENSVVUP00000014940 BIRC2 BIRC2 MAP2 MAP2 GAS2 GAS2 CASP7 CASP7 BMX BMX DBNL DBNL ENSVVUP00000010095 ENSVVUP00000010095 STK24 STK24 OCLN OCLN PRKCQ PRKCQ LMNA LMNA CTNNB1 CTNNB1 MAPT MAPT DSP DSP LOC112924654 LOC112924654 TJP3 TJP3 ROCK1 ROCK1 VIM VIM TJP2 TJP2 LMNB2 LMNB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKP1Plakophilin-1. (727 aa)
CAPGMacrophage-capping protein. (429 aa)
SATB1DNA-binding protein SATB. (696 aa)
CLSPNClaspin isoform X2. (667 aa)
ENSVVUP00000000565annotation not available (253 aa)
ENSVVUP00000042744annotation not available (86 aa)
SH3GLB1endophilin-B1 isoform X1. (401 aa)
LMNB1lamin-B1 isoform X1; Belongs to the intermediate filament family. (586 aa)
BCAP31B-cell receptor-associated protein 31. (446 aa)
ENSVVUP00000040954annotation not available (105 aa)
ENSVVUP00000040953annotation not available (112 aa)
ENSVVUP00000040952annotation not available (101 aa)
DSG2Desmoglein-2. (1116 aa)
DSG3Desmoglein-3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (960 aa)
DSG1Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1020 aa)
SH3GLB2endophilin-B2 isoform X2. (430 aa)
TMEM198Transmembrane protein 198 isoform X2. (360 aa)
SPTAN1Spectrin alpha chain, non-erythrocytic 1 isoform X5. (2470 aa)
ADD1Alpha-adducin isoform X1. (783 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
APC2Adenomatous polyposis coli protein 2. (1719 aa)
STK25Serine/threonine-protein kinase 25. (467 aa)
LOC112922409Transmembrane protein 198-like isoform X2. (350 aa)
EPPK1Epiplakin. (3151 aa)
SCINAdseverin isoform X2. (761 aa)
PLECPlectin. (4948 aa)
BCAP29B-cell receptor-associated protein 29. (236 aa)
ACIN1Apoptotic chromatin condensation inducer in the nucleus isoform X1. (1338 aa)
TJP1Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1790 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (397 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (240 aa)
PTK2Focal adhesion kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1059 aa)
GSNGelsolin isoform X1. (1236 aa)
STK26Serine/threonine-protein kinase 26. (416 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (355 aa)
APCAdenomatous polyposis coli protein isoform X1. (2862 aa)
ENSVVUP00000016799annotation not available (89 aa)
ENSVVUP00000016202annotation not available (61 aa)
ENSVVUP00000014940annotation not available (115 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (459 aa)
MAP2Microtubule-associated protein. (1939 aa)
GAS2Growth arrest-specific protein 2. (313 aa)
CASP7Caspase-7 isoform X2; Belongs to the peptidase C14A family. (301 aa)
BMXTyrosine-protein kinase. (655 aa)
DBNLDrebrin-like protein isoform X3. (518 aa)
ENSVVUP00000010095annotation not available (130 aa)
STK24Serine/threonine-protein kinase 24 isoform X1. (456 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (560 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (463 aa)
LMNALamin; Belongs to the intermediate filament family. (685 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
MAPTMicrotubule-associated protein. (509 aa)
DSPDesmoplakin isoform X2. (2215 aa)
LOC112924654Cadherin-1-like. (676 aa)
TJP3LOW QUALITY PROTEIN: tight junction protein ZO-3; Belongs to the MAGUK family. (869 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1366 aa)
VIMVimentin; Belongs to the intermediate filament family. (463 aa)
TJP2Tight junction protein ZO-2 isoform X4; Belongs to the MAGUK family. (1195 aa)
LMNB2lamin-B2; Belongs to the intermediate filament family. (667 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.