STRINGSTRING
ENSVVUP00000005393 ENSVVUP00000005393 ENSVVUP00000005911 ENSVVUP00000005911 GNB1 GNB1 GNB4 GNB4 PRKCA PRKCA OPRM1 OPRM1 PRKAR1A PRKAR1A PRKX PRKX PDE4C PDE4C GNG12 GNG12 PRKCG PRKCG CDK5 CDK5 GNG4 GNG4 PPP1CA PPP1CA GRK2 GRK2 PPP2R1A PPP2R1A GNB3 GNB3 GNG13 GNG13 PLA2G4A PLA2G4A CAMK4 CAMK4 GNAL GNAL ADCY3 ADCY3 ENSVVUP00000020928 ENSVVUP00000020928 POMC POMC ENSVVUP00000020942 ENSVVUP00000020942 PDE4B PDE4B GNGT1 GNGT1 ENSVVUP00000021103 ENSVVUP00000021103 PPP2R1B PPP2R1B ADCY9 ADCY9 CAMKK2 CAMKK2 PDE1A PDE1A ADCY8 ADCY8 GNA14 GNA14 PDE4A PDE4A ADCY2 ADCY2 CALM1 CALM1 ADCY7 ADCY7 GNAI1 GNAI1 GNAT3 GNAT3 ADCY6 ADCY6 PPP2CB PPP2CB MAPK1 MAPK1 PDE1C PDE1C PPP2CA PPP2CA PDE4D PDE4D THAP7 THAP7 PRKAR2B PRKAR2B PLCB4 PLCB4 PLCB1 PLCB1 ENSVVUP00000032127 ENSVVUP00000032127 GNB2 GNB2 PDE1B PDE1B PRKCD PRKCD GNG14 GNG14 THAP6 THAP6 ENSVVUP00000034870 ENSVVUP00000034870 GNAI3 GNAI3 GNG8 GNG8 CALM3 CALM3 GNG7 GNG7 ENSVVUP00000005296 ENSVVUP00000005296 GNA11 GNA11 GNA15 GNA15 GNGT2 GNGT2 ADCY5 ADCY5 DCLK1-2 DCLK1-2 DCLK1 DCLK1 PRKACB PRKACB GNG3 GNG3 PLCB3 PLCB3 GNG2 GNG2 ADCY1 ADCY1 PRKAR2A PRKAR2A ADCY4 ADCY4 PRKAR1B PRKAR1B GNAI2 GNAI2 PPP2R5D PPP2R5D PRKACA PRKACA LRBA LRBA GNG5 GNG5 PDYN PDYN CAMKK1 CAMKK1 PLCB2 PLCB2 NBEA NBEA GNB5 GNB5 CNBD2 CNBD2 ENSVVUP00000001459 ENSVVUP00000001459 PPP1R1B PPP1R1B GNAQ GNAQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSVVUP00000005393annotation not available (155 aa)
ENSVVUP00000005911annotation not available (91 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)
OPRM1Mu-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (417 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (381 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (333 aa)
PDE4CPhosphodiesterase. (725 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
CDK5Cyclin-dependent-like kinase 5 isoform X3; Belongs to the protein kinase superfamily. (383 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (105 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (647 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (626 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (270 aa)
PLA2G4APhospholipase A2. (749 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV; Belongs to the protein kinase superfamily. (521 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha isoform X1. (380 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1314 aa)
ENSVVUP00000020928annotation not available (145 aa)
POMCLOW QUALITY PROTEIN: pro-opiomelanocortin. (231 aa)
ENSVVUP00000020942annotation not available (127 aa)
PDE4BPhosphodiesterase. (547 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSVVUP00000021103annotation not available (69 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2. (656 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1352 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (583 aa)
PDE1APhosphodiesterase. (533 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (365 aa)
PDE4APhosphodiesterase. (1017 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1051 aa)
CALM1Calmodulin 1. (149 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1076 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X2. (377 aa)
GNAT3Guanine nucleotide-binding protein G(T) subunit alpha-3. (354 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PPP2CBSerine/threonine-protein phosphatase. (279 aa)
MAPK1Mitogen-activated protein kinase. (392 aa)
PDE1CPhosphodiesterase. (709 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PDE4DPhosphodiesterase. (679 aa)
THAP7THAP domain-containing protein 7. (313 aa)
PRKAR2BcAMP-dependent protein kinase type II-beta regulatory subunit. (338 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
ENSVVUP00000032127annotation not available (112 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (372 aa)
PDE1BCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform X1; Belongs to the cyclic nucleotide phosphodiesterase family. (583 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (674 aa)
GNG14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
THAP6THAP domain-containing protein 6. (222 aa)
ENSVVUP00000034870annotation not available (88 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CALM3Calmodulin-1; Belongs to the calmodulin family. (149 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSVVUP00000005296annotation not available (88 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (361 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1200 aa)
DCLK1-2Serine/threonine-protein kinase DCLK1 isoform X7. (329 aa)
DCLK1Serine/threonine-protein kinase DCLK1 isoform X6; Belongs to the protein kinase superfamily. (423 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (103 aa)
ADCY1Adenylate cyclase type 1-like. (919 aa)
PRKAR2AcAMP-dependent protein kinase type II-alpha regulatory subunit. (401 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
PRKAR1BcAMP-dependent protein kinase type I-beta regulatory subunit. (389 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform X1. (355 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (604 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
LRBALipopolysaccharide-responsive and beige-like anchor protein isoform X2. (2773 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PDYNproenkephalin-B. (256 aa)
CAMKK1Calcium/calmodulin-dependent protein kinase kinase 1. (505 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1177 aa)
NBEANeurobeachin isoform X1. (3003 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (342 aa)
CNBD2Cyclic nucleotide-binding domain-containing protein 2. (695 aa)
ENSVVUP00000001459annotation not available (74 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (166 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
Your Current Organism:
Vulpes vulpes
NCBI taxonomy Id: 9627
Other names: Canis vulpes, V. vulpes, red fox, silver fox
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